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PubMed:26786498 JSONTXT 47 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-130 Sentence denotes Profiling N-Linked Oligosaccharides from IgG by High-Performance Anion-Exchange Chromatography with Pulsed Amperometric Detection.
T1 0-130 Sentence denotes Profiling N-Linked Oligosaccharides from IgG by High-Performance Anion-Exchange Chromatography with Pulsed Amperometric Detection.
T1 0-130 Sentence denotes Profiling N-Linked Oligosaccharides from IgG by High-Performance Anion-Exchange Chromatography with Pulsed Amperometric Detection.
TextSentencer_T2 131-321 Sentence denotes Understanding and characterizing protein therapeutic glycosylation is important with growing evidence that glycosylation impacts biological efficacy, pharmacokinetics, and cellular toxicity.
T2 131-321 Sentence denotes Understanding and characterizing protein therapeutic glycosylation is important with growing evidence that glycosylation impacts biological efficacy, pharmacokinetics, and cellular toxicity.
T2 131-321 Sentence denotes Understanding and characterizing protein therapeutic glycosylation is important with growing evidence that glycosylation impacts biological efficacy, pharmacokinetics, and cellular toxicity.
TextSentencer_T3 322-447 Sentence denotes Protein expression systems and reactor conditions can impact glycosylation, leading to potentially undesirable glycosylation.
T3 322-447 Sentence denotes Protein expression systems and reactor conditions can impact glycosylation, leading to potentially undesirable glycosylation.
T3 322-447 Sentence denotes Protein expression systems and reactor conditions can impact glycosylation, leading to potentially undesirable glycosylation.
TextSentencer_T4 448-549 Sentence denotes For example, high-mannose species may be present, which are atypical of human antibody glycosylation.
T4 448-549 Sentence denotes For example, high-mannose species may be present, which are atypical of human antibody glycosylation.
T4 448-549 Sentence denotes For example, high-mannose species may be present, which are atypical of human antibody glycosylation.
TextSentencer_T5 550-645 Sentence denotes Their presence in the Fc domain has been linked to increased serum clearance of IgG antibodies.
T5 550-645 Sentence denotes Their presence in the Fc domain has been linked to increased serum clearance of IgG antibodies.
T5 550-645 Sentence denotes Their presence in the Fc domain has been linked to increased serum clearance of IgG antibodies.
TextSentencer_T6 646-821 Sentence denotes High-performance anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD) is an effective tool for determining glycans present in glycoprotein therapeutics.
T6 646-821 Sentence denotes High-performance anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD) is an effective tool for determining glycans present in glycoprotein therapeutics.
T6 646-821 Sentence denotes High-performance anion-exchange chromatography with pulsed amperometric detection (HPAE-PAD) is an effective tool for determining glycans present in glycoprotein therapeutics.
TextSentencer_T7 822-895 Sentence denotes We report an improved HPAE-PAD method for IgG oligosaccharide separation.
T7 822-895 Sentence denotes We report an improved HPAE-PAD method for IgG oligosaccharide separation.
T7 822-895 Sentence denotes We report an improved HPAE-PAD method for IgG oligosaccharide separation.
TextSentencer_T8 896-1011 Sentence denotes The neutral glycans are well resolved, including separation of high-mannose species from typical human IgG glycans.
T8 896-1011 Sentence denotes The neutral glycans are well resolved, including separation of high-mannose species from typical human IgG glycans.
T8 896-1011 Sentence denotes The neutral glycans are well resolved, including separation of high-mannose species from typical human IgG glycans.
TextSentencer_T9 1012-1184 Sentence denotes Oligosaccharide identification was performed by comparison to known standards in conjunction with selective exoglycosidase digestion of both standards and released glycans.
T9 1012-1184 Sentence denotes Oligosaccharide identification was performed by comparison to known standards in conjunction with selective exoglycosidase digestion of both standards and released glycans.
T9 1012-1184 Sentence denotes Oligosaccharide identification was performed by comparison to known standards in conjunction with selective exoglycosidase digestion of both standards and released glycans.
TextSentencer_T10 1185-1358 Sentence denotes Retention times of known glycans were compared to the retention times of maltose, maltotriose, and maltotetraose standards to define a retention index value for each glycan.
T10 1185-1358 Sentence denotes Retention times of known glycans were compared to the retention times of maltose, maltotriose, and maltotetraose standards to define a retention index value for each glycan.
T10 1185-1358 Sentence denotes Retention times of known glycans were compared to the retention times of maltose, maltotriose, and maltotetraose standards to define a retention index value for each glycan.
TextSentencer_T11 1359-1494 Sentence denotes These retention indices were used to aid identification of glycans from an example monoclonal antibody sample of unknown glycosylation.
T11 1359-1494 Sentence denotes These retention indices were used to aid identification of glycans from an example monoclonal antibody sample of unknown glycosylation.
T11 1359-1494 Sentence denotes These retention indices were used to aid identification of glycans from an example monoclonal antibody sample of unknown glycosylation.
TextSentencer_T12 1495-1590 Sentence denotes Method ruggedness was evaluated across duplicate systems, analysts, and triplicate column lots.
T12 1495-1590 Sentence denotes Method ruggedness was evaluated across duplicate systems, analysts, and triplicate column lots.
T12 1495-1590 Sentence denotes Method ruggedness was evaluated across duplicate systems, analysts, and triplicate column lots.
TextSentencer_T13 1591-1769 Sentence denotes Comparing two systems with different analysts and columns, retention time precision RSDs were between 0.63 and 4.0% while retention indices precision RSDs ranged from 0.27-0.56%.
T13 1591-1769 Sentence denotes Comparing two systems with different analysts and columns, retention time precision RSDs were between 0.63 and 4.0% while retention indices precision RSDs ranged from 0.27-0.56%.
T13 1591-1769 Sentence denotes Comparing two systems with different analysts and columns, retention time precision RSDs were between 0.63 and 4.0% while retention indices precision RSDs ranged from 0.27-0.56%.
TextSentencer_T14 1770-1877 Sentence denotes The separation is orthogonal to capillary electrophoresis based separation of labeled IgG oligosaccharides.
T14 1770-1877 Sentence denotes The separation is orthogonal to capillary electrophoresis based separation of labeled IgG oligosaccharides.
T14 1770-1877 Sentence denotes The separation is orthogonal to capillary electrophoresis based separation of labeled IgG oligosaccharides.