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PubMed:2026605 JSONTXT 32 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-54 Sentence denotes Tissue-specific expression of the platelet GPIIb gene.
T1 0-54 Sentence denotes Tissue-specific expression of the platelet GPIIb gene.
T2 55-238 Sentence denotes One of the major objectives in the study of thrombogenesis is to determine the mechanisms by which a hematopoietic progenitor is activated and committed to the megakaryocytic lineage.
T2 55-238 Sentence denotes One of the major objectives in the study of thrombogenesis is to determine the mechanisms by which a hematopoietic progenitor is activated and committed to the megakaryocytic lineage.
T3 239-480 Sentence denotes Recent development of primary cultures of human megakaryocytes and the molecular cloning of genes that are specific to this lineage offer the possibility of getting some insights into the genetic mechanisms that control megakaryocytopoiesis.
T3 239-480 Sentence denotes Recent development of primary cultures of human megakaryocytes and the molecular cloning of genes that are specific to this lineage offer the possibility of getting some insights into the genetic mechanisms that control megakaryocytopoiesis.
T4 481-756 Sentence denotes One gene of interest is the glycoprotein IIb (GPIIb) gene; GPIIb, the alpha subunit of the platelet cytoadhesin GPIIb-IIIa, is produced in megakaryocytes at an early stage of the differentiation, whereas the other subunit of this complex, GPIIIa, is expressed in other cells.
T4 481-756 Sentence denotes One gene of interest is the glycoprotein IIb (GPIIb) gene; GPIIb, the alpha subunit of the platelet cytoadhesin GPIIb-IIIa, is produced in megakaryocytes at an early stage of the differentiation, whereas the other subunit of this complex, GPIIIa, is expressed in other cells.
T5 757-897 Sentence denotes For these reasons, the 5'-flanking region of the GPIIb gene was used to identify the regions that interact with DNA-binding nuclear factors.
T5 757-897 Sentence denotes For these reasons, the 5'-flanking region of the GPIIb gene was used to identify the regions that interact with DNA-binding nuclear factors.
T6 898-1037 Sentence denotes A fragment extending from -643 to +33 is capable of controlling the tissue-specific expression of the CAT gene in transfection experiments.
T6 898-1037 Sentence denotes A fragment extending from -643 to +33 is capable of controlling the tissue-specific expression of the CAT gene in transfection experiments.
T7 1038-1204 Sentence denotes Within this region, we have identified several sequences that are implicated in DNA protein interactions as shown in DNAse I footprints and gel mobility shift assays.
T7 1038-1204 Sentence denotes Within this region, we have identified several sequences that are implicated in DNA protein interactions as shown in DNAse I footprints and gel mobility shift assays.
T8 1205-1343 Sentence denotes One region, centered at -54, is similar to a nuclear factor E1-binding site, and a region located at position -233 contains a CCAAT motif.
T8 1205-1343 Sentence denotes One region, centered at -54, is similar to a nuclear factor E1-binding site, and a region located at position -233 contains a CCAAT motif.
T9 1344-1491 Sentence denotes Two domains centered at positions -345 and -540, respectively, bind proteins that are present in megakaryocytic cells and nonrelated cells as well.
T9 1344-1491 Sentence denotes Two domains centered at positions -345 and -540, respectively, bind proteins that are present in megakaryocytic cells and nonrelated cells as well.
T10 1492-1625 Sentence denotes Finally, two other domains, located at positions -460 and -510, interact with proteins that are only present in megakaryocytic cells.
T10 1492-1625 Sentence denotes Finally, two other domains, located at positions -460 and -510, interact with proteins that are only present in megakaryocytic cells.
T11 1626-1750 Sentence denotes In addition, deletion of the region containing these two domains results in a significant decrease of the promoter activity.
T11 1626-1750 Sentence denotes In addition, deletion of the region containing these two domains results in a significant decrease of the promoter activity.
T12 1751-1874 Sentence denotes It is very likely that these domains bind megakaryocyte-specific nuclear proteins acting as positive transcription factors.
T12 1751-1874 Sentence denotes It is very likely that these domains bind megakaryocyte-specific nuclear proteins acting as positive transcription factors.