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PubMed:21385794 JSONTXT 71 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-114 Sentence denotes G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction.
T1 0-114 Sentence denotes G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction.
T1 0-114 Sentence denotes G6PC3 mutations are associated with a major defect of glycosylation: a novel mechanism for neutrophil dysfunction.
TextSentencer_T2 115-282 Sentence denotes Glucose-6-phosphatase, an enzyme localized in the endoplasmic reticulum (ER), catalyzes the hydrolysis of glucose-6-phosphate (G6P) to glucose and inorganic phosphate.
T2 115-282 Sentence denotes Glucose-6-phosphatase, an enzyme localized in the endoplasmic reticulum (ER), catalyzes the hydrolysis of glucose-6-phosphate (G6P) to glucose and inorganic phosphate.
T2 115-282 Sentence denotes Glucose-6-phosphatase, an enzyme localized in the endoplasmic reticulum (ER), catalyzes the hydrolysis of glucose-6-phosphate (G6P) to glucose and inorganic phosphate.
TextSentencer_T3 283-383 Sentence denotes In humans, there are three differentially expressed glucose-6-phosphatase catabolic genes (G6PC1-3).
T3 283-383 Sentence denotes In humans, there are three differentially expressed glucose-6-phosphatase catabolic genes (G6PC1-3).
T3 283-383 Sentence denotes In humans, there are three differentially expressed glucose-6-phosphatase catabolic genes (G6PC1-3).
TextSentencer_T4 384-533 Sentence denotes Recently, it has been shown that mutations in the G6PC3 gene result in a syndrome associating congenital neutropenia and various organ malformations.
T4 384-533 Sentence denotes Recently, it has been shown that mutations in the G6PC3 gene result in a syndrome associating congenital neutropenia and various organ malformations.
T4 384-533 Sentence denotes Recently, it has been shown that mutations in the G6PC3 gene result in a syndrome associating congenital neutropenia and various organ malformations.
TextSentencer_T5 534-644 Sentence denotes The enzymatic function of G6PC3 is dependent on G6P transport into the ER, mediated by G6P translocase (G6PT).
T5 534-644 Sentence denotes The enzymatic function of G6PC3 is dependent on G6P transport into the ER, mediated by G6P translocase (G6PT).
T5 534-644 Sentence denotes The enzymatic function of G6PC3 is dependent on G6P transport into the ER, mediated by G6P translocase (G6PT).
TextSentencer_T6 645-733 Sentence denotes Mutations in the gene encoding G6PT result in glycogen storage disease type-1b (GSD-1b).
T6 645-733 Sentence denotes Mutations in the gene encoding G6PT result in glycogen storage disease type-1b (GSD-1b).
T6 645-733 Sentence denotes Mutations in the gene encoding G6PT result in glycogen storage disease type-1b (GSD-1b).
TextSentencer_T7 734-851 Sentence denotes Interestingly, GSD-1b patients exhibit a similar neutrophil dysfunction to that observed in G6PC3-deficient patients.
T7 734-851 Sentence denotes Interestingly, GSD-1b patients exhibit a similar neutrophil dysfunction to that observed in G6PC3-deficient patients.
T7 734-851 Sentence denotes Interestingly, GSD-1b patients exhibit a similar neutrophil dysfunction to that observed in G6PC3-deficient patients.
TextSentencer_T8 852-1061 Sentence denotes To better understand the causes of neutrophil dysfunction in both diseases, we have studied the neutrophil nicotinamide adenine dinucleotide phosphate (NADPH) oxidase of patients with G6PC3 and G6PT syndromes.
T8 852-1061 Sentence denotes To better understand the causes of neutrophil dysfunction in both diseases, we have studied the neutrophil nicotinamide adenine dinucleotide phosphate (NADPH) oxidase of patients with G6PC3 and G6PT syndromes.
T8 852-1061 Sentence denotes To better understand the causes of neutrophil dysfunction in both diseases, we have studied the neutrophil nicotinamide adenine dinucleotide phosphate (NADPH) oxidase of patients with G6PC3 and G6PT syndromes.
TextSentencer_T9 1062-1273 Sentence denotes Unexpectedly, sodium dodecyl sulfate-polyacrylamide gel electrophoresis experiments indicated hypo-glycosylation of gp91(phox), the electron-transporting component of the NADPH oxidase, in all of these patients.
T9 1062-1273 Sentence denotes Unexpectedly, sodium dodecyl sulfate-polyacrylamide gel electrophoresis experiments indicated hypo-glycosylation of gp91(phox), the electron-transporting component of the NADPH oxidase, in all of these patients.
T9 1062-1273 Sentence denotes Unexpectedly, sodium dodecyl sulfate-polyacrylamide gel electrophoresis experiments indicated hypo-glycosylation of gp91(phox), the electron-transporting component of the NADPH oxidase, in all of these patients.
TextSentencer_T10 1274-1487 Sentence denotes Rigorous mass spectrometric glycomic profiling showed that most of the complex-type antennae which characterize the neutrophil N-glycome of healthy individuals were severely truncated in the patients' neutrophils.
T10 1274-1487 Sentence denotes Rigorous mass spectrometric glycomic profiling showed that most of the complex-type antennae which characterize the neutrophil N-glycome of healthy individuals were severely truncated in the patients' neutrophils.
T10 1274-1487 Sentence denotes Rigorous mass spectrometric glycomic profiling showed that most of the complex-type antennae which characterize the neutrophil N-glycome of healthy individuals were severely truncated in the patients' neutrophils.
TextSentencer_T11 1488-1569 Sentence denotes A comparable truncation of the core 2 antenna of the O-glycans was also observed.
T11 1488-1569 Sentence denotes A comparable truncation of the core 2 antenna of the O-glycans was also observed.
T11 1488-1569 Sentence denotes A comparable truncation of the core 2 antenna of the O-glycans was also observed.
TextSentencer_T12 1570-1770 Sentence denotes This aberrant neutrophil glycosylation is predicted to have profound effects on the neutrophil function and merit designation of both syndromes as a new class of congenital disorders of glycosylation.
T12 1570-1770 Sentence denotes This aberrant neutrophil glycosylation is predicted to have profound effects on the neutrophil function and merit designation of both syndromes as a new class of congenital disorders of glycosylation.
T12 1570-1770 Sentence denotes This aberrant neutrophil glycosylation is predicted to have profound effects on the neutrophil function and merit designation of both syndromes as a new class of congenital disorders of glycosylation.