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PubMed:26773382 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-123 Sentence denotes The acidic C-terminus of vaccinia virus I3 single-strand binding protein promotes proper assembly of DNA-protein complexes.
T1 0-123 Sentence denotes The acidic C-terminus of vaccinia virus I3 single-strand binding protein promotes proper assembly of DNA-protein complexes.
TextSentencer_T2 124-289 Sentence denotes The vaccinia virus I3L gene encodes a single-stranded DNA binding protein (SSB) that is essential for virus DNA replication and is conserved in all Chordopoxviruses.
T2 124-289 Sentence denotes The vaccinia virus I3L gene encodes a single-stranded DNA binding protein (SSB) that is essential for virus DNA replication and is conserved in all Chordopoxviruses.
TextSentencer_T3 290-384 Sentence denotes The I3 protein contains a negatively charged C-terminal tail that is a common feature of SSBs.
T3 290-384 Sentence denotes The I3 protein contains a negatively charged C-terminal tail that is a common feature of SSBs.
TextSentencer_T4 385-472 Sentence denotes Such acidic tails are critical for SSB-dependent replication, recombination and repair.
T4 385-472 Sentence denotes Such acidic tails are critical for SSB-dependent replication, recombination and repair.
TextSentencer_T5 473-644 Sentence denotes We cloned and purified variants of the I3 protein, along with a homolog from molluscum contagiosum virus, and tested how the acidic tail affected DNA-protein interactions.
T5 473-644 Sentence denotes We cloned and purified variants of the I3 protein, along with a homolog from molluscum contagiosum virus, and tested how the acidic tail affected DNA-protein interactions.
TextSentencer_T6 645-832 Sentence denotes Deleting the C terminus of I3 enhanced the affinity for single-stranded DNA cellulose and gel shift analyses showed that it also altered the migration of I3-DNA complexes in agarose gels.
T6 645-832 Sentence denotes Deleting the C terminus of I3 enhanced the affinity for single-stranded DNA cellulose and gel shift analyses showed that it also altered the migration of I3-DNA complexes in agarose gels.
TextSentencer_T7 833-945 Sentence denotes Microinjecting an antibody against I3 into vaccinia-infected cells also selectively inhibited virus replication.
T7 833-945 Sentence denotes Microinjecting an antibody against I3 into vaccinia-infected cells also selectively inhibited virus replication.
TextSentencer_T8 946-1097 Sentence denotes We suggest that this domain promotes cooperative binding of I3 to DNA in a way that would maintain an open DNA configuration around a replication site.
T8 946-1097 Sentence denotes We suggest that this domain promotes cooperative binding of I3 to DNA in a way that would maintain an open DNA configuration around a replication site.