Id |
Subject |
Object |
Predicate |
Lexical cue |
TextSentencer_T1 |
0-95 |
Sentence |
denotes |
Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss. |
T1 |
0-95 |
Sentence |
denotes |
Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss. |
T1 |
0-95 |
Sentence |
denotes |
Galectin-1 confers immune privilege to human trophoblast: implications in recurrent fetal loss. |
TextSentencer_T2 |
96-223 |
Sentence |
denotes |
Mechanisms accounting for the protection of the fetal semi-allograft from maternal immune cells remain incompletely understood. |
T2 |
96-223 |
Sentence |
denotes |
Mechanisms accounting for the protection of the fetal semi-allograft from maternal immune cells remain incompletely understood. |
T2 |
96-223 |
Sentence |
denotes |
Mechanisms accounting for the protection of the fetal semi-allograft from maternal immune cells remain incompletely understood. |
TextSentencer_T3 |
224-415 |
Sentence |
denotes |
In previous studies, we showed that galectin-1 (Gal1), an immunoregulatory glycan-binding protein, hierarchically triggers a cascade of tolerogenic events at the mouse fetomaternal interface. |
T3 |
224-415 |
Sentence |
denotes |
In previous studies, we showed that galectin-1 (Gal1), an immunoregulatory glycan-binding protein, hierarchically triggers a cascade of tolerogenic events at the mouse fetomaternal interface. |
T3 |
224-415 |
Sentence |
denotes |
In previous studies, we showed that galectin-1 (Gal1), an immunoregulatory glycan-binding protein, hierarchically triggers a cascade of tolerogenic events at the mouse fetomaternal interface. |
TextSentencer_T4 |
416-552 |
Sentence |
denotes |
Here, we show that Gal1 confers immune privilege to human trophoblast cells through the modulation of a number of regulatory mechanisms. |
T4 |
416-552 |
Sentence |
denotes |
Here, we show that Gal1 confers immune privilege to human trophoblast cells through the modulation of a number of regulatory mechanisms. |
T4 |
416-552 |
Sentence |
denotes |
Here, we show that Gal1 confers immune privilege to human trophoblast cells through the modulation of a number of regulatory mechanisms. |
TextSentencer_T5 |
553-704 |
Sentence |
denotes |
Gal1 was mainly expressed in invasive extravillous trophoblast cells of human first trimester and term placenta in direct contact with maternal tissue. |
T5 |
553-704 |
Sentence |
denotes |
Gal1 was mainly expressed in invasive extravillous trophoblast cells of human first trimester and term placenta in direct contact with maternal tissue. |
T5 |
553-704 |
Sentence |
denotes |
Gal1 was mainly expressed in invasive extravillous trophoblast cells of human first trimester and term placenta in direct contact with maternal tissue. |
TextSentencer_T6 |
705-1025 |
Sentence |
denotes |
Expression of Gal1 by the human trophoblast cell line JEG-3 was primarily controlled by progesterone and pro-inflammatory cytokines and impaired T-cell responses by limiting T cell viability, suppressing the secretion of Th1-type cytokines and favoring the expansion of CD4(+)CD25(+)FoxP3(+) regulatory T (T(reg)) cells. |
T6 |
705-1025 |
Sentence |
denotes |
Expression of Gal1 by the human trophoblast cell line JEG-3 was primarily controlled by progesterone and pro-inflammatory cytokines and impaired T-cell responses by limiting T cell viability, suppressing the secretion of Th1-type cytokines and favoring the expansion of CD4(+)CD25(+)FoxP3(+) regulatory T (T(reg)) cells. |
T6 |
705-1025 |
Sentence |
denotes |
Expression of Gal1 by the human trophoblast cell line JEG-3 was primarily controlled by progesterone and pro-inflammatory cytokines and impaired T-cell responses by limiting T cell viability, suppressing the secretion of Th1-type cytokines and favoring the expansion of CD4(+)CD25(+)FoxP3(+) regulatory T (T(reg)) cells. |
TextSentencer_T7 |
1026-1233 |
Sentence |
denotes |
Targeted inhibition of Gal1 expression through antibody (Ab)-mediated blockade, addition of the specific disaccharide lactose or retroviral-mediated siRNA strategies prevented these immunoregulatory effects. |
T7 |
1026-1233 |
Sentence |
denotes |
Targeted inhibition of Gal1 expression through antibody (Ab)-mediated blockade, addition of the specific disaccharide lactose or retroviral-mediated siRNA strategies prevented these immunoregulatory effects. |
T7 |
1026-1233 |
Sentence |
denotes |
Targeted inhibition of Gal1 expression through antibody (Ab)-mediated blockade, addition of the specific disaccharide lactose or retroviral-mediated siRNA strategies prevented these immunoregulatory effects. |
TextSentencer_T8 |
1234-1470 |
Sentence |
denotes |
Consistent with a homeostatic role of endogenous Gal1, patients with recurrent pregnancy loss showed considerably lower levels of circulating Gal1 and had higher frequency of anti-Gal1 auto-Abs in their sera compared with fertile women. |
T8 |
1234-1470 |
Sentence |
denotes |
Consistent with a homeostatic role of endogenous Gal1, patients with recurrent pregnancy loss showed considerably lower levels of circulating Gal1 and had higher frequency of anti-Gal1 auto-Abs in their sera compared with fertile women. |
T8 |
1234-1470 |
Sentence |
denotes |
Consistent with a homeostatic role of endogenous Gal1, patients with recurrent pregnancy loss showed considerably lower levels of circulating Gal1 and had higher frequency of anti-Gal1 auto-Abs in their sera compared with fertile women. |
TextSentencer_T9 |
1471-1641 |
Sentence |
denotes |
Thus, endogenous Gal1 confers immune privilege to human trophoblast cells by triggering a broad tolerogenic program with potential implications in threatened pregnancies. |
T9 |
1471-1641 |
Sentence |
denotes |
Thus, endogenous Gal1 confers immune privilege to human trophoblast cells by triggering a broad tolerogenic program with potential implications in threatened pregnancies. |
T9 |
1471-1641 |
Sentence |
denotes |
Thus, endogenous Gal1 confers immune privilege to human trophoblast cells by triggering a broad tolerogenic program with potential implications in threatened pregnancies. |