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PubMed:22134358 JSONTXT 42 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-189 Sentence denotes Potential drug targets on insomnia and intervention effects of Jujuboside A through metabolic pathway analysis as revealed by UPLC/ESI-SYNAPT-HDMS coupled with pattern recognition approach.
T1 0-189 Sentence denotes Potential drug targets on insomnia and intervention effects of Jujuboside A through metabolic pathway analysis as revealed by UPLC/ESI-SYNAPT-HDMS coupled with pattern recognition approach.
TextSentencer_T2 190-322 Sentence denotes Potential metabolites from the metabolic pathways could be therapeutic targets and useful for the discovery of broad spectrum drugs.
T2 190-322 Sentence denotes Potential metabolites from the metabolic pathways could be therapeutic targets and useful for the discovery of broad spectrum drugs.
TextSentencer_T3 323-545 Sentence denotes UPLC/ESI-SYNAPT-HDMS coupled with pattern recognition methods including PCA, PLS-DA, OPLS-DA and Heatmap were integrated to examine the global metabolic signature of insomnia and intervention effects of Jujuboside A (JuA).
T3 323-545 Sentence denotes UPLC/ESI-SYNAPT-HDMS coupled with pattern recognition methods including PCA, PLS-DA, OPLS-DA and Heatmap were integrated to examine the global metabolic signature of insomnia and intervention effects of Jujuboside A (JuA).
TextSentencer_T4 546-646 Sentence denotes Six unique pathways of the insomnia were identified using Ingenuity Pathway Analysis (IPA) software.
T4 546-646 Sentence denotes Six unique pathways of the insomnia were identified using Ingenuity Pathway Analysis (IPA) software.
TextSentencer_T5 647-783 Sentence denotes The VIP-value threshold cutoff of the metabolites was set to 10, above this threshold, were filtered out as potential target biomarkers.
T5 647-783 Sentence denotes The VIP-value threshold cutoff of the metabolites was set to 10, above this threshold, were filtered out as potential target biomarkers.
TextSentencer_T6 784-907 Sentence denotes Sixteen distinct metabolites were identified from these pathways, and 6 of them can be considered for rational drug design.
T6 784-907 Sentence denotes Sixteen distinct metabolites were identified from these pathways, and 6 of them can be considered for rational drug design.
TextSentencer_T7 908-1090 Sentence denotes It was further experimental validation that the changes in metabolic profiling were restored to their baseline values after JuA treatment according to the multivariate data analysis.
T7 908-1090 Sentence denotes It was further experimental validation that the changes in metabolic profiling were restored to their baseline values after JuA treatment according to the multivariate data analysis.
TextSentencer_T8 1091-1277 Sentence denotes Potential metabolite network of the insomnia was preliminarily predicted JuA-target interaction networks, and could be further explored for in silico docking studies with suitable drugs.
T8 1091-1277 Sentence denotes Potential metabolite network of the insomnia was preliminarily predicted JuA-target interaction networks, and could be further explored for in silico docking studies with suitable drugs.
TextSentencer_T9 1278-1379 Sentence denotes Thus, our method is an efficient procedure for drug target identification through metabolic analysis.
T9 1278-1379 Sentence denotes Thus, our method is an efficient procedure for drug target identification through metabolic analysis.
TextSentencer_T10 1380-1542 Sentence denotes It can guide testable predictions, provide insights into drug action mechanisms and enable us to increase research productivity toward metabolomic drug discovery.
T10 1380-1542 Sentence denotes It can guide testable predictions, provide insights into drug action mechanisms and enable us to increase research productivity toward metabolomic drug discovery.