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PubMed:23708401 JSONTXT 66 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-84 Sentence denotes Metabolic glycoengineering of mesenchymal stromal cells with N-propanoylmannosamine.
T1 0-84 Sentence denotes Metabolic glycoengineering of mesenchymal stromal cells with N-propanoylmannosamine.
T1 0-84 Sentence denotes Metabolic glycoengineering of mesenchymal stromal cells with N-propanoylmannosamine.
TextSentencer_T2 85-214 Sentence denotes There is an increasing interest in the modification of cell surface glycosylation to improve the properties of therapeutic cells.
T2 85-214 Sentence denotes There is an increasing interest in the modification of cell surface glycosylation to improve the properties of therapeutic cells.
T2 85-214 Sentence denotes There is an increasing interest in the modification of cell surface glycosylation to improve the properties of therapeutic cells.
TextSentencer_T3 215-306 Sentence denotes For example, glycosylation affects the biodistribution of mesenchymal stromal cells (MSCs).
T3 215-306 Sentence denotes For example, glycosylation affects the biodistribution of mesenchymal stromal cells (MSCs).
T3 215-306 Sentence denotes For example, glycosylation affects the biodistribution of mesenchymal stromal cells (MSCs).
TextSentencer_T4 307-381 Sentence denotes Metabolic glycoengineering is an efficient way to modify the cell surface.
T4 307-381 Sentence denotes Metabolic glycoengineering is an efficient way to modify the cell surface.
T4 307-381 Sentence denotes Metabolic glycoengineering is an efficient way to modify the cell surface.
TextSentencer_T5 382-555 Sentence denotes The mammalian biosynthetic machinery tolerates the unnatural sialic acid precursor, N-propanoylmannosamine (ManNProp), and incorporates it into cell surface glycoconjugates.
T5 382-555 Sentence denotes The mammalian biosynthetic machinery tolerates the unnatural sialic acid precursor, N-propanoylmannosamine (ManNProp), and incorporates it into cell surface glycoconjugates.
T5 382-555 Sentence denotes The mammalian biosynthetic machinery tolerates the unnatural sialic acid precursor, N-propanoylmannosamine (ManNProp), and incorporates it into cell surface glycoconjugates.
TextSentencer_T6 556-799 Sentence denotes We show here by mass spectrometric analysis of cell surface N-glycans that about half of N-acetylneuraminic acid was replaced by N-propanoylneuraminic acid in the N-glycans of human umbilical cord blood-derived MSCs supplemented with ManNProp.
T6 556-799 Sentence denotes We show here by mass spectrometric analysis of cell surface N-glycans that about half of N-acetylneuraminic acid was replaced by N-propanoylneuraminic acid in the N-glycans of human umbilical cord blood-derived MSCs supplemented with ManNProp.
T6 556-799 Sentence denotes We show here by mass spectrometric analysis of cell surface N-glycans that about half of N-acetylneuraminic acid was replaced by N-propanoylneuraminic acid in the N-glycans of human umbilical cord blood-derived MSCs supplemented with ManNProp.
TextSentencer_T7 800-846 Sentence denotes In addition, the N-glycan profile was altered.
T7 800-846 Sentence denotes In addition, the N-glycan profile was altered.
T7 800-846 Sentence denotes In addition, the N-glycan profile was altered.
TextSentencer_T8 847-941 Sentence denotes ManNProp-supplemented cells had more multiply fucosylated N-glycan species than control cells.
T8 847-941 Sentence denotes ManNProp-supplemented cells had more multiply fucosylated N-glycan species than control cells.
T8 847-941 Sentence denotes ManNProp-supplemented cells had more multiply fucosylated N-glycan species than control cells.
TextSentencer_T9 942-1087 Sentence denotes The fucosylated epitopes were shown in tandem mass spectrometric analysis to be Lewis x or blood group H epitopes, but not sialyl Lewis x (sLex).
T9 942-1087 Sentence denotes The fucosylated epitopes were shown in tandem mass spectrometric analysis to be Lewis x or blood group H epitopes, but not sialyl Lewis x (sLex).
T9 942-1087 Sentence denotes The fucosylated epitopes were shown in tandem mass spectrometric analysis to be Lewis x or blood group H epitopes, but not sialyl Lewis x (sLex).
TextSentencer_T10 1088-1212 Sentence denotes The amounts of tri- and tetra-antennary and polylactosamine-containing N-glycans also increased in ManNProp supplementation.
T10 1088-1212 Sentence denotes The amounts of tri- and tetra-antennary and polylactosamine-containing N-glycans also increased in ManNProp supplementation.
T10 1088-1212 Sentence denotes The amounts of tri- and tetra-antennary and polylactosamine-containing N-glycans also increased in ManNProp supplementation.
TextSentencer_T11 1213-1376 Sentence denotes In accordance with previous studies of other cell types, increased expression of the sLex epitope in ManNProp-supplemented MSCs was demonstrated by flow cytometry.
T11 1213-1376 Sentence denotes In accordance with previous studies of other cell types, increased expression of the sLex epitope in ManNProp-supplemented MSCs was demonstrated by flow cytometry.
T11 1213-1376 Sentence denotes In accordance with previous studies of other cell types, increased expression of the sLex epitope in ManNProp-supplemented MSCs was demonstrated by flow cytometry.
TextSentencer_T12 1377-1599 Sentence denotes In light of the N-glycan analysis, the sLex epitope in these cells is likely to be carried by O-glycans or glycolipids. sLex has been shown to target MSCs to bone marrow, which may be desirable in therapeutic applications.
T12 1377-1599 Sentence denotes In light of the N-glycan analysis, the sLex epitope in these cells is likely to be carried by O-glycans or glycolipids. sLex has been shown to target MSCs to bone marrow, which may be desirable in therapeutic applications.
T12 1377-1599 Sentence denotes In light of the N-glycan analysis, the sLex epitope in these cells is likely to be carried by O-glycans or glycolipids. sLex has been shown to target MSCs to bone marrow, which may be desirable in therapeutic applications.
TextSentencer_T13 1600-1843 Sentence denotes The present results represent the first structural analysis of an N-glycome of ManNProp-supplemented cells and demonstrate the feasibility of modifying cell surface glycosylation of therapeutic cells by this type of metabolic glycoengineering.
T13 1600-1843 Sentence denotes The present results represent the first structural analysis of an N-glycome of ManNProp-supplemented cells and demonstrate the feasibility of modifying cell surface glycosylation of therapeutic cells by this type of metabolic glycoengineering.
T13 1600-1843 Sentence denotes The present results represent the first structural analysis of an N-glycome of ManNProp-supplemented cells and demonstrate the feasibility of modifying cell surface glycosylation of therapeutic cells by this type of metabolic glycoengineering.