| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-114 |
Sentence |
denotes |
A new epidermal growth factor-like domain in the human core protein for the large cartilage-specific proteoglycan. |
| T1 |
0-114 |
Sentence |
denotes |
A new epidermal growth factor-like domain in the human core protein for the large cartilage-specific proteoglycan. |
| T2 |
115-163 |
Sentence |
denotes |
Evidence for alternative splicing of the domain. |
| T2 |
115-163 |
Sentence |
denotes |
Evidence for alternative splicing of the domain. |
| T3 |
164-273 |
Sentence |
denotes |
A series of cDNA clones for the human core protein of the large cartilage-specific proteoglycan was isolated. |
| T3 |
164-273 |
Sentence |
denotes |
A series of cDNA clones for the human core protein of the large cartilage-specific proteoglycan was isolated. |
| T4 |
274-382 |
Sentence |
denotes |
Nucleotide sequencing of the clones provided over 2 kilobases of new coding sequences for the human protein. |
| T4 |
274-382 |
Sentence |
denotes |
Nucleotide sequencing of the clones provided over 2 kilobases of new coding sequences for the human protein. |
| T5 |
383-555 |
Sentence |
denotes |
Comparison with published data for cDNA clones covering the same region in rat and chick indicated that domain 8, the lectin-like domain, is highly conserved among species. |
| T5 |
383-555 |
Sentence |
denotes |
Comparison with published data for cDNA clones covering the same region in rat and chick indicated that domain 8, the lectin-like domain, is highly conserved among species. |
| T6 |
556-612 |
Sentence |
denotes |
In contrast, domain 7 is poorly conserved among species. |
| T6 |
556-612 |
Sentence |
denotes |
In contrast, domain 7 is poorly conserved among species. |
| T7 |
613-762 |
Sentence |
denotes |
Some of the cDNA clones also contained an additional structural domain between domains 7 and 8 which was not described in the rat or chick sequences. |
| T7 |
613-762 |
Sentence |
denotes |
Some of the cDNA clones also contained an additional structural domain between domains 7 and 8 which was not described in the rat or chick sequences. |
| T8 |
763-896 |
Sentence |
denotes |
The additional domain of 38 amino acids was highly homologous to epidermal growth factor (EGF)-like sequences seen in other proteins. |
| T8 |
763-896 |
Sentence |
denotes |
The additional domain of 38 amino acids was highly homologous to epidermal growth factor (EGF)-like sequences seen in other proteins. |
| T9 |
897-1063 |
Sentence |
denotes |
Because some cDNA clones contained codons for the EGF-like domain and some did not, the results suggested that the EGF-like domain underwent alternative RNA splicing. |
| T9 |
897-1063 |
Sentence |
denotes |
Because some cDNA clones contained codons for the EGF-like domain and some did not, the results suggested that the EGF-like domain underwent alternative RNA splicing. |
| T10 |
1064-1202 |
Sentence |
denotes |
To confirm alternative splicing of the EGF-like domain, RNA from cartilage cells was used as a template for the polymerase chain reaction. |
| T10 |
1064-1202 |
Sentence |
denotes |
To confirm alternative splicing of the EGF-like domain, RNA from cartilage cells was used as a template for the polymerase chain reaction. |
| T11 |
1203-1239 |
Sentence |
denotes |
Products of two sizes were obtained. |
| T11 |
1203-1239 |
Sentence |
denotes |
Products of two sizes were obtained. |
| T12 |
1240-1370 |
Sentence |
denotes |
One had the size predicted for mRNA containing the domain and the other had the size predicted for mRNA not containing the domain. |
| T12 |
1240-1370 |
Sentence |
denotes |
One had the size predicted for mRNA containing the domain and the other had the size predicted for mRNA not containing the domain. |
| T13 |
1371-1537 |
Sentence |
denotes |
Alternative splicing of an EGF-like domain may provide a mechanism of feedback regulation for both the biosynthetic activity and the proliferation of cartilage cells. |
| T13 |
1371-1537 |
Sentence |
denotes |
Alternative splicing of an EGF-like domain may provide a mechanism of feedback regulation for both the biosynthetic activity and the proliferation of cartilage cells. |