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PubMed:25452134 / 122-1892 JSONTXT 12 Projects

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Id Subject Object Predicate Lexical cue
T3 0-111 Sentence denotes Caenorhabditis elegans can be infected by a plethora of pathogens, most of them are also pathogenic for humans.
T3 0-111 Sentence denotes Caenorhabditis elegans can be infected by a plethora of pathogens, most of them are also pathogenic for humans.
T4 112-310 Sentence denotes Consequently, the nematode has emerged as a powerful surrogate host to model microbial human infectious diseases in a non-vertebrate, for the study of innate immunity and host-pathogen interactions.
T4 112-310 Sentence denotes Consequently, the nematode has emerged as a powerful surrogate host to model microbial human infectious diseases in a non-vertebrate, for the study of innate immunity and host-pathogen interactions.
T5 311-392 Sentence denotes Signaling cascades are well investigated that face bacterial or fungal pathogens.
T5 311-392 Sentence denotes Signaling cascades are well investigated that face bacterial or fungal pathogens.
T6 393-662 Sentence denotes We analyzed the downstream processes of these cascades, i.e. the differential expression of effector and regulatory molecules due to a microbial challenge with a pathogenic strain of the bacterium Bacillus thuringiensis (Bt) in comparison to a non-pathogenic Bt strain.
T6 393-662 Sentence denotes We analyzed the downstream processes of these cascades, i.e. the differential expression of effector and regulatory molecules due to a microbial challenge with a pathogenic strain of the bacterium Bacillus thuringiensis (Bt) in comparison to a non-pathogenic Bt strain.
T7 663-791 Sentence denotes The protein abundance profile of the nematode was studied by quantitative proteomics using iTRAQ labeling and 2D-LC-MS analysis.
T7 663-791 Sentence denotes The protein abundance profile of the nematode was studied by quantitative proteomics using iTRAQ labeling and 2D-LC-MS analysis.
T8 792-1031 Sentence denotes We developed (i) a novel method for the preparation of defined C. elegans samples; (ii) a pooling strategy for fractions in 2D-LC separation schemes; and (iii) an isobaric labeling scheme reducing the number of necessary LC-MS experiments.
T8 792-1031 Sentence denotes We developed (i) a novel method for the preparation of defined C. elegans samples; (ii) a pooling strategy for fractions in 2D-LC separation schemes; and (iii) an isobaric labeling scheme reducing the number of necessary LC-MS experiments.
T9 1032-1255 Sentence denotes More than 3,600 proteins were quantified, 288 of which showed altered abundances, implicating protein classes such as lectins, lysozymes, and transthyretin-like proteins to be involved in the nematode innate immune defense.
T9 1032-1255 Sentence denotes More than 3,600 proteins were quantified, 288 of which showed altered abundances, implicating protein classes such as lectins, lysozymes, and transthyretin-like proteins to be involved in the nematode innate immune defense.
T10 1256-1376 Sentence denotes A number of gene products previously only identified by transcriptomic profiling could be verified at the protein level.
T10 1256-1376 Sentence denotes A number of gene products previously only identified by transcriptomic profiling could be verified at the protein level.
T11 1377-1564 Sentence denotes Moreover, several other protein classes such as proteases, proteins related to autophagy and apoptosis, structural proteins, and proteins involved in chromatin organization were detected.
T11 1377-1564 Sentence denotes Moreover, several other protein classes such as proteases, proteins related to autophagy and apoptosis, structural proteins, and proteins involved in chromatin organization were detected.
T12 1565-1770 Sentence denotes The results provide an overview of the physiological response towards a pathogen at protein level in the important model organism C. elegans, giving insights into highly complex host-pathogen interactions.
T12 1565-1770 Sentence denotes The results provide an overview of the physiological response towards a pathogen at protein level in the important model organism C. elegans, giving insights into highly complex host-pathogen interactions.