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PubMed:22492204 JSONTXT 52 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-110 Sentence denotes Hypersialylated type-I lactosamine-containing N-glycans found in Artiodactyla sera are potential xenoantigens.
T1 0-110 Sentence denotes Hypersialylated type-I lactosamine-containing N-glycans found in Artiodactyla sera are potential xenoantigens.
T1 0-110 Sentence denotes Hypersialylated type-I lactosamine-containing N-glycans found in Artiodactyla sera are potential xenoantigens.
TextSentencer_T2 111-201 Sentence denotes There is increasing interest in biologics, i.e. human-originated biological pharmaceutics.
T2 111-201 Sentence denotes There is increasing interest in biologics, i.e. human-originated biological pharmaceutics.
T2 111-201 Sentence denotes There is increasing interest in biologics, i.e. human-originated biological pharmaceutics.
TextSentencer_T3 202-482 Sentence denotes Most of the protein drugs developed so far, such as immunoglobulins and erythropoietin, are secreted glycoproteins; as a result, any non-human-type glycans, such as αGal and NeuGc, derived from animal cells and sera must be removed to circumvent undesirable immunogenic reactions.
T3 202-482 Sentence denotes Most of the protein drugs developed so far, such as immunoglobulins and erythropoietin, are secreted glycoproteins; as a result, any non-human-type glycans, such as αGal and NeuGc, derived from animal cells and sera must be removed to circumvent undesirable immunogenic reactions.
T3 202-482 Sentence denotes Most of the protein drugs developed so far, such as immunoglobulins and erythropoietin, are secreted glycoproteins; as a result, any non-human-type glycans, such as αGal and NeuGc, derived from animal cells and sera must be removed to circumvent undesirable immunogenic reactions.
TextSentencer_T4 483-594 Sentence denotes In this study, we made an extensive search for potential xenoantigenic glycans among a panel of mammalian sera.
T4 483-594 Sentence denotes In this study, we made an extensive search for potential xenoantigenic glycans among a panel of mammalian sera.
T4 483-594 Sentence denotes In this study, we made an extensive search for potential xenoantigenic glycans among a panel of mammalian sera.
TextSentencer_T5 595-886 Sentence denotes As a result, sera belonging to the order Artiodactyla, i.e. bovine, lamb and goat sera, were found to contain substantial amounts of hypersialylated biantennary glycans closely associated with a type-I lactosamine structure containing a unique tetrasaccharide, Siaα2-3Galβ1-3(Siaα2-6)GlcNAc.
T5 595-886 Sentence denotes As a result, sera belonging to the order Artiodactyla, i.e. bovine, lamb and goat sera, were found to contain substantial amounts of hypersialylated biantennary glycans closely associated with a type-I lactosamine structure containing a unique tetrasaccharide, Siaα2-3Galβ1-3(Siaα2-6)GlcNAc.
T5 595-886 Sentence denotes As a result, sera belonging to the order Artiodactyla, i.e. bovine, lamb and goat sera, were found to contain substantial amounts of hypersialylated biantennary glycans closely associated with a type-I lactosamine structure containing a unique tetrasaccharide, Siaα2-3Galβ1-3(Siaα2-6)GlcNAc.
TextSentencer_T6 887-1048 Sentence denotes In all three Artiodactyla sera, the most abundant structure was Siaα2-3Galβ1-3(Siaα2-6)GlcNAcβ1-2Manα1-3[Siaα2-6Galβ1-4GlcNAcβ1-2Manα1-6]Manβ1-4GlcNAcβ1-4GlcNAc.
T6 887-1048 Sentence denotes In all three Artiodactyla sera, the most abundant structure was Siaα2-3Galβ1-3(Siaα2-6)GlcNAcβ1-2Manα1-3[Siaα2-6Galβ1-4GlcNAcβ1-2Manα1-6]Manβ1-4GlcNAcβ1-4GlcNAc.
T6 887-1048 Sentence denotes In all three Artiodactyla sera, the most abundant structure was Siaα2-3Galβ1-3(Siaα2-6)GlcNAcβ1-2Manα1-3[Siaα2-6Galβ1-4GlcNAcβ1-2Manα1-6]Manβ1-4GlcNAcβ1-4GlcNAc.
TextSentencer_T7 1049-1244 Sentence denotes A dually hypersialylated biantennary structure, Siaα2-3Galβ1-3(Siaα2-6)GlcNAcβ1-2Manα1-3[Siaα2-3Galβ1-3(Siaα2-6)GlcNAcβ1-2Manα1-6]Manβ1-4GlcNAcβ1-4GlcNAc, was also abundant (10%) in bovine serum.
T7 1049-1244 Sentence denotes A dually hypersialylated biantennary structure, Siaα2-3Galβ1-3(Siaα2-6)GlcNAcβ1-2Manα1-3[Siaα2-3Galβ1-3(Siaα2-6)GlcNAcβ1-2Manα1-6]Manβ1-4GlcNAcβ1-4GlcNAc, was also abundant (10%) in bovine serum.
T7 1049-1244 Sentence denotes A dually hypersialylated biantennary structure, Siaα2-3Galβ1-3(Siaα2-6)GlcNAcβ1-2Manα1-3[Siaα2-3Galβ1-3(Siaα2-6)GlcNAcβ1-2Manα1-6]Manβ1-4GlcNAcβ1-4GlcNAc, was also abundant (10%) in bovine serum.
TextSentencer_T8 1245-1377 Sentence denotes The amount of hypersialylated glycans among total sialylated glycans was 46, 26 and 23% in bovine, lamb and goat sera, respectively.
T8 1245-1377 Sentence denotes The amount of hypersialylated glycans among total sialylated glycans was 46, 26 and 23% in bovine, lamb and goat sera, respectively.
T8 1245-1377 Sentence denotes The amount of hypersialylated glycans among total sialylated glycans was 46, 26 and 23% in bovine, lamb and goat sera, respectively.
TextSentencer_T9 1378-1480 Sentence denotes On the other hand, such structures could not be detected in the sera of other animals including human.
T9 1378-1480 Sentence denotes On the other hand, such structures could not be detected in the sera of other animals including human.
T9 1378-1480 Sentence denotes On the other hand, such structures could not be detected in the sera of other animals including human.
TextSentencer_T10 1481-1786 Sentence denotes The biological functions and the immunogenicity of the hypersialylated glycans in these animals remain to be elucidated; however, it is worth noting that glycoproteins biosynthesized from Artiodactyla cells and those contaminated with bovine serum might enhance undesirable antigenicity in human patients.
T10 1481-1786 Sentence denotes The biological functions and the immunogenicity of the hypersialylated glycans in these animals remain to be elucidated; however, it is worth noting that glycoproteins biosynthesized from Artiodactyla cells and those contaminated with bovine serum might enhance undesirable antigenicity in human patients.
T10 1481-1786 Sentence denotes The biological functions and the immunogenicity of the hypersialylated glycans in these animals remain to be elucidated; however, it is worth noting that glycoproteins biosynthesized from Artiodactyla cells and those contaminated with bovine serum might enhance undesirable antigenicity in human patients.