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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-64 Sentence denotes Glycosaminoglycans affect heparanase location in CHO cell lines.
T1 0-64 Sentence denotes Glycosaminoglycans affect heparanase location in CHO cell lines.
T1 0-64 Sentence denotes Glycosaminoglycans affect heparanase location in CHO cell lines.
TextSentencer_T2 65-134 Sentence denotes Glycosaminoglycans (GAG) play a ubiquitous role in tissues and cells.
T2 65-134 Sentence denotes Glycosaminoglycans (GAG) play a ubiquitous role in tissues and cells.
T2 65-134 Sentence denotes Glycosaminoglycans (GAG) play a ubiquitous role in tissues and cells.
TextSentencer_T3 135-253 Sentence denotes In eukaryotic cells, heparan sulfate (HS) is initially degraded by an endo-β-glucuronidase called heparanase-1 (HPSE).
T3 135-253 Sentence denotes In eukaryotic cells, heparan sulfate (HS) is initially degraded by an endo-β-glucuronidase called heparanase-1 (HPSE).
T3 135-253 Sentence denotes In eukaryotic cells, heparan sulfate (HS) is initially degraded by an endo-β-glucuronidase called heparanase-1 (HPSE).
TextSentencer_T4 254-422 Sentence denotes HS oligosaccharides generated by the action of HPSE intensify the activity of signaling molecules, activating inflammatory response, tumor metastasis, and angiogenesis.
T4 254-422 Sentence denotes HS oligosaccharides generated by the action of HPSE intensify the activity of signaling molecules, activating inflammatory response, tumor metastasis, and angiogenesis.
T4 254-422 Sentence denotes HS oligosaccharides generated by the action of HPSE intensify the activity of signaling molecules, activating inflammatory response, tumor metastasis, and angiogenesis.
TextSentencer_T5 423-580 Sentence denotes The aim of the present study was to understand if sulfated GAG could modulate HPSE, since the mechanisms that regulate HPSE have not been completely defined.
T5 423-580 Sentence denotes The aim of the present study was to understand if sulfated GAG could modulate HPSE, since the mechanisms that regulate HPSE have not been completely defined.
T5 423-580 Sentence denotes The aim of the present study was to understand if sulfated GAG could modulate HPSE, since the mechanisms that regulate HPSE have not been completely defined.
TextSentencer_T6 581-755 Sentence denotes CHO-K1 cells were treated with 4-methylumbelliferone (4-MU) and sodium chlorate, to promote total inhibition of GAG synthesis, and reduce the sulfation pattern, respectively.
T6 581-755 Sentence denotes CHO-K1 cells were treated with 4-methylumbelliferone (4-MU) and sodium chlorate, to promote total inhibition of GAG synthesis, and reduce the sulfation pattern, respectively.
T6 581-755 Sentence denotes CHO-K1 cells were treated with 4-methylumbelliferone (4-MU) and sodium chlorate, to promote total inhibition of GAG synthesis, and reduce the sulfation pattern, respectively.
TextSentencer_T7 756-889 Sentence denotes The GAG profile of the wild CHO-K1 cells and CHO-745, deficient in xylosyltransferase, was determined after [(35)S]-sulfate labeling.
T7 756-889 Sentence denotes The GAG profile of the wild CHO-K1 cells and CHO-745, deficient in xylosyltransferase, was determined after [(35)S]-sulfate labeling.
T7 756-889 Sentence denotes The GAG profile of the wild CHO-K1 cells and CHO-745, deficient in xylosyltransferase, was determined after [(35)S]-sulfate labeling.
TextSentencer_T8 890-974 Sentence denotes HPSE expression was determined via real-time quantitative polymerase chain reaction.
T8 890-974 Sentence denotes HPSE expression was determined via real-time quantitative polymerase chain reaction.
T8 890-974 Sentence denotes HPSE expression was determined via real-time quantitative polymerase chain reaction.
TextSentencer_T9 975-1086 Sentence denotes Total ablation of GAG with 4-MU in CHO-K1 inhibited HPSE expression, while the lack of sulfation had no effect.
T9 975-1086 Sentence denotes Total ablation of GAG with 4-MU in CHO-K1 inhibited HPSE expression, while the lack of sulfation had no effect.
T9 975-1086 Sentence denotes Total ablation of GAG with 4-MU in CHO-K1 inhibited HPSE expression, while the lack of sulfation had no effect.
TextSentencer_T10 1087-1155 Sentence denotes Interestingly, 4-MU had no effect in CHO-745 cells for these assays.
T10 1087-1155 Sentence denotes Interestingly, 4-MU had no effect in CHO-745 cells for these assays.
T10 1087-1155 Sentence denotes Interestingly, 4-MU had no effect in CHO-745 cells for these assays.
TextSentencer_T11 1156-1370 Sentence denotes In addition, a different enzyme location was observed in CHO-K1 wild-type cells, which presents HPSE mainly in the extracellular matrix, in comparison with the CHO-745 mutant cells, which is found in the cytoplasm.
T11 1156-1370 Sentence denotes In addition, a different enzyme location was observed in CHO-K1 wild-type cells, which presents HPSE mainly in the extracellular matrix, in comparison with the CHO-745 mutant cells, which is found in the cytoplasm.
T11 1156-1370 Sentence denotes In addition, a different enzyme location was observed in CHO-K1 wild-type cells, which presents HPSE mainly in the extracellular matrix, in comparison with the CHO-745 mutant cells, which is found in the cytoplasm.
TextSentencer_T12 1371-1477 Sentence denotes In view of our results, we can conclude that GAG are essential modulators of HPSE expression and location.
T12 1371-1477 Sentence denotes In view of our results, we can conclude that GAG are essential modulators of HPSE expression and location.
T12 1371-1477 Sentence denotes In view of our results, we can conclude that GAG are essential modulators of HPSE expression and location.
TextSentencer_T13 1478-1563 Sentence denotes Therefore, GAG profile could impact cell behavior mediated by the regulation of HPSE.
T13 1478-1563 Sentence denotes Therefore, GAG profile could impact cell behavior mediated by the regulation of HPSE.
T13 1478-1563 Sentence denotes Therefore, GAG profile could impact cell behavior mediated by the regulation of HPSE.