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PubMed:25213700 JSONTXT 7 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-94 Sentence denotes Esophageal cancer stem cells express PLGF to increase cancer invasion through MMP9 activation.
T1 0-94 Sentence denotes Esophageal cancer stem cells express PLGF to increase cancer invasion through MMP9 activation.
TextSentencer_T2 95-196 Sentence denotes Cancer stem cells (CSCs) are a distinct population in tumors and cause cancer relapse and metastasis.
T2 95-196 Sentence denotes Cancer stem cells (CSCs) are a distinct population in tumors and cause cancer relapse and metastasis.
TextSentencer_T3 197-300 Sentence denotes Thus, treating CSCs are believed to be potential to cure rapidly growing and highly metastatic cancers.
T3 197-300 Sentence denotes Thus, treating CSCs are believed to be potential to cure rapidly growing and highly metastatic cancers.
TextSentencer_T4 301-364 Sentence denotes To date, CSCs in esophageal cancer have not been characterized.
T4 301-364 Sentence denotes To date, CSCs in esophageal cancer have not been characterized.
TextSentencer_T5 365-662 Sentence denotes In the current study, we detected significant higher levels of placental growth factor (PLGF) and matrix metalloproteinase 9 (MMP9) in the esophageal cancers with metastasis, compared to those without metastasis, in which the expression levels of PLGF and MMP9 strongly correlated with each other.
T5 365-662 Sentence denotes In the current study, we detected significant higher levels of placental growth factor (PLGF) and matrix metalloproteinase 9 (MMP9) in the esophageal cancers with metastasis, compared to those without metastasis, in which the expression levels of PLGF and MMP9 strongly correlated with each other.
TextSentencer_T6 663-763 Sentence denotes Thus, we used a human esophageal cancer cell line, TE-1, to examine the cross talk of PLGF and MMP9.
T6 663-763 Sentence denotes Thus, we used a human esophageal cancer cell line, TE-1, to examine the cross talk of PLGF and MMP9.
TextSentencer_T7 764-979 Sentence denotes We found that the levels of PLGF in TE-1 cells positively affected the levels of MMP9, while the levels of MMP9 did not affected the levels of PLGF, suggesting that PLGF may activate MMP9 in esophageal cancer cells.
T7 764-979 Sentence denotes We found that the levels of PLGF in TE-1 cells positively affected the levels of MMP9, while the levels of MMP9 did not affected the levels of PLGF, suggesting that PLGF may activate MMP9 in esophageal cancer cells.
TextSentencer_T8 980-1128 Sentence denotes Then, we separated PLGF-positive and PLGF-negative TE-1 cells that had been transfected with a GFP reporter under a PLGF promoter by flow cytometry.
T8 980-1128 Sentence denotes Then, we separated PLGF-positive and PLGF-negative TE-1 cells that had been transfected with a GFP reporter under a PLGF promoter by flow cytometry.
TextSentencer_T9 1129-1353 Sentence denotes We found that PLGF-positive cells grew significantly faster than PLGF-negative cells both in vitro and in vivo in a stereotactical implantation model, suggesting that PLGF-positive cells are likely CSCs in esophageal cancer.
T9 1129-1353 Sentence denotes We found that PLGF-positive cells grew significantly faster than PLGF-negative cells both in vitro and in vivo in a stereotactical implantation model, suggesting that PLGF-positive cells are likely CSCs in esophageal cancer.
TextSentencer_T10 1354-1529 Sentence denotes Taken together, we demonstrate that PLGF-positive cells appear to be CSCs in esophageal cancer, and they may release PLGF to promote cancer metastasis through MMP9 activation.
T10 1354-1529 Sentence denotes Taken together, we demonstrate that PLGF-positive cells appear to be CSCs in esophageal cancer, and they may release PLGF to promote cancer metastasis through MMP9 activation.