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PubMed:26022516 JSONTXT 62 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-34 Sentence denotes Human sialic acid acetyl esterase:
T1 0-34 Sentence denotes Human sialic acid acetyl esterase:
T1 0-34 Sentence denotes Human sialic acid acetyl esterase:
TextSentencer_T2 35-87 Sentence denotes Towards a better understanding of a puzzling enzyme.
T2 35-87 Sentence denotes Towards a better understanding of a puzzling enzyme.
T2 35-87 Sentence denotes Towards a better understanding of a puzzling enzyme.
TextSentencer_T3 88-207 Sentence denotes Sialic acid acetyl esterase (SIAE) removes acetyl moieties from the hydroxyl groups in position 9 and 4 of sialic acid.
T3 88-207 Sentence denotes Sialic acid acetyl esterase (SIAE) removes acetyl moieties from the hydroxyl groups in position 9 and 4 of sialic acid.
T3 88-207 Sentence denotes Sialic acid acetyl esterase (SIAE) removes acetyl moieties from the hydroxyl groups in position 9 and 4 of sialic acid.
TextSentencer_T4 208-279 Sentence denotes Recently, a dispute has been opened on its association to autoimmunity.
T4 208-279 Sentence denotes Recently, a dispute has been opened on its association to autoimmunity.
T4 208-279 Sentence denotes Recently, a dispute has been opened on its association to autoimmunity.
TextSentencer_T5 280-516 Sentence denotes In order to get new insights on human SIAE biology and to clarify its seemingly contradictory molecular properties, we combined in silico characterization, phylogenetic analysis and homology modeling with cellular studies in COS7 cells.
T5 280-516 Sentence denotes In order to get new insights on human SIAE biology and to clarify its seemingly contradictory molecular properties, we combined in silico characterization, phylogenetic analysis and homology modeling with cellular studies in COS7 cells.
T5 280-516 Sentence denotes In order to get new insights on human SIAE biology and to clarify its seemingly contradictory molecular properties, we combined in silico characterization, phylogenetic analysis and homology modeling with cellular studies in COS7 cells.
TextSentencer_T6 517-673 Sentence denotes Genomic and phylogenetic analysis revealed that in most tissues only the "long" isoform, originally referred to lysosomal sialic acid esterase, is detected.
T6 517-673 Sentence denotes Genomic and phylogenetic analysis revealed that in most tissues only the "long" isoform, originally referred to lysosomal sialic acid esterase, is detected.
T6 517-673 Sentence denotes Genomic and phylogenetic analysis revealed that in most tissues only the "long" isoform, originally referred to lysosomal sialic acid esterase, is detected.
TextSentencer_T7 674-820 Sentence denotes Using the homology modeling approach, we predicted a model of SIAE 3D structure, which fulfills the topological features of SGNH-hydrolase family.
T7 674-820 Sentence denotes Using the homology modeling approach, we predicted a model of SIAE 3D structure, which fulfills the topological features of SGNH-hydrolase family.
T7 674-820 Sentence denotes Using the homology modeling approach, we predicted a model of SIAE 3D structure, which fulfills the topological features of SGNH-hydrolase family.
TextSentencer_T8 821-947 Sentence denotes In addition, the model and site-directed mutagenesis experiments allowed the definition of the residues involved in catalysis.
T8 821-947 Sentence denotes In addition, the model and site-directed mutagenesis experiments allowed the definition of the residues involved in catalysis.
T8 821-947 Sentence denotes In addition, the model and site-directed mutagenesis experiments allowed the definition of the residues involved in catalysis.
TextSentencer_T9 948-1097 Sentence denotes SIAE transient expression revealed that the protein is glycosylated and is active in vitro as an esterase with a pH optimum corresponding to 8.4-8.5.
T9 948-1097 Sentence denotes SIAE transient expression revealed that the protein is glycosylated and is active in vitro as an esterase with a pH optimum corresponding to 8.4-8.5.
T9 948-1097 Sentence denotes SIAE transient expression revealed that the protein is glycosylated and is active in vitro as an esterase with a pH optimum corresponding to 8.4-8.5.
TextSentencer_T10 1098-1232 Sentence denotes Moreover, glycosylation influences the biological activity of the enzyme and is essential for release of SIAE into the culture medium.
T10 1098-1232 Sentence denotes Moreover, glycosylation influences the biological activity of the enzyme and is essential for release of SIAE into the culture medium.
T10 1098-1232 Sentence denotes Moreover, glycosylation influences the biological activity of the enzyme and is essential for release of SIAE into the culture medium.
TextSentencer_T11 1233-1406 Sentence denotes According to these findings, co-localization experiments demonstrated the presence of SIAE in membranous structures corresponding to endoplasmic reticulum and Golgi complex.
T11 1233-1406 Sentence denotes According to these findings, co-localization experiments demonstrated the presence of SIAE in membranous structures corresponding to endoplasmic reticulum and Golgi complex.
T11 1233-1406 Sentence denotes According to these findings, co-localization experiments demonstrated the presence of SIAE in membranous structures corresponding to endoplasmic reticulum and Golgi complex.
TextSentencer_T12 1407-1585 Sentence denotes Thus, at least in COS7 cells, SIAE behaves as a typical secreted enzyme, subjected to glycosylation and located along the classical secretory route or in the extracellular space.
T12 1407-1585 Sentence denotes Thus, at least in COS7 cells, SIAE behaves as a typical secreted enzyme, subjected to glycosylation and located along the classical secretory route or in the extracellular space.
T12 1407-1585 Sentence denotes Thus, at least in COS7 cells, SIAE behaves as a typical secreted enzyme, subjected to glycosylation and located along the classical secretory route or in the extracellular space.
TextSentencer_T13 1586-1755 Sentence denotes In these environments, the enzyme could act on 9-O-acetylated sialic acid residues, contributing to the fine-tuning of the various functions played by this acidic sugar.
T13 1586-1755 Sentence denotes In these environments, the enzyme could act on 9-O-acetylated sialic acid residues, contributing to the fine-tuning of the various functions played by this acidic sugar.
T13 1586-1755 Sentence denotes In these environments, the enzyme could act on 9-O-acetylated sialic acid residues, contributing to the fine-tuning of the various functions played by this acidic sugar.