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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-134 Sentence denotes Differential proteomic analysis of umbilical artery tissue from preeclampsia patients, using iTRAQ isobaric tags and 2D nano LC-MS/MS.
T1 0-134 Sentence denotes Differential proteomic analysis of umbilical artery tissue from preeclampsia patients, using iTRAQ isobaric tags and 2D nano LC-MS/MS.
TextSentencer_T2 135-146 Sentence denotes UNLABELLED:
T2 135-146 Sentence denotes UNLABELLED:
TextSentencer_T3 147-265 Sentence denotes Epidemiological studies suggest that the impact of preeclampsia does not only affect the mother but also the children.
T3 147-265 Sentence denotes Epidemiological studies suggest that the impact of preeclampsia does not only affect the mother but also the children.
TextSentencer_T4 266-414 Sentence denotes We know that adverse events in utero may predispose individuals to premature cardiovascular disease in adulthood, but we do not know the mechanisms.
T4 266-414 Sentence denotes We know that adverse events in utero may predispose individuals to premature cardiovascular disease in adulthood, but we do not know the mechanisms.
TextSentencer_T5 415-625 Sentence denotes To gain insights into the mechanisms of cardiovascular dysfunction in the offspring of preeclampsia, we employed a global stable isotope labeled profiling strategy using iTRAQ reagents, followed by 2D-LC-MS/MS.
T5 415-625 Sentence denotes To gain insights into the mechanisms of cardiovascular dysfunction in the offspring of preeclampsia, we employed a global stable isotope labeled profiling strategy using iTRAQ reagents, followed by 2D-LC-MS/MS.
TextSentencer_T6 626-703 Sentence denotes We identified 1521 non-redundant proteins, and 1496 of these were quantified.
T6 626-703 Sentence denotes We identified 1521 non-redundant proteins, and 1496 of these were quantified.
TextSentencer_T7 704-856 Sentence denotes Further analysis identified 53 differentially expressed proteins in umbilical artery; 22 proteins were up-regulated and 31 proteins were down-regulated.
T7 704-856 Sentence denotes Further analysis identified 53 differentially expressed proteins in umbilical artery; 22 proteins were up-regulated and 31 proteins were down-regulated.
TextSentencer_T8 857-1034 Sentence denotes K-means clustering analysis showed that there was a specific protein expression profile in the umbilical artery which could distinguish between normal and preeclampsia patients.
T8 857-1034 Sentence denotes K-means clustering analysis showed that there was a specific protein expression profile in the umbilical artery which could distinguish between normal and preeclampsia patients.
TextSentencer_T9 1035-1224 Sentence denotes These 53 proteins were analyzed by Ingenuity Pathway Analysis (IPA) and were found to play important roles in the angiogenesis, vasculogenesis, and development of the cardiovascular system.
T9 1035-1224 Sentence denotes These 53 proteins were analyzed by Ingenuity Pathway Analysis (IPA) and were found to play important roles in the angiogenesis, vasculogenesis, and development of the cardiovascular system.
TextSentencer_T10 1225-1401 Sentence denotes In addition, the differential expression of three cardiovascular relative proteins (aldose reductase, fibronectin-1, fibrillin-1) was independently verified using western blot.
T10 1225-1401 Sentence denotes In addition, the differential expression of three cardiovascular relative proteins (aldose reductase, fibronectin-1, fibrillin-1) was independently verified using western blot.
TextSentencer_T11 1402-1526 Sentence denotes These results may supply new insights into the mechanisms of vascular dysfunction in the offspring of preeclampsia patients.
T11 1402-1526 Sentence denotes These results may supply new insights into the mechanisms of vascular dysfunction in the offspring of preeclampsia patients.
TextSentencer_T12 1527-1551 Sentence denotes BIOLOGICAL SIGNIFICANCE:
T12 1527-1551 Sentence denotes BIOLOGICAL SIGNIFICANCE:
TextSentencer_T13 1552-1758 Sentence denotes Increasing evidence suggests that the children who were exposed to preeclampsia in utero have an increased cardiovascular risk, and vascular dysfunction has been found in some children born of preeclampsia.
T13 1552-1758 Sentence denotes Increasing evidence suggests that the children who were exposed to preeclampsia in utero have an increased cardiovascular risk, and vascular dysfunction has been found in some children born of preeclampsia.
TextSentencer_T14 1759-1806 Sentence denotes However, the mechanism remains largely unknown.
T14 1759-1806 Sentence denotes However, the mechanism remains largely unknown.
TextSentencer_T15 1807-1899 Sentence denotes In this study, we identified 1521 non-redundant proteins, and 1496 of these were quantified.
T15 1807-1899 Sentence denotes In this study, we identified 1521 non-redundant proteins, and 1496 of these were quantified.
TextSentencer_T16 1900-2083 Sentence denotes Further analysis identified 53 differentially expressed proteins in the umbilical artery from preeclampsia patients; 22 proteins were up-regulated and 31 proteins were down-regulated.
T16 1900-2083 Sentence denotes Further analysis identified 53 differentially expressed proteins in the umbilical artery from preeclampsia patients; 22 proteins were up-regulated and 31 proteins were down-regulated.
TextSentencer_T17 2084-2209 Sentence denotes Some of these differentially expressed proteins have been shown to play important roles in cardiovascular system development.
T17 2084-2209 Sentence denotes Some of these differentially expressed proteins have been shown to play important roles in cardiovascular system development.
TextSentencer_T18 2210-2431 Sentence denotes Our results provide new insights into the potential mechanisms underlying the changed blood pressure of offspring of mothers with preeclampsia, and, the elevation of their risk of cardiovascular abnormality in later life.
T18 2210-2431 Sentence denotes Our results provide new insights into the potential mechanisms underlying the changed blood pressure of offspring of mothers with preeclampsia, and, the elevation of their risk of cardiovascular abnormality in later life.