> top > projects > sentences > docs > PubMed:26795139 > annotations
sentences Home  

PubMed:26795139 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-88 Sentence denotes Serum paraoxonase-1 gene polymorphism and enzyme activity in patients with urolithiasis.
T1 0-88 Sentence denotes Serum paraoxonase-1 gene polymorphism and enzyme activity in patients with urolithiasis.
TextSentencer_T2 89-100 Sentence denotes OBJECTIVES:
T2 89-100 Sentence denotes OBJECTIVES:
TextSentencer_T3 101-268 Sentence denotes Paraoxonase-1 (PON1) is a high-density lipoprotein-associated enzyme implicated in the pathogenesis of atherosclerosis by protecting lipoproteins against peroxidation.
T3 101-268 Sentence denotes Paraoxonase-1 (PON1) is a high-density lipoprotein-associated enzyme implicated in the pathogenesis of atherosclerosis by protecting lipoproteins against peroxidation.
TextSentencer_T4 269-446 Sentence denotes PON1 has two genetic polymorphisms both due to amino acid substitution, one involving glutamine and arginine at position 192 and the other leucine and methionine at position 55.
T4 269-446 Sentence denotes PON1 has two genetic polymorphisms both due to amino acid substitution, one involving glutamine and arginine at position 192 and the other leucine and methionine at position 55.
TextSentencer_T5 447-542 Sentence denotes Recent reports suggest that nephrolithiasis and atherosclerosis share a number of risk factors.
T5 447-542 Sentence denotes Recent reports suggest that nephrolithiasis and atherosclerosis share a number of risk factors.
TextSentencer_T6 543-679 Sentence denotes Our study aimed to compare the effects of PON1 192, PON1 55 polymorphisms, and PON1 activity in patients with urolithiasis and controls.
T6 543-679 Sentence denotes Our study aimed to compare the effects of PON1 192, PON1 55 polymorphisms, and PON1 activity in patients with urolithiasis and controls.
TextSentencer_T7 680-858 Sentence denotes MATERIALS AND METHODS: PON1's arylesterase/paraoxonase activities and phenotype were determined in 158 stone forming cases (Group 1) and 138 non-stone forming controls (Group 2).
T7 680-858 Sentence denotes MATERIALS AND METHODS: PON1's arylesterase/paraoxonase activities and phenotype were determined in 158 stone forming cases (Group 1) and 138 non-stone forming controls (Group 2).
TextSentencer_T8 859-981 Sentence denotes The PON1 192 and PON1 55 polymorphisms were studied by polymerase chain reaction/restriction fragment length polymorphism.
T8 859-981 Sentence denotes The PON1 192 and PON1 55 polymorphisms were studied by polymerase chain reaction/restriction fragment length polymorphism.
TextSentencer_T9 982-990 Sentence denotes RESULTS:
T9 982-990 Sentence denotes RESULTS:
TextSentencer_T10 991-1105 Sentence denotes Paraoxonase activity was significantly lower in Group 1 than Group 2 (112 ± 31.8 vs. 208 ± 53.1 IU/L) (p < 0.001).
T10 991-1105 Sentence denotes Paraoxonase activity was significantly lower in Group 1 than Group 2 (112 ± 31.8 vs. 208 ± 53.1 IU/L) (p < 0.001).
TextSentencer_T11 1106-1169 Sentence denotes The PON1 L55M polymorphism was significantly higher in Group 1.
T11 1106-1169 Sentence denotes The PON1 L55M polymorphism was significantly higher in Group 1.
TextSentencer_T12 1170-1235 Sentence denotes The "M" allele coding for PON1 was higher in Group 1 (p < 0.001).
T12 1170-1235 Sentence denotes The "M" allele coding for PON1 was higher in Group 1 (p < 0.001).
TextSentencer_T13 1236-1359 Sentence denotes PON1 192 RR homozygotes had significantly higher PON1 activity than QR and QQ genotypes among all the patients (p < 0.001).
T13 1236-1359 Sentence denotes PON1 192 RR homozygotes had significantly higher PON1 activity than QR and QQ genotypes among all the patients (p < 0.001).
TextSentencer_T14 1360-1371 Sentence denotes CONCLUSION:
T14 1360-1371 Sentence denotes CONCLUSION:
TextSentencer_T15 1372-1481 Sentence denotes The results of our study demonstrate that the PON1 55 gene "M" allele is associated with renal stone disease.
T15 1372-1481 Sentence denotes The results of our study demonstrate that the PON1 55 gene "M" allele is associated with renal stone disease.
TextSentencer_T16 1482-1560 Sentence denotes Individuals possessing the "M" allele have a higher incidence of urolithiasis.
T16 1482-1560 Sentence denotes Individuals possessing the "M" allele have a higher incidence of urolithiasis.
TextSentencer_T17 1561-1666 Sentence denotes The results of this study provide genetic evidence that the PON1 gene may play a role in stone formation.
T17 1561-1666 Sentence denotes The results of this study provide genetic evidence that the PON1 gene may play a role in stone formation.
TextSentencer_T18 1667-1770 Sentence denotes PON1 genotype determination may provide a tool to identify individuals who are at risk of urolithiasis.
T18 1667-1770 Sentence denotes PON1 genotype determination may provide a tool to identify individuals who are at risk of urolithiasis.