> top > projects > sentences > docs > PubMed:21365246 > annotations
sentences Home  

PubMed:21365246 JSONTXT 41 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-113 Sentence denotes Regulation of glycosyltransferases and Lewis antigens expression by IL-1β and IL-6 in human gastric cancer cells.
T1 0-113 Sentence denotes Regulation of glycosyltransferases and Lewis antigens expression by IL-1β and IL-6 in human gastric cancer cells.
TextSentencer_T2 114-304 Sentence denotes Inflammation of stomach mucosa has been postulated as initiator of gastric carcinogenesis and the presence of pro-inflammatory cytokines can regulate specific genes involved in this process.
T2 114-304 Sentence denotes Inflammation of stomach mucosa has been postulated as initiator of gastric carcinogenesis and the presence of pro-inflammatory cytokines can regulate specific genes involved in this process.
TextSentencer_T3 305-455 Sentence denotes The cellular expression pattern of glycosyltransferases and Lewis antigens detected in the normal mucosa changed during the neoplassic transformation.
T3 305-455 Sentence denotes The cellular expression pattern of glycosyltransferases and Lewis antigens detected in the normal mucosa changed during the neoplassic transformation.
TextSentencer_T4 456-639 Sentence denotes The aim of this work was to determine the regulation of specific fucosyltransferases and sialyltransferases by IL-1β and IL-6 pro-inflammatory cytokines in MKN45 gastric cancer cells.
T4 456-639 Sentence denotes The aim of this work was to determine the regulation of specific fucosyltransferases and sialyltransferases by IL-1β and IL-6 pro-inflammatory cytokines in MKN45 gastric cancer cells.
TextSentencer_T5 640-750 Sentence denotes IL-1β induced significant increases in the mRNA levels of FUT1, FUT2 and FUT4, and decreases of FUT3 and FUT5.
T5 640-750 Sentence denotes IL-1β induced significant increases in the mRNA levels of FUT1, FUT2 and FUT4, and decreases of FUT3 and FUT5.
TextSentencer_T6 751-839 Sentence denotes In IL-6 treatments, enhanced FUT1 and lower FUT3 and FUT5 mRNA expression were detected.
T6 751-839 Sentence denotes In IL-6 treatments, enhanced FUT1 and lower FUT3 and FUT5 mRNA expression were detected.
TextSentencer_T7 840-917 Sentence denotes No substantial changes were observed in the levels of ST3GalIII and ST3GalIV.
T7 840-917 Sentence denotes No substantial changes were observed in the levels of ST3GalIII and ST3GalIV.
TextSentencer_T8 918-1158 Sentence denotes The activation of FUT1, FUT2 and FUT4 by IL-1β is through the NF-κB pathway and the down-regulation of FUT3 and FUT5 by IL-6 is through the gp130/STAT-3 pathway, since they are inhibited specifically by panepoxydone and AG490, respectively.
T8 918-1158 Sentence denotes The activation of FUT1, FUT2 and FUT4 by IL-1β is through the NF-κB pathway and the down-regulation of FUT3 and FUT5 by IL-6 is through the gp130/STAT-3 pathway, since they are inhibited specifically by panepoxydone and AG490, respectively.
TextSentencer_T9 1159-1432 Sentence denotes The levels of Lewis antigens after IL-1β or IL-6 stimulation decreased for sialyl-Lewis x, and no significant differences were found in the rest of the Lewis antigens analyzed, as it was also observed in subcutaneous mice tumors from MKN45 cells treated with IL-1β or IL-6.
T9 1159-1432 Sentence denotes The levels of Lewis antigens after IL-1β or IL-6 stimulation decreased for sialyl-Lewis x, and no significant differences were found in the rest of the Lewis antigens analyzed, as it was also observed in subcutaneous mice tumors from MKN45 cells treated with IL-1β or IL-6.
TextSentencer_T10 1433-1576 Sentence denotes In addition, in 61 human intestinal-type gastric tumors, sialyl-Lewis x was highly detected in samples from patients that developed metastasis.
T10 1433-1576 Sentence denotes In addition, in 61 human intestinal-type gastric tumors, sialyl-Lewis x was highly detected in samples from patients that developed metastasis.
TextSentencer_T11 1577-1786 Sentence denotes These results indicate that the expression of the fucosyltransferases involved in the synthesis of Lewis antigens in gastric cancer cells can be specifically modulated by IL-1β and IL-6 inflammatory cytokines.
T11 1577-1786 Sentence denotes These results indicate that the expression of the fucosyltransferases involved in the synthesis of Lewis antigens in gastric cancer cells can be specifically modulated by IL-1β and IL-6 inflammatory cytokines.