> top > projects > sentences > docs > PubMed:20828385 > annotations
sentences Home  

PubMed:20828385 JSONTXT 32 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-90 Sentence denotes Cytostatic and anti-angiogenic effects of temsirolimus in refractory mantle cell lymphoma.
T1 0-90 Sentence denotes Cytostatic and anti-angiogenic effects of temsirolimus in refractory mantle cell lymphoma.
TextSentencer_T2 91-181 Sentence denotes Mantle cell lymphoma (MCL) is a rare and aggressive type of B-cell non-Hodgkin's lymphoma.
T2 91-181 Sentence denotes Mantle cell lymphoma (MCL) is a rare and aggressive type of B-cell non-Hodgkin's lymphoma.
TextSentencer_T3 182-281 Sentence denotes Patients become progressively refractory to conventional chemotherapy, and their prognosis is poor.
T3 182-281 Sentence denotes Patients become progressively refractory to conventional chemotherapy, and their prognosis is poor.
TextSentencer_T4 282-574 Sentence denotes However, a 38% remission rate has been recently reported in refractory MCL treated with temsirolimus, a mTOR inhibitor.Here we had the opportunity to study a case of refractory MCL who had tumor regression two months after temsirolimus treatment, and a progression-free survival of 10 months.
T4 282-574 Sentence denotes However, a 38% remission rate has been recently reported in refractory MCL treated with temsirolimus, a mTOR inhibitor.Here we had the opportunity to study a case of refractory MCL who had tumor regression two months after temsirolimus treatment, and a progression-free survival of 10 months.
TextSentencer_T5 575-673 Sentence denotes In this case, lymph node biopsies were performed before and six months after temsirolimus therapy.
T5 575-673 Sentence denotes In this case, lymph node biopsies were performed before and six months after temsirolimus therapy.
TextSentencer_T6 674-861 Sentence denotes Comparison of the two biopsies showed that temsirolimus inhibited tumor cell proliferation through cell cycle arrest, but did not induce any change in the number of apoptotic tumor cells.
T6 674-861 Sentence denotes Comparison of the two biopsies showed that temsirolimus inhibited tumor cell proliferation through cell cycle arrest, but did not induce any change in the number of apoptotic tumor cells.
TextSentencer_T7 862-1005 Sentence denotes Apart from this cytostatic effect, temsirolimus had an antiangiogenic effect with decrease of tumor microvessel density and of VEGF expression.
T7 862-1005 Sentence denotes Apart from this cytostatic effect, temsirolimus had an antiangiogenic effect with decrease of tumor microvessel density and of VEGF expression.
TextSentencer_T8 1006-1153 Sentence denotes Moreover, numerous patchy, well-limited fibrotic areas, compatible with post-necrotic tissue repair, were found after 6-month temsirolimus therapy.
T8 1006-1153 Sentence denotes Moreover, numerous patchy, well-limited fibrotic areas, compatible with post-necrotic tissue repair, were found after 6-month temsirolimus therapy.
TextSentencer_T9 1154-1411 Sentence denotes Thus, temsirolimus reduced tumor burden through associated cytostatic and anti-angiogenic effects.This dual effect of temsirolimus on tumor tissue could contribute to its recently reported efficiency in refractory MCL resistant to conventional chemotherapy.
T9 1154-1411 Sentence denotes Thus, temsirolimus reduced tumor burden through associated cytostatic and anti-angiogenic effects.This dual effect of temsirolimus on tumor tissue could contribute to its recently reported efficiency in refractory MCL resistant to conventional chemotherapy.