Id |
Subject |
Object |
Predicate |
Lexical cue |
TextSentencer_T1 |
0-118 |
Sentence |
denotes |
CysTRAQ - A combination of iTRAQ and enrichment of cysteinyl peptides for uncovering and quantifying hidden proteomes. |
T1 |
0-118 |
Sentence |
denotes |
CysTRAQ - A combination of iTRAQ and enrichment of cysteinyl peptides for uncovering and quantifying hidden proteomes. |
TextSentencer_T2 |
119-273 |
Sentence |
denotes |
Shotgun proteomics is capable of characterizing differences in both protein quality and quantity, and has been applied in various biomedical applications. |
T2 |
119-273 |
Sentence |
denotes |
Shotgun proteomics is capable of characterizing differences in both protein quality and quantity, and has been applied in various biomedical applications. |
TextSentencer_T3 |
274-437 |
Sentence |
denotes |
Unfortunately, the high complexity and dynamic range of proteins in studied samples, clinical in particular, often hinders the identification of relevant proteins. |
T3 |
274-437 |
Sentence |
denotes |
Unfortunately, the high complexity and dynamic range of proteins in studied samples, clinical in particular, often hinders the identification of relevant proteins. |
TextSentencer_T4 |
438-628 |
Sentence |
denotes |
Indeed, information-rich, low abundance proteins often remain undetected, whereas repeatedly reported altered concentrations in high abundance proteins are often ambiguous and insignificant. |
T4 |
438-628 |
Sentence |
denotes |
Indeed, information-rich, low abundance proteins often remain undetected, whereas repeatedly reported altered concentrations in high abundance proteins are often ambiguous and insignificant. |
TextSentencer_T5 |
629-751 |
Sentence |
denotes |
Several techniques have therefore been developed to overcome this obstacle and provide a deeper insight into the proteome. |
T5 |
629-751 |
Sentence |
denotes |
Several techniques have therefore been developed to overcome this obstacle and provide a deeper insight into the proteome. |
TextSentencer_T6 |
752-906 |
Sentence |
denotes |
Here we report a novel approach, which enables iTRAQ reagent quantitation of peptides fractionated based on presence of a cysteine residue (thus CysTRAQ). |
T6 |
752-906 |
Sentence |
denotes |
Here we report a novel approach, which enables iTRAQ reagent quantitation of peptides fractionated based on presence of a cysteine residue (thus CysTRAQ). |
TextSentencer_T7 |
907-1065 |
Sentence |
denotes |
For the first time, we prove that iTRAQ quantitation is fully compatible with cysteinyl peptide enrichment and is not influenced by the fractionation process. |
T7 |
907-1065 |
Sentence |
denotes |
For the first time, we prove that iTRAQ quantitation is fully compatible with cysteinyl peptide enrichment and is not influenced by the fractionation process. |
TextSentencer_T8 |
1066-1373 |
Sentence |
denotes |
Moreover, the employment of the method combined with high-resolution TripleTOF 5600 mass spectrometer for very fast MS/MS acquisition in human amniotic fluid analysis significantly increased the number of identified proteins, which were simultaneously quantified owing to the introduction of iTRAQ labeling. |
T8 |
1066-1373 |
Sentence |
denotes |
Moreover, the employment of the method combined with high-resolution TripleTOF 5600 mass spectrometer for very fast MS/MS acquisition in human amniotic fluid analysis significantly increased the number of identified proteins, which were simultaneously quantified owing to the introduction of iTRAQ labeling. |
TextSentencer_T9 |
1374-1560 |
Sentence |
denotes |
We herein show that CysTRAQ is a robust and straightforward method with potential application in quantitative proteomics experiments, i.e. as an alternative to the ICAT reagent approach. |
T9 |
1374-1560 |
Sentence |
denotes |
We herein show that CysTRAQ is a robust and straightforward method with potential application in quantitative proteomics experiments, i.e. as an alternative to the ICAT reagent approach. |