| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T1 |
0-77 |
Sentence |
denotes |
Analysis of the structural specificity of the lactose permease toward sugars. |
| T1 |
0-77 |
Sentence |
denotes |
Analysis of the structural specificity of the lactose permease toward sugars. |
| T2 |
78-153 |
Sentence |
denotes |
The sugar specificity properties of the lactose permease were investigated. |
| T2 |
78-153 |
Sentence |
denotes |
The sugar specificity properties of the lactose permease were investigated. |
| T3 |
154-255 |
Sentence |
denotes |
Free galactose was shown to competitively inhibit the lactose permease yielding a Ki value of 7.4 mM. |
| T3 |
154-255 |
Sentence |
denotes |
Free galactose was shown to competitively inhibit the lactose permease yielding a Ki value of 7.4 mM. |
| T4 |
256-332 |
Sentence |
denotes |
This value was severalfold higher than the observed Km for lactose (1.3 mM). |
| T4 |
256-332 |
Sentence |
denotes |
This value was severalfold higher than the observed Km for lactose (1.3 mM). |
| T5 |
333-424 |
Sentence |
denotes |
A variety of other monosaccharides also showed significant inhibition of lactose transport. |
| T5 |
333-424 |
Sentence |
denotes |
A variety of other monosaccharides also showed significant inhibition of lactose transport. |
| T6 |
425-596 |
Sentence |
denotes |
With regard to -OH groups along the galactose ring it appears that the relative importance is OH-3 greater than OH-4 greater than OH-6 greater than OH-2 greater than OH-1. |
| T6 |
425-596 |
Sentence |
denotes |
With regard to -OH groups along the galactose ring it appears that the relative importance is OH-3 greater than OH-4 greater than OH-6 greater than OH-2 greater than OH-1. |
| T7 |
597-729 |
Sentence |
denotes |
In general, galactosides with alpha-linkages exhibited significantly higher affinities compared with their beta-linked counterparts. |
| T7 |
597-729 |
Sentence |
denotes |
In general, galactosides with alpha-linkages exhibited significantly higher affinities compared with their beta-linked counterparts. |
| T8 |
730-862 |
Sentence |
denotes |
An optimal size for the aglycone portion of the galactoside was reached with aglycones containing hexose residues or a benzene ring. |
| T8 |
730-862 |
Sentence |
denotes |
An optimal size for the aglycone portion of the galactoside was reached with aglycones containing hexose residues or a benzene ring. |
| T9 |
863-1042 |
Sentence |
denotes |
The preferred size of the aglycone appears to be hexose, benzene ring greater than methyl group greater than no aglycone much greater than disaccharide greater than trisaccharide. |
| T9 |
863-1042 |
Sentence |
denotes |
The preferred size of the aglycone appears to be hexose, benzene ring greater than methyl group greater than no aglycone much greater than disaccharide greater than trisaccharide. |
| T10 |
1043-1188 |
Sentence |
denotes |
However, neither the specific structure of the aglycone nor its relative hydrophobicity appeared to be important factors in permease recognition. |
| T10 |
1043-1188 |
Sentence |
denotes |
However, neither the specific structure of the aglycone nor its relative hydrophobicity appeared to be important factors in permease recognition. |
| T11 |
1189-1434 |
Sentence |
denotes |
For example, the hydrophobic beta-nitrophenyl-galactosides had lower affinities compared with lactose (a beta-galactoside), whereas the alpha-nitrophenylgalactosides generally had higher affinities compared with melibiose (an alpha-galactoside). |
| T11 |
1189-1434 |
Sentence |
denotes |
For example, the hydrophobic beta-nitrophenyl-galactosides had lower affinities compared with lactose (a beta-galactoside), whereas the alpha-nitrophenylgalactosides generally had higher affinities compared with melibiose (an alpha-galactoside). |
| T12 |
1435-1551 |
Sentence |
denotes |
In addition, no consistent preference was seen when considering the location of the nitro group on the benzene ring. |
| T12 |
1435-1551 |
Sentence |
denotes |
In addition, no consistent preference was seen when considering the location of the nitro group on the benzene ring. |
| T13 |
1552-1655 |
Sentence |
denotes |
From this work, a model is presented which depicts the binding of galactosides to the lactose permease. |
| T13 |
1552-1655 |
Sentence |
denotes |
From this work, a model is presented which depicts the binding of galactosides to the lactose permease. |