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PubMed:24013903 JSONTXT 68 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-86 Sentence denotes Phosphorylation and externalization of galectin-4 is controlled by Src family kinases.
T1 0-86 Sentence denotes Phosphorylation and externalization of galectin-4 is controlled by Src family kinases.
TextSentencer_T2 87-228 Sentence denotes Galectin-4 is a cytosolic protein that lacks a signal sequence but is externalized and binds to 3-O-sulfated glycoconjugates extracellularly.
T2 87-228 Sentence denotes Galectin-4 is a cytosolic protein that lacks a signal sequence but is externalized and binds to 3-O-sulfated glycoconjugates extracellularly.
TextSentencer_T3 229-333 Sentence denotes The mechanism of subcellular localization and externalization of galectin-4 has not yet been determined.
T3 229-333 Sentence denotes The mechanism of subcellular localization and externalization of galectin-4 has not yet been determined.
TextSentencer_T4 334-485 Sentence denotes A preliminary experiment using pervanadate (PV) showed that galectin-4 is tyrosine-phosphorylated in cells and suggested that Src kinases are involved.
T4 334-485 Sentence denotes A preliminary experiment using pervanadate (PV) showed that galectin-4 is tyrosine-phosphorylated in cells and suggested that Src kinases are involved.
TextSentencer_T5 486-634 Sentence denotes Cell transfection with galectin-4 and active Src plasmids showed that galectin-4 can be tyrosine phosphorylated by members of the Src kinase family.
T5 486-634 Sentence denotes Cell transfection with galectin-4 and active Src plasmids showed that galectin-4 can be tyrosine phosphorylated by members of the Src kinase family.
TextSentencer_T6 635-817 Sentence denotes The C-terminal peptide YVQI of galectin-4 was found to play an important role in its tyrosine phosphorylation, and the SH2 domains of Src and SHP2 were found to bind to this peptide.
T6 635-817 Sentence denotes The C-terminal peptide YVQI of galectin-4 was found to play an important role in its tyrosine phosphorylation, and the SH2 domains of Src and SHP2 were found to bind to this peptide.
TextSentencer_T7 818-993 Sentence denotes Immunofluorescence analysis showed that galectin-4 and phosphorylated proteins were intensely stained in the area of membrane protrusions of PV-treated or Src-activated cells.
T7 818-993 Sentence denotes Immunofluorescence analysis showed that galectin-4 and phosphorylated proteins were intensely stained in the area of membrane protrusions of PV-treated or Src-activated cells.
TextSentencer_T8 994-1192 Sentence denotes Furthermore, MUC1 derived from NUGC-4 cells was observed to bind to galectin-4, and externalization of the bound molecules from the cell to the medium increased in the hyperphosphorylated condition.
T8 994-1192 Sentence denotes Furthermore, MUC1 derived from NUGC-4 cells was observed to bind to galectin-4, and externalization of the bound molecules from the cell to the medium increased in the hyperphosphorylated condition.
TextSentencer_T9 1193-1367 Sentence denotes Study of the transfection of the mutant galectin-4 which lacks the C-terminal peptide revealed that the phosphorylation status is important for externalization of galectin-4.
T9 1193-1367 Sentence denotes Study of the transfection of the mutant galectin-4 which lacks the C-terminal peptide revealed that the phosphorylation status is important for externalization of galectin-4.
TextSentencer_T10 1368-1581 Sentence denotes These results suggest that externalization of galectin-4 can be regulated by signaling molecules and that it may function intracellularly as an adaptor protein serving to modulate the trafficking of glycoproteins.
T10 1368-1581 Sentence denotes These results suggest that externalization of galectin-4 can be regulated by signaling molecules and that it may function intracellularly as an adaptor protein serving to modulate the trafficking of glycoproteins.