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PubMed:21383697 JSONTXT 9 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-111 Sentence denotes MicroRNA-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways.
T1 0-111 Sentence denotes MicroRNA-mediated downregulation of mTOR/FGFR3 controls tumor growth induced by Src-related oncogenic pathways.
TextSentencer_T2 112-262 Sentence denotes The tyrosine kinase c-Src is upregulated in various human cancers, but the molecular mechanisms underlying c-Src-mediated tumor growth remain unclear.
T2 112-262 Sentence denotes The tyrosine kinase c-Src is upregulated in various human cancers, but the molecular mechanisms underlying c-Src-mediated tumor growth remain unclear.
TextSentencer_T3 263-344 Sentence denotes Here we examined the involvement of microRNAs in the c-Src-mediated tumor growth.
T3 263-344 Sentence denotes Here we examined the involvement of microRNAs in the c-Src-mediated tumor growth.
TextSentencer_T4 345-567 Sentence denotes Microarray profiling revealed that c-Src activation downregulates a limited set of microRNAs, including miR-99a, which targets oncogenic mammalian target of rapamycin (mTOR) and fibroblast growth factor receptor 3 (FGFR3).
T4 345-567 Sentence denotes Microarray profiling revealed that c-Src activation downregulates a limited set of microRNAs, including miR-99a, which targets oncogenic mammalian target of rapamycin (mTOR) and fibroblast growth factor receptor 3 (FGFR3).
TextSentencer_T5 568-704 Sentence denotes Re-expression of miR-99a suppressed tumor growth of c-Src-transformed cells, and this effect was restored by the overexpression of mTOR.
T5 568-704 Sentence denotes Re-expression of miR-99a suppressed tumor growth of c-Src-transformed cells, and this effect was restored by the overexpression of mTOR.
TextSentencer_T6 705-896 Sentence denotes The downregulation of miR-99a was also observed in epidermal growth factor- and Ras-transformed cells, and it was suppressed by inhibiting the mitogen-activated protein kinase (MAPK) pathway.
T6 705-896 Sentence denotes The downregulation of miR-99a was also observed in epidermal growth factor- and Ras-transformed cells, and it was suppressed by inhibiting the mitogen-activated protein kinase (MAPK) pathway.
TextSentencer_T7 897-1019 Sentence denotes Furthermore, miR-99a downregulation is associated with mTOR/FGFR3 upregulation in various human lung cancer cells/tissues.
T7 897-1019 Sentence denotes Furthermore, miR-99a downregulation is associated with mTOR/FGFR3 upregulation in various human lung cancer cells/tissues.
TextSentencer_T8 1020-1100 Sentence denotes The tumorigenicity of these cells was suppressed by the introduction of miR-99a.
T8 1020-1100 Sentence denotes The tumorigenicity of these cells was suppressed by the introduction of miR-99a.
TextSentencer_T9 1101-1296 Sentence denotes These findings suggest that the miR-99a-mTOR/FGFR3 pathway is crucial for controlling tumor growth in a wide range of human cancers that harbor upregulation of the Src-related oncogenic pathways.
T9 1101-1296 Sentence denotes These findings suggest that the miR-99a-mTOR/FGFR3 pathway is crucial for controlling tumor growth in a wide range of human cancers that harbor upregulation of the Src-related oncogenic pathways.