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PubMed:24996823 JSONTXT 54 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-71 Sentence denotes Galectin-3 promotes HIV-1 budding via association with Alix and Gag p6.
T1 0-71 Sentence denotes Galectin-3 promotes HIV-1 budding via association with Alix and Gag p6.
T1 0-71 Sentence denotes Galectin-3 promotes HIV-1 budding via association with Alix and Gag p6.
TextSentencer_T2 72-160 Sentence denotes Galectin-3 has been reported to regulate the functions of a number of immune cell types.
T2 72-160 Sentence denotes Galectin-3 has been reported to regulate the functions of a number of immune cell types.
T2 72-160 Sentence denotes Galectin-3 has been reported to regulate the functions of a number of immune cell types.
TextSentencer_T3 161-346 Sentence denotes We previously reported that galectin-3 is translocated to immunological synapses in T cells upon T-cell receptor engagement, where it associates with ALG-2-interacting protein X (Alix).
T3 161-346 Sentence denotes We previously reported that galectin-3 is translocated to immunological synapses in T cells upon T-cell receptor engagement, where it associates with ALG-2-interacting protein X (Alix).
T3 161-346 Sentence denotes We previously reported that galectin-3 is translocated to immunological synapses in T cells upon T-cell receptor engagement, where it associates with ALG-2-interacting protein X (Alix).
TextSentencer_T4 347-504 Sentence denotes Alix is known to coordinate with the endosomal sorting complex required for transport (ESCRT) to promote human immunodeficiency virus (HIV)-1 virion release.
T4 347-504 Sentence denotes Alix is known to coordinate with the endosomal sorting complex required for transport (ESCRT) to promote human immunodeficiency virus (HIV)-1 virion release.
T4 347-504 Sentence denotes Alix is known to coordinate with the endosomal sorting complex required for transport (ESCRT) to promote human immunodeficiency virus (HIV)-1 virion release.
TextSentencer_T5 505-573 Sentence denotes We hypothesized that galectin-3 plays a role in HIV-1 viral budding.
T5 505-573 Sentence denotes We hypothesized that galectin-3 plays a role in HIV-1 viral budding.
T5 505-573 Sentence denotes We hypothesized that galectin-3 plays a role in HIV-1 viral budding.
TextSentencer_T6 574-803 Sentence denotes Cotransfection of cells of the Jurkat T line with galectin-3 and HIV-1 plasmids resulted in increased HIV-1 budding, and suppression of galectin-3 expression by RNAi in Hut78 and primary CD4+ T cells led to reduced HIV-1 budding.
T6 574-803 Sentence denotes Cotransfection of cells of the Jurkat T line with galectin-3 and HIV-1 plasmids resulted in increased HIV-1 budding, and suppression of galectin-3 expression by RNAi in Hut78 and primary CD4+ T cells led to reduced HIV-1 budding.
T6 574-803 Sentence denotes Cotransfection of cells of the Jurkat T line with galectin-3 and HIV-1 plasmids resulted in increased HIV-1 budding, and suppression of galectin-3 expression by RNAi in Hut78 and primary CD4+ T cells led to reduced HIV-1 budding.
TextSentencer_T7 804-932 Sentence denotes We used immunofluorescence microscopy to observe the partial colocalization of galectin-3, Alix and Gag in HIV-1-infected cells.
T7 804-932 Sentence denotes We used immunofluorescence microscopy to observe the partial colocalization of galectin-3, Alix and Gag in HIV-1-infected cells.
T7 804-932 Sentence denotes We used immunofluorescence microscopy to observe the partial colocalization of galectin-3, Alix and Gag in HIV-1-infected cells.
TextSentencer_T8 933-1149 Sentence denotes Results from co-immunoprecipitation experiments indicate that galectin-3 expression promotes Alix-Gag p6 association, whereas the results of Alix knockdown suggest that galectin-3 promotes HIV-1 budding through Alix.
T8 933-1149 Sentence denotes Results from co-immunoprecipitation experiments indicate that galectin-3 expression promotes Alix-Gag p6 association, whereas the results of Alix knockdown suggest that galectin-3 promotes HIV-1 budding through Alix.
T8 933-1320 Sentence denotes Results from co-immunoprecipitation experiments indicate that galectin-3 expression promotes Alix-Gag p6 association, whereas the results of Alix knockdown suggest that galectin-3 promotes HIV-1 budding through Alix. HIV-1 particles released from galectin-3-expressing cells acquire the galectin-3 protein in an Alix-dependent manner, with proteins primarily residing inside the virions.
TextSentencer_T9 1150-1320 Sentence denotes HIV-1 particles released from galectin-3-expressing cells acquire the galectin-3 protein in an Alix-dependent manner, with proteins primarily residing inside the virions.
T9 1150-1320 Sentence denotes HIV-1 particles released from galectin-3-expressing cells acquire the galectin-3 protein in an Alix-dependent manner, with proteins primarily residing inside the virions.
TextSentencer_T10 1321-1420 Sentence denotes We also found that the galectin-3 N-terminal domain interacts with the proline-rich region of Alix.
T10 1321-1420 Sentence denotes We also found that the galectin-3 N-terminal domain interacts with the proline-rich region of Alix.
T9 1321-1551 Sentence denotes We also found that the galectin-3 N-terminal domain interacts with the proline-rich region of Alix. Collectively, these results suggest that endogenous galectin-3 facilitates HIV-1 budding by promoting the Alix-Gag p6 association.
TextSentencer_T11 1421-1551 Sentence denotes Collectively, these results suggest that endogenous galectin-3 facilitates HIV-1 budding by promoting the Alix-Gag p6 association.
T11 1421-1551 Sentence denotes Collectively, these results suggest that endogenous galectin-3 facilitates HIV-1 budding by promoting the Alix-Gag p6 association.