Id |
Subject |
Object |
Predicate |
Lexical cue |
TextSentencer_T1 |
0-126 |
Sentence |
denotes |
Development of an AlphaLISA assay to quantify serum core-fucosylated E-cadherin as a metastatic lung adenocarcinoma biomarker. |
T1 |
0-126 |
Sentence |
denotes |
Development of an AlphaLISA assay to quantify serum core-fucosylated E-cadherin as a metastatic lung adenocarcinoma biomarker. |
TextSentencer_T2 |
127-198 |
Sentence |
denotes |
Lung cancer is the leading cause of cancer-associated deaths worldwide. |
T2 |
127-198 |
Sentence |
denotes |
Lung cancer is the leading cause of cancer-associated deaths worldwide. |
TextSentencer_T3 |
199-325 |
Sentence |
denotes |
Non-small cell lung cancer is a heterogeneous condition with variability in prognosis and in individual response to treatment. |
T3 |
199-325 |
Sentence |
denotes |
Non-small cell lung cancer is a heterogeneous condition with variability in prognosis and in individual response to treatment. |
TextSentencer_T4 |
326-449 |
Sentence |
denotes |
Thus, the identification of patients with a high risk of metastasis or relapse after surgery would allow better management. |
T4 |
326-449 |
Sentence |
denotes |
Thus, the identification of patients with a high risk of metastasis or relapse after surgery would allow better management. |
TextSentencer_T5 |
450-597 |
Sentence |
denotes |
There is increasing evidence that glycosylation plays a significant role in biological processes including oncogenic transformation and metastasis. |
T5 |
450-597 |
Sentence |
denotes |
There is increasing evidence that glycosylation plays a significant role in biological processes including oncogenic transformation and metastasis. |
TextSentencer_T6 |
598-702 |
Sentence |
denotes |
We set up a platform to screen and identify serum glycoproteins as metastasis biomarkers of lung cancer. |
T6 |
598-702 |
Sentence |
denotes |
We set up a platform to screen and identify serum glycoproteins as metastasis biomarkers of lung cancer. |
TextSentencer_T7 |
703-825 |
Sentence |
denotes |
Concanavalin A affinity chromatography was used to enrich glycoproteins from pooled serum of lung adenocarcinoma patients. |
T7 |
703-825 |
Sentence |
denotes |
Concanavalin A affinity chromatography was used to enrich glycoproteins from pooled serum of lung adenocarcinoma patients. |
TextSentencer_T8 |
826-947 |
Sentence |
denotes |
The captured glycoproteins were separated with 2-D DIGE combined with nano-LC-MS/MS and identified by database searching. |
T8 |
826-947 |
Sentence |
denotes |
The captured glycoproteins were separated with 2-D DIGE combined with nano-LC-MS/MS and identified by database searching. |
TextSentencer_T9 |
948-1094 |
Sentence |
denotes |
Some differentially expressed cancer-related glycoproteins, such as α-1-antitrypsin, complement C3c, haptoglobin, and E-cadherin, were identified. |
T9 |
948-1094 |
Sentence |
denotes |
Some differentially expressed cancer-related glycoproteins, such as α-1-antitrypsin, complement C3c, haptoglobin, and E-cadherin, were identified. |
TextSentencer_T10 |
1095-1288 |
Sentence |
denotes |
These glycoproteins were evaluated by Western blotting and Aleuria aurantia lectin staining and several, including E-cadherin, showed increased core-fucosylation during lung cancer progression. |
T10 |
1095-1288 |
Sentence |
denotes |
These glycoproteins were evaluated by Western blotting and Aleuria aurantia lectin staining and several, including E-cadherin, showed increased core-fucosylation during lung cancer progression. |
TextSentencer_T11 |
1289-1384 |
Sentence |
denotes |
We then measured the fucosylation index (FI) of E-cadherin in 154 lung adenocarcinoma patients. |
T11 |
1289-1384 |
Sentence |
denotes |
We then measured the fucosylation index (FI) of E-cadherin in 154 lung adenocarcinoma patients. |
TextSentencer_T12 |
1385-1492 |
Sentence |
denotes |
In addition, a homogeneous proximity-based AlphaLISA assay to measure the FI of E-cadherin was established. |
T12 |
1385-1492 |
Sentence |
denotes |
In addition, a homogeneous proximity-based AlphaLISA assay to measure the FI of E-cadherin was established. |
TextSentencer_T13 |
1493-1620 |
Sentence |
denotes |
The present study indicates that the FI of E-cadherin could be a potential prognostic marker of metastatic lung adenocarcinoma. |
T13 |
1493-1620 |
Sentence |
denotes |
The present study indicates that the FI of E-cadherin could be a potential prognostic marker of metastatic lung adenocarcinoma. |