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Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-90 Sentence denotes Octamerization is essential for enzymatic function of human UDP-glucose pyrophosphorylase.
T1 0-90 Sentence denotes Octamerization is essential for enzymatic function of human UDP-glucose pyrophosphorylase.
T1 0-90 Sentence denotes Octamerization is essential for enzymatic function of human UDP-glucose pyrophosphorylase.
TextSentencer_T2 91-390 Sentence denotes Uridine diphosphate-glucose pyrophosphorylase (UGP) occupies a central position in carbohydrate metabolism in all kingdoms of life, since its product uridine diphosphate-glucose (UDP-glucose) is essential in a number of anabolic and catabolic pathways and is a precursor for other sugar nucleotides.
T2 91-390 Sentence denotes Uridine diphosphate-glucose pyrophosphorylase (UGP) occupies a central position in carbohydrate metabolism in all kingdoms of life, since its product uridine diphosphate-glucose (UDP-glucose) is essential in a number of anabolic and catabolic pathways and is a precursor for other sugar nucleotides.
T2 91-390 Sentence denotes Uridine diphosphate-glucose pyrophosphorylase (UGP) occupies a central position in carbohydrate metabolism in all kingdoms of life, since its product uridine diphosphate-glucose (UDP-glucose) is essential in a number of anabolic and catabolic pathways and is a precursor for other sugar nucleotides.
TextSentencer_T3 391-520 Sentence denotes Its significance as a virulence factor in protists and bacteria has given momentum to the search for species-specific inhibitors.
T3 391-520 Sentence denotes Its significance as a virulence factor in protists and bacteria has given momentum to the search for species-specific inhibitors.
T3 391-520 Sentence denotes Its significance as a virulence factor in protists and bacteria has given momentum to the search for species-specific inhibitors.
TextSentencer_T4 521-623 Sentence denotes These attempts are, however, hampered by high structural conservation of the active site architecture.
T4 521-623 Sentence denotes These attempts are, however, hampered by high structural conservation of the active site architecture.
T4 521-623 Sentence denotes These attempts are, however, hampered by high structural conservation of the active site architecture.
TextSentencer_T5 624-710 Sentence denotes A feature that discriminates UGPs of different species is the quaternary organization.
T5 624-710 Sentence denotes A feature that discriminates UGPs of different species is the quaternary organization.
T5 624-710 Sentence denotes A feature that discriminates UGPs of different species is the quaternary organization.
TextSentencer_T6 711-886 Sentence denotes While UGPs in protists are monomers, di- and tetrameric forms exist in bacteria, and crystal structures obtained for the enzyme from yeast and human identified octameric UGPs.
T6 711-886 Sentence denotes While UGPs in protists are monomers, di- and tetrameric forms exist in bacteria, and crystal structures obtained for the enzyme from yeast and human identified octameric UGPs.
T6 711-886 Sentence denotes While UGPs in protists are monomers, di- and tetrameric forms exist in bacteria, and crystal structures obtained for the enzyme from yeast and human identified octameric UGPs.
TextSentencer_T7 887-988 Sentence denotes These octamers are formed by contacts between highly conserved amino acids in the C-terminal β-helix.
T7 887-988 Sentence denotes These octamers are formed by contacts between highly conserved amino acids in the C-terminal β-helix.
T7 887-988 Sentence denotes These octamers are formed by contacts between highly conserved amino acids in the C-terminal β-helix.
TextSentencer_T8 989-1101 Sentence denotes Still under debate is the question whether octamerization is required for the functionality of the human enzyme.
T8 989-1101 Sentence denotes Still under debate is the question whether octamerization is required for the functionality of the human enzyme.
T8 989-1101 Sentence denotes Still under debate is the question whether octamerization is required for the functionality of the human enzyme.
TextSentencer_T9 1102-1293 Sentence denotes Here, we used single amino acid replacements in the C-terminal β-helix to interrogate the impact of highly conserved residues on octamer formation and functional activity of human UGP (hUGP).
T9 1102-1293 Sentence denotes Here, we used single amino acid replacements in the C-terminal β-helix to interrogate the impact of highly conserved residues on octamer formation and functional activity of human UGP (hUGP).
T9 1102-1293 Sentence denotes Here, we used single amino acid replacements in the C-terminal β-helix to interrogate the impact of highly conserved residues on octamer formation and functional activity of human UGP (hUGP).
TextSentencer_T10 1294-1396 Sentence denotes Replacements were guided by the sequence of Arabidopsis thaliana UGP, known to be active as a monomer.
T10 1294-1396 Sentence denotes Replacements were guided by the sequence of Arabidopsis thaliana UGP, known to be active as a monomer.
T10 1294-1396 Sentence denotes Replacements were guided by the sequence of Arabidopsis thaliana UGP, known to be active as a monomer.
TextSentencer_T11 1397-1562 Sentence denotes Correlating the data obtained in blue native PAGE, size exclusion chromatography and enzymatic activity testing, we prove that the octamer is the active enzyme form.
T11 1397-1562 Sentence denotes Correlating the data obtained in blue native PAGE, size exclusion chromatography and enzymatic activity testing, we prove that the octamer is the active enzyme form.
T11 1397-1562 Sentence denotes Correlating the data obtained in blue native PAGE, size exclusion chromatography and enzymatic activity testing, we prove that the octamer is the active enzyme form.
TextSentencer_T12 1563-1826 Sentence denotes This new insight into structure-function relationships in hUGP does not only improve the understanding of the catalysis of this important enzyme, but in addition broadens the basis for studies aimed at designing drugs that selectively inhibit UGPs from pathogens.
T12 1563-1826 Sentence denotes This new insight into structure-function relationships in hUGP does not only improve the understanding of the catalysis of this important enzyme, but in addition broadens the basis for studies aimed at designing drugs that selectively inhibit UGPs from pathogens.
T12 1563-1826 Sentence denotes This new insight into structure-function relationships in hUGP does not only improve the understanding of the catalysis of this important enzyme, but in addition broadens the basis for studies aimed at designing drugs that selectively inhibit UGPs from pathogens.