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PubMed:21657221 JSONTXT 24 Projects

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Id Subject Object Predicate Lexical cue
T1 0-120 Sentence denotes Expression profiling and regulation of genes related to silkworm posterior silk gland development and fibroin synthesis.
T1 0-120 Sentence denotes Expression profiling and regulation of genes related to silkworm posterior silk gland development and fibroin synthesis.
T2 121-269 Sentence denotes The posterior silk gland (PSG) is the most important suborgan responsible for the synthesis and secretion of silk core fibroin proteins in silkworm.
T2 121-269 Sentence denotes The posterior silk gland (PSG) is the most important suborgan responsible for the synthesis and secretion of silk core fibroin proteins in silkworm.
T3 270-504 Sentence denotes Here, we performed genome-scale expression profiling analysis of silkworm PSG at the fourth molting (M4) and at day 1 (V1), day 3 (V3), day 5 (V5), and wandering stage (W) of the fifth instar by microarray analysis with 22 987 probes.
T3 270-504 Sentence denotes Here, we performed genome-scale expression profiling analysis of silkworm PSG at the fourth molting (M4) and at day 1 (V1), day 3 (V3), day 5 (V5), and wandering stage (W) of the fifth instar by microarray analysis with 22 987 probes.
T4 505-746 Sentence denotes We found that the five genes of silk proteins secreted from PSG including fibroin heavy (H) and light (L) chains, P25, seroin 1, and seroin 2 basically showed obvious up-regulation at V3 which lasted to V5, while slight down-regulation at W.
T4 505-746 Sentence denotes We found that the five genes of silk proteins secreted from PSG including fibroin heavy (H) and light (L) chains, P25, seroin 1, and seroin 2 basically showed obvious up-regulation at V3 which lasted to V5, while slight down-regulation at W.
T5 747-941 Sentence denotes The expression of translation-related genes including ribosomal proteins and translation initiation factors generally remained stable from M4 to V5, whereas it showed clear down-regulation at W.
T5 747-941 Sentence denotes The expression of translation-related genes including ribosomal proteins and translation initiation factors generally remained stable from M4 to V5, whereas it showed clear down-regulation at W.
T6 942-1220 Sentence denotes Clustering analysis of the 643 significantly differentially expressed transcripts revealed that 43 of the important genes including seroin 1 and sugar transporter protein had co-expression patterns which were consistent with the rate changes of fibroin synthesis and PSG growth.
T6 942-1220 Sentence denotes Clustering analysis of the 643 significantly differentially expressed transcripts revealed that 43 of the important genes including seroin 1 and sugar transporter protein had co-expression patterns which were consistent with the rate changes of fibroin synthesis and PSG growth.
T7 1221-1335 Sentence denotes Pathway analysis disclosed that the genes in different clusters might have co-regulations and direct interactions.
T7 1221-1335 Sentence denotes Pathway analysis disclosed that the genes in different clusters might have co-regulations and direct interactions.
T8 1336-1416 Sentence denotes These genes were supposed to be involved in the fibroin synthesis and secretion.
T8 1336-1416 Sentence denotes These genes were supposed to be involved in the fibroin synthesis and secretion.
T9 1417-1568 Sentence denotes The differential expression of several hormone-related genes also suggested their functions on the regulation of PSG development and fibroin synthesis.
T9 1417-1568 Sentence denotes The differential expression of several hormone-related genes also suggested their functions on the regulation of PSG development and fibroin synthesis.
T10 1569-1804 Sentence denotes 2D gel-based proteomics and phosphoproteomics profiling revealed that the phosphorylated proteins accounted for no more than one-sixth of the total proteins at each stage, which was much lower than the level in normal eukaryotic cells.
T10 1569-1804 Sentence denotes 2D gel-based proteomics and phosphoproteomics profiling revealed that the phosphorylated proteins accounted for no more than one-sixth of the total proteins at each stage, which was much lower than the level in normal eukaryotic cells.
T11 1805-1993 Sentence denotes Changes in the phosphorylation status and levels of several proteins such as actin-depolymerizing factor 1 and enolase might be deeply involved in fibroin secretion and tissue development.
T11 1805-1993 Sentence denotes Changes in the phosphorylation status and levels of several proteins such as actin-depolymerizing factor 1 and enolase might be deeply involved in fibroin secretion and tissue development.
T12 1994-2339 Sentence denotes Shotgun proteomic profiling combined with label-free quantification analysis on the PSG at V3, V5, and W revealed that many small heat shock proteins (sHSP) were specially expressed at W, which was substantially consistent with the results from 2-DE analysis, and implied the close correlations of sHSP with the physiological states of PSG at W.
T12 1994-2339 Sentence denotes Shotgun proteomic profiling combined with label-free quantification analysis on the PSG at V3, V5, and W revealed that many small heat shock proteins (sHSP) were specially expressed at W, which was substantially consistent with the results from 2-DE analysis, and implied the close correlations of sHSP with the physiological states of PSG at W.
T13 2340-2588 Sentence denotes A majority of significantly up-regulated proteins at V5 were related to ribosome pathway, which was different from the microarray results, implying that the translation-level regulation of ribosomal proteins might be critical for fibroin synthesis.
T13 2340-2588 Sentence denotes A majority of significantly up-regulated proteins at V5 were related to ribosome pathway, which was different from the microarray results, implying that the translation-level regulation of ribosomal proteins might be critical for fibroin synthesis.
T14 2589-2787 Sentence denotes In contrast, the ubiquitin-proteasome pathway related proteins appeared obviously up-regulated at W, suggesting that the programmed cell death process of PSG cells might be started before cocooning.
T14 2589-2787 Sentence denotes In contrast, the ubiquitin-proteasome pathway related proteins appeared obviously up-regulated at W, suggesting that the programmed cell death process of PSG cells might be started before cocooning.