| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-107 |
Sentence |
denotes |
Decapping protein 1 phosphorylation modulates IL-8 expression during respiratory syncytial virus infection. |
| T1 |
0-107 |
Sentence |
denotes |
Decapping protein 1 phosphorylation modulates IL-8 expression during respiratory syncytial virus infection. |
| TextSentencer_T2 |
108-231 |
Sentence |
denotes |
Respiratory syncytial virus (RSV) is a negative-strand RNA virus that is an important cause of bronchiolitis and pneumonia. |
| T2 |
108-231 |
Sentence |
denotes |
Respiratory syncytial virus (RSV) is a negative-strand RNA virus that is an important cause of bronchiolitis and pneumonia. |
| TextSentencer_T3 |
232-528 |
Sentence |
denotes |
We investigated the effect of RSV infection on the expression patterns of cellular proteins involved in regulating mRNA translation and degradation, and found that a processing-body protein involved in mRNA degradation, decapping protein 1a (DCP1), was phosphorylated rapidly following infection. |
| T3 |
232-528 |
Sentence |
denotes |
We investigated the effect of RSV infection on the expression patterns of cellular proteins involved in regulating mRNA translation and degradation, and found that a processing-body protein involved in mRNA degradation, decapping protein 1a (DCP1), was phosphorylated rapidly following infection. |
| TextSentencer_T4 |
529-696 |
Sentence |
denotes |
UV-inactivated and sucrose-purified RSV were sufficient to mediate DCP1 phosphorylation, indicating that it occurs as a consequence of an early event in RSV infection. |
| T4 |
529-696 |
Sentence |
denotes |
UV-inactivated and sucrose-purified RSV were sufficient to mediate DCP1 phosphorylation, indicating that it occurs as a consequence of an early event in RSV infection. |
| TextSentencer_T5 |
697-811 |
Sentence |
denotes |
Analysis using kinase inhibitors showed that RSV-induced DCP1 phosphorylation occurred through the ERK1/2 pathway. |
| T5 |
697-811 |
Sentence |
denotes |
Analysis using kinase inhibitors showed that RSV-induced DCP1 phosphorylation occurred through the ERK1/2 pathway. |
| TextSentencer_T6 |
812-901 |
Sentence |
denotes |
The DCP1 phosphorylation sites were limited to serine 315, serine 319, and threonine 321. |
| T6 |
812-901 |
Sentence |
denotes |
The DCP1 phosphorylation sites were limited to serine 315, serine 319, and threonine 321. |
| TextSentencer_T7 |
902-1071 |
Sentence |
denotes |
Overexpression of wt DCP1 led to a decrease in RSV-induced IL-8 production, but this effect was abrogated in cells overexpressing phosphorylation-deficient DCP1 mutants. |
| T7 |
902-1071 |
Sentence |
denotes |
Overexpression of wt DCP1 led to a decrease in RSV-induced IL-8 production, but this effect was abrogated in cells overexpressing phosphorylation-deficient DCP1 mutants. |
| TextSentencer_T8 |
1072-1175 |
Sentence |
denotes |
These results suggest that DCP1 phosphorylation modulates the host chemokine response to RSV infection. |
| T8 |
1072-1175 |
Sentence |
denotes |
These results suggest that DCP1 phosphorylation modulates the host chemokine response to RSV infection. |