> top > projects > sentences > docs > PubMed:26747427 > annotations

PubMed:26747427 JSONTXT 47 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-135 Sentence denotes Comparison of biological activities of human antithrombins with high-mannose or complex- type nonfucosylated N-linked oligosaccharides.
T1 0-135 Sentence denotes Comparison of biological activities of human antithrombins with high-mannose or complex- type nonfucosylated N-linked oligosaccharides.
T1 0-135 Sentence denotes Comparison of biological activities of human antithrombins with high-mannose or complex- type nonfucosylated N-linked oligosaccharides.
TextSentencer_T2 136-286 Sentence denotes The structure of the N-linked oligosaccharides attached to antithrombin (AT) has been shown to affect its anticoagulant activity and pharmacokinetics.
T2 136-286 Sentence denotes The structure of the N-linked oligosaccharides attached to antithrombin (AT) has been shown to affect its anticoagulant activity and pharmacokinetics.
T2 136-286 Sentence denotes The structure of the N-linked oligosaccharides attached to antithrombin (AT) has been shown to affect its anticoagulant activity and pharmacokinetics.
TextSentencer_T3 287-473 Sentence denotes Human AT has biantennary complex-type oligosaccharides with the unique feature of lacking a core fucose, which affects its biological activities by changing its heparin binding affinity.
T3 287-473 Sentence denotes Human AT has biantennary complex-type oligosaccharides with the unique feature of lacking a core fucose, which affects its biological activities by changing its heparin binding affinity.
T3 287-473 Sentence denotes Human AT has biantennary complex-type oligosaccharides with the unique feature of lacking a core fucose, which affects its biological activities by changing its heparin binding affinity.
TextSentencer_T4 474-614 Sentence denotes In human plasma, AT circulates as a mixture of the α-form bearing four oligosaccharides and the β-form lacking an oligosaccharide at Asn135.
T4 474-614 Sentence denotes In human plasma, AT circulates as a mixture of the α-form bearing four oligosaccharides and the β-form lacking an oligosaccharide at Asn135.
T4 474-614 Sentence denotes In human plasma, AT circulates as a mixture of the α-form bearing four oligosaccharides and the β-form lacking an oligosaccharide at Asn135.
TextSentencer_T5 615-758 Sentence denotes However, it remains unclear how the immature high-mannose-type oligosaccharides produced by mammalian cells affect biological activities of AT.
T5 615-758 Sentence denotes However, it remains unclear how the immature high-mannose-type oligosaccharides produced by mammalian cells affect biological activities of AT.
T5 615-758 Sentence denotes However, it remains unclear how the immature high-mannose-type oligosaccharides produced by mammalian cells affect biological activities of AT.
TextSentencer_T6 759-858 Sentence denotes Here, we succeeded in directly comparing the activities between the high-mannose and complex-types.
T6 759-858 Sentence denotes Here, we succeeded in directly comparing the activities between the high-mannose and complex-types.
T6 759-858 Sentence denotes Here, we succeeded in directly comparing the activities between the high-mannose and complex-types.
TextSentencer_T7 859-1015 Sentence denotes Interestingly, although there were no substantial differences in thrombin inhibitory activity, the high-mannose-type showed higher heparin binding affinity.
T7 859-1015 Sentence denotes Interestingly, although there were no substantial differences in thrombin inhibitory activity, the high-mannose-type showed higher heparin binding affinity.
T7 859-1015 Sentence denotes Interestingly, although there were no substantial differences in thrombin inhibitory activity, the high-mannose-type showed higher heparin binding affinity.
TextSentencer_T8 1016-1228 Sentence denotes The anticoagulant activities were increased by heparin and correlated with the heparin binding affinity, resulting in the strongest anticoagulant activity being displayed in the β-form with the high-mannose-type.
T8 1016-1228 Sentence denotes The anticoagulant activities were increased by heparin and correlated with the heparin binding affinity, resulting in the strongest anticoagulant activity being displayed in the β-form with the high-mannose-type.
T8 1016-1228 Sentence denotes The anticoagulant activities were increased by heparin and correlated with the heparin binding affinity, resulting in the strongest anticoagulant activity being displayed in the β-form with the high-mannose-type.
TextSentencer_T9 1229-1342 Sentence denotes In pharmacokinetic profiling, the high-mannose-type showed a much shorter plasma half-life than the complex-type.
T9 1229-1342 Sentence denotes In pharmacokinetic profiling, the high-mannose-type showed a much shorter plasma half-life than the complex-type.
T9 1229-1342 Sentence denotes In pharmacokinetic profiling, the high-mannose-type showed a much shorter plasma half-life than the complex-type.
TextSentencer_T10 1343-1539 Sentence denotes The β-form was found to have a prolonged plasma half-life compared with the α-form for the high-mannose-type; conversely, the α-form showed a longer half-life than the β-form for the complex-type.
T10 1343-1539 Sentence denotes The β-form was found to have a prolonged plasma half-life compared with the α-form for the high-mannose-type; conversely, the α-form showed a longer half-life than the β-form for the complex-type.
T10 1343-1539 Sentence denotes The β-form was found to have a prolonged plasma half-life compared with the α-form for the high-mannose-type; conversely, the α-form showed a longer half-life than the β-form for the complex-type.
TextSentencer_T11 1540-1740 Sentence denotes The present study highlights that AT physiological activities are strictly controlled not only by a core fucose at the reducing end but also by the high-mannose-type structures at the nonreducing end.
T11 1540-1740 Sentence denotes The present study highlights that AT physiological activities are strictly controlled not only by a core fucose at the reducing end but also by the high-mannose-type structures at the nonreducing end.
T11 1540-1740 Sentence denotes The present study highlights that AT physiological activities are strictly controlled not only by a core fucose at the reducing end but also by the high-mannose-type structures at the nonreducing end.
TextSentencer_T12 1741-1913 Sentence denotes The β-form with the immature high-mannose-type appears to function as a more potent anticoagulant than the AT typically found in human plasma, once it emerges in the blood.
T12 1741-1913 Sentence denotes The β-form with the immature high-mannose-type appears to function as a more potent anticoagulant than the AT typically found in human plasma, once it emerges in the blood.
T12 1741-1913 Sentence denotes The β-form with the immature high-mannose-type appears to function as a more potent anticoagulant than the AT typically found in human plasma, once it emerges in the blood.