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PubMed:2394747 JSONTXT 52 Projects

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Id Subject Object Predicate Lexical cue
T1 0-239 Sentence denotes Cell type specificity and activation requirements for NFAT-1 (nuclear factor of activated T-cells) transcriptional activity determined by a new method using transgenic mice to assay transcriptional activity of an individual nuclear factor.
T1 0-239 Sentence denotes Cell type specificity and activation requirements for NFAT-1 (nuclear factor of activated T-cells) transcriptional activity determined by a new method using transgenic mice to assay transcriptional activity of an individual nuclear factor.
T2 240-387 Sentence denotes Nuclear factor of activated T-cells (NFAT-1) is a transcription factor which is considered to be an important regulator in early T-cell activation.
T2 240-387 Sentence denotes Nuclear factor of activated T-cells (NFAT-1) is a transcription factor which is considered to be an important regulator in early T-cell activation.
T3 388-507 Sentence denotes We have developed a system to monitor the transcriptional activity of NFAT-1 at the single cell level in whole animals.
T3 388-507 Sentence denotes We have developed a system to monitor the transcriptional activity of NFAT-1 at the single cell level in whole animals.
T4 508-643 Sentence denotes The system is based on the use of an oligomerized NFAT-1 binding motif that directs transcription of SV40 T-antigen in transgenic mice.
T4 508-643 Sentence denotes The system is based on the use of an oligomerized NFAT-1 binding motif that directs transcription of SV40 T-antigen in transgenic mice.
T5 644-777 Sentence denotes This report represents the first demonstration that a multimerized short binding motif can function appropriately in transgenic mice.
T5 644-777 Sentence denotes This report represents the first demonstration that a multimerized short binding motif can function appropriately in transgenic mice.
T6 778-902 Sentence denotes NFAT-1 activity had previously been thought to be confined to activated T-lymphocytes upon release of intracellular calcium.
T6 778-902 Sentence denotes NFAT-1 activity had previously been thought to be confined to activated T-lymphocytes upon release of intracellular calcium.
T7 903-1011 Sentence denotes By targeting NFAT-1-dependent gene expression in transgenic mice we discovered new sites of NFAT-1 activity.
T7 903-1011 Sentence denotes By targeting NFAT-1-dependent gene expression in transgenic mice we discovered new sites of NFAT-1 activity.
T8 1012-1230 Sentence denotes Besides in T-lymphocytes NFAT-1 activity could also be induced in T-lymphocyte-depleted spleen cells and purified B-lymphocytes and requires agents that both release intracellular calcium and activate protein kinase C.
T8 1012-1230 Sentence denotes Besides in T-lymphocytes NFAT-1 activity could also be induced in T-lymphocyte-depleted spleen cells and purified B-lymphocytes and requires agents that both release intracellular calcium and activate protein kinase C.
T9 1231-1353 Sentence denotes A difference in the time course of appearance of NFAT-1 activity between T-lymphocytes and non-T-lymphocytes was revealed.
T9 1231-1353 Sentence denotes A difference in the time course of appearance of NFAT-1 activity between T-lymphocytes and non-T-lymphocytes was revealed.
T10 1354-1478 Sentence denotes Constitutive expression was observed in a small population of cells in the dermis and some mice have developed skin lesions.
T10 1354-1478 Sentence denotes Constitutive expression was observed in a small population of cells in the dermis and some mice have developed skin lesions.
T11 1479-1649 Sentence denotes Interestingly, the tissue pattern of expression of the NFAT-1 activity resembles the expression pattern described for HIV-LTR/tat transgenic mice (Vogel, J., Hinrichs, S.
T11 1479-1649 Sentence denotes Interestingly, the tissue pattern of expression of the NFAT-1 activity resembles the expression pattern described for HIV-LTR/tat transgenic mice (Vogel, J., Hinrichs, S.
T12 1650-1666 Sentence denotes H., Reynolds, R.
T12 1650-1666 Sentence denotes H., Reynolds, R.
T13 1667-1680 Sentence denotes K., Luciw, P.
T13 1667-1680 Sentence denotes K., Luciw, P.
T14 1681-1725 Sentence denotes A., and Jay, G. (1988) Nature 335, 606-611).
T14 1681-1725 Sentence denotes A., and Jay, G. (1988) Nature 335, 606-611).
T15 1726-1898 Sentence denotes This similarity in expression and the fact that NFAT-1 has been shown to bind functional sequences in HIV-LTR suggest a role for NFAT-1 in dermal activation of the HIV-LTR.
T15 1726-1898 Sentence denotes This similarity in expression and the fact that NFAT-1 has been shown to bind functional sequences in HIV-LTR suggest a role for NFAT-1 in dermal activation of the HIV-LTR.