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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-98 Sentence denotes Outcomes of a bladder cancer screening program using home hematuria testing and molecular markers.
T1 0-98 Sentence denotes Outcomes of a bladder cancer screening program using home hematuria testing and molecular markers.
TextSentencer_T2 99-110 Sentence denotes BACKGROUND:
T2 99-110 Sentence denotes BACKGROUND:
TextSentencer_T3 111-324 Sentence denotes We previously reported the preliminary findings from a feasibility study of bladder cancer (BCa) screening with urinary molecular markers (Bladder Cancer Urine Marker Project [BLU-P]) that has now been terminated.
T3 111-324 Sentence denotes We previously reported the preliminary findings from a feasibility study of bladder cancer (BCa) screening with urinary molecular markers (Bladder Cancer Urine Marker Project [BLU-P]) that has now been terminated.
TextSentencer_T4 325-335 Sentence denotes OBJECTIVE:
T4 325-335 Sentence denotes OBJECTIVE:
TextSentencer_T5 336-442 Sentence denotes To report the final results from BLU-P to determine whether mass screening for BCa is feasible and useful.
T5 336-442 Sentence denotes To report the final results from BLU-P to determine whether mass screening for BCa is feasible and useful.
TextSentencer_T6 443-563 Sentence denotes DESIGN, SETTING, AND PARTICIPANTS: BLU-P was a Dutch population-based study initiated in 2008 to evaluate BCa screening.
T6 443-563 Sentence denotes DESIGN, SETTING, AND PARTICIPANTS: BLU-P was a Dutch population-based study initiated in 2008 to evaluate BCa screening.
TextSentencer_T7 564-718 Sentence denotes A total of 6500 men were invited to participate in the study, 1984 (30.5%) agreed, and 1747 (88.1%) men completed the protocol and were followed for 2 yr.
T7 564-718 Sentence denotes A total of 6500 men were invited to participate in the study, 1984 (30.5%) agreed, and 1747 (88.1%) men completed the protocol and were followed for 2 yr.
TextSentencer_T8 719-732 Sentence denotes INTERVENTION:
T8 719-732 Sentence denotes INTERVENTION:
TextSentencer_T9 733-1035 Sentence denotes The screening protocol included home hematuria testing followed by molecular markers-nuclear matrix protein 22 (NMP22), microsatellite analysis (MA), fibroblast growth factor receptor 3 (FGFR3) mutation snapshot assay, and a custom methylation-specific (MLPA) test-to determine the need for cystoscopy.
T9 733-1035 Sentence denotes The screening protocol included home hematuria testing followed by molecular markers-nuclear matrix protein 22 (NMP22), microsatellite analysis (MA), fibroblast growth factor receptor 3 (FGFR3) mutation snapshot assay, and a custom methylation-specific (MLPA) test-to determine the need for cystoscopy.
TextSentencer_T10 1036-1082 Sentence denotes OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS:
T10 1036-1082 Sentence denotes OUTCOME MEASUREMENTS AND STATISTICAL ANALYSIS:
TextSentencer_T11 1083-1239 Sentence denotes Outcomes included the number of cystoscopies and the cancer detection rate within and outside the protocol, as determined by linkage to national registries.
T11 1083-1239 Sentence denotes Outcomes included the number of cystoscopies and the cancer detection rate within and outside the protocol, as determined by linkage to national registries.
TextSentencer_T12 1240-1264 Sentence denotes RESULTS AND LIMITATIONS:
T12 1240-1264 Sentence denotes RESULTS AND LIMITATIONS:
TextSentencer_T13 1265-1352 Sentence denotes Overall, 409 men (23.4%) tested positive for hematuria and underwent molecular testing.
T13 1265-1352 Sentence denotes Overall, 409 men (23.4%) tested positive for hematuria and underwent molecular testing.
TextSentencer_T14 1353-1492 Sentence denotes Current smokers (n=295 [17%]) and past smokers (n=998 [58%]) were significantly more likely to test positive for hematuria than nonsmokers.
T14 1353-1492 Sentence denotes Current smokers (n=295 [17%]) and past smokers (n=998 [58%]) were significantly more likely to test positive for hematuria than nonsmokers.
TextSentencer_T15 1493-1592 Sentence denotes Seventy-one of 75 men (94.6%) with positive molecular markers underwent the recommended cystoscopy.
T15 1493-1592 Sentence denotes Seventy-one of 75 men (94.6%) with positive molecular markers underwent the recommended cystoscopy.
TextSentencer_T16 1593-1751 Sentence denotes Four BCas and one kidney tumor were detected through this sequential protocol, whereas one BCa and one kidney tumor were missed through the screening program.
T16 1593-1751 Sentence denotes Four BCas and one kidney tumor were detected through this sequential protocol, whereas one BCa and one kidney tumor were missed through the screening program.
TextSentencer_T17 1752-1812 Sentence denotes Limitations include the possibility of healthy subject bias.
T17 1752-1812 Sentence denotes Limitations include the possibility of healthy subject bias.
TextSentencer_T18 1813-1825 Sentence denotes CONCLUSIONS:
T18 1813-1825 Sentence denotes CONCLUSIONS:
TextSentencer_T19 1826-2032 Sentence denotes For BCa screening, use of a sequential protocol with home hematuria testing followed by molecular markers substantially reduced the number of cystoscopy recommendations compared with dipstick testing alone.
T19 1826-2032 Sentence denotes For BCa screening, use of a sequential protocol with home hematuria testing followed by molecular markers substantially reduced the number of cystoscopy recommendations compared with dipstick testing alone.
TextSentencer_T20 2033-2152 Sentence denotes A sequential screening approach may help minimize unnecessary invasive follow-up testing, with very few missed cancers.
T20 2033-2152 Sentence denotes A sequential screening approach may help minimize unnecessary invasive follow-up testing, with very few missed cancers.
TextSentencer_T21 2153-2282 Sentence denotes Nevertheless, this mass screening program had a very low diagnostic yield in an unselected asymptomatic European male population.
T21 2153-2282 Sentence denotes Nevertheless, this mass screening program had a very low diagnostic yield in an unselected asymptomatic European male population.