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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-134 Sentence denotes Expression of stage-specific embryonic antigen-4 (SSEA-4) defines spontaneous loss of epithelial phenotype in human solid tumor cells.
T1 0-134 Sentence denotes Expression of stage-specific embryonic antigen-4 (SSEA-4) defines spontaneous loss of epithelial phenotype in human solid tumor cells.
T1 0-134 Sentence denotes Expression of stage-specific embryonic antigen-4 (SSEA-4) defines spontaneous loss of epithelial phenotype in human solid tumor cells.
TextSentencer_T2 135-285 Sentence denotes Stage-specific embryonic antigen-4 (SSEA-4) is a glycosphingolipid, which is overexpressed in some cancers and has been linked to disease progression.
T2 135-285 Sentence denotes Stage-specific embryonic antigen-4 (SSEA-4) is a glycosphingolipid, which is overexpressed in some cancers and has been linked to disease progression.
T2 135-285 Sentence denotes Stage-specific embryonic antigen-4 (SSEA-4) is a glycosphingolipid, which is overexpressed in some cancers and has been linked to disease progression.
TextSentencer_T3 286-398 Sentence denotes However, little is known about the functions of SSEA-4 and the characteristics of SSEA-4 expressing tumor cells.
T3 286-398 Sentence denotes However, little is known about the functions of SSEA-4 and the characteristics of SSEA-4 expressing tumor cells.
T3 286-398 Sentence denotes However, little is known about the functions of SSEA-4 and the characteristics of SSEA-4 expressing tumor cells.
TextSentencer_T4 399-530 Sentence denotes Our studies identified SSEA-4 expression on a subpopulation of cells in many solid tumor cell lines but not in leukemic cell lines.
T4 399-530 Sentence denotes Our studies identified SSEA-4 expression on a subpopulation of cells in many solid tumor cell lines but not in leukemic cell lines.
T4 399-530 Sentence denotes Our studies identified SSEA-4 expression on a subpopulation of cells in many solid tumor cell lines but not in leukemic cell lines.
TextSentencer_T5 531-739 Sentence denotes Fluorescence-activated cell sorting-sorted SSEA-4(+) prostate cancer cells formed fibroblast-like colonies with limited cell-cell contacts, whereas SSEA-4(-) cells formed cobblestone-like epithelial colonies.
T5 531-739 Sentence denotes Fluorescence-activated cell sorting-sorted SSEA-4(+) prostate cancer cells formed fibroblast-like colonies with limited cell-cell contacts, whereas SSEA-4(-) cells formed cobblestone-like epithelial colonies.
T5 531-739 Sentence denotes Fluorescence-activated cell sorting-sorted SSEA-4(+) prostate cancer cells formed fibroblast-like colonies with limited cell-cell contacts, whereas SSEA-4(-) cells formed cobblestone-like epithelial colonies.
TextSentencer_T6 740-841 Sentence denotes Only colonies derived from SSEA-4(+) cells were enriched for pluripotent embryonic stem cell markers.
T6 740-841 Sentence denotes Only colonies derived from SSEA-4(+) cells were enriched for pluripotent embryonic stem cell markers.
T6 740-841 Sentence denotes Only colonies derived from SSEA-4(+) cells were enriched for pluripotent embryonic stem cell markers.
TextSentencer_T7 842-1005 Sentence denotes Moreover, major epithelial cell-associated markers Claudin-7, E-cadherin, ESRP1 and GRHL2 were down-regulated in the SSEA-4(+) fraction of DU145 and HCT-116 cells.
T7 842-1005 Sentence denotes Moreover, major epithelial cell-associated markers Claudin-7, E-cadherin, ESRP1 and GRHL2 were down-regulated in the SSEA-4(+) fraction of DU145 and HCT-116 cells.
T7 842-1005 Sentence denotes Moreover, major epithelial cell-associated markers Claudin-7, E-cadherin, ESRP1 and GRHL2 were down-regulated in the SSEA-4(+) fraction of DU145 and HCT-116 cells.
TextSentencer_T8 1006-1134 Sentence denotes Similar to cell lines, SSEA-4(+) primary prostate tumor cells also showed down-regulation of epithelial cell-associated markers.
T8 1006-1134 Sentence denotes Similar to cell lines, SSEA-4(+) primary prostate tumor cells also showed down-regulation of epithelial cell-associated markers.
T8 1006-1134 Sentence denotes Similar to cell lines, SSEA-4(+) primary prostate tumor cells also showed down-regulation of epithelial cell-associated markers.
TextSentencer_T9 1135-1245 Sentence denotes In addition, they showed up-regulation of epithelial-to-mesenchymal transition as well as mesenchymal markers.
T9 1135-1245 Sentence denotes In addition, they showed up-regulation of epithelial-to-mesenchymal transition as well as mesenchymal markers.
T9 1135-1245 Sentence denotes In addition, they showed up-regulation of epithelial-to-mesenchymal transition as well as mesenchymal markers.
TextSentencer_T10 1246-1462 Sentence denotes Furthermore, SSEA-4(+) cells escape from adhesive colonies spontaneously and form invadopodia-like migratory structures, in which SSEA-4, cortactin as well as active pPI3K, pAkt and pSrc are enriched and colocalized.
T10 1246-1462 Sentence denotes Furthermore, SSEA-4(+) cells escape from adhesive colonies spontaneously and form invadopodia-like migratory structures, in which SSEA-4, cortactin as well as active pPI3K, pAkt and pSrc are enriched and colocalized.
T10 1246-1462 Sentence denotes Furthermore, SSEA-4(+) cells escape from adhesive colonies spontaneously and form invadopodia-like migratory structures, in which SSEA-4, cortactin as well as active pPI3K, pAkt and pSrc are enriched and colocalized.
TextSentencer_T11 1463-1642 Sentence denotes Finally, SSEA-4(+) cells displayed strong tumorigenic ability and stable knockdown of SSEA-4 synthesis resulted in decreased cellular adhesion to different extracellular matrices.
T11 1463-1642 Sentence denotes Finally, SSEA-4(+) cells displayed strong tumorigenic ability and stable knockdown of SSEA-4 synthesis resulted in decreased cellular adhesion to different extracellular matrices.
T11 1463-1642 Sentence denotes Finally, SSEA-4(+) cells displayed strong tumorigenic ability and stable knockdown of SSEA-4 synthesis resulted in decreased cellular adhesion to different extracellular matrices.
TextSentencer_T12 1643-1762 Sentence denotes In conclusion, we introduce SSEA-4 as a novel marker to identify heterogeneous, invasive subpopulations of tumor cells.
T12 1643-1762 Sentence denotes In conclusion, we introduce SSEA-4 as a novel marker to identify heterogeneous, invasive subpopulations of tumor cells.
T12 1643-1762 Sentence denotes In conclusion, we introduce SSEA-4 as a novel marker to identify heterogeneous, invasive subpopulations of tumor cells.
TextSentencer_T13 1763-2026 Sentence denotes Moreover, increased cell-surface SSEA-4 expression is associated with the loss of cell-cell interactions and the gain of a migratory phenotype, suggesting an important role of SSEA-4 in cancer invasion by influencing cellular adhesion to the extracellular matrix.
T13 1763-2026 Sentence denotes Moreover, increased cell-surface SSEA-4 expression is associated with the loss of cell-cell interactions and the gain of a migratory phenotype, suggesting an important role of SSEA-4 in cancer invasion by influencing cellular adhesion to the extracellular matrix.
T13 1763-2026 Sentence denotes Moreover, increased cell-surface SSEA-4 expression is associated with the loss of cell-cell interactions and the gain of a migratory phenotype, suggesting an important role of SSEA-4 in cancer invasion by influencing cellular adhesion to the extracellular matrix.