> top > projects > sentences > docs > PubMed:2019586 > annotations
sentences Home  

PubMed:2019586 JSONTXT 28 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-28 Sentence denotes Sulfatide activator protein.
T1 0-28 Sentence denotes Sulfatide activator protein.
TextSentencer_T2 29-139 Sentence denotes Alternative splicing that generates three mRNAs and a newly found mutation responsible for a clinical disease.
T2 29-139 Sentence denotes Alternative splicing that generates three mRNAs and a newly found mutation responsible for a clinical disease.
TextSentencer_T3 140-276 Sentence denotes The sulfatide activator protein, also known as SAP-1, is derived from a gene that generates an mRNA coding for four homologous proteins.
T3 140-276 Sentence denotes The sulfatide activator protein, also known as SAP-1, is derived from a gene that generates an mRNA coding for four homologous proteins.
TextSentencer_T4 277-371 Sentence denotes Its physiological function is to stimulate hydrolysis of sulfatide by arylsulfatase A in vivo.
T4 277-371 Sentence denotes Its physiological function is to stimulate hydrolysis of sulfatide by arylsulfatase A in vivo.
TextSentencer_T5 372-561 Sentence denotes A genetic defect in the sulfatide activator results in a metabolic disorder similar to classical metachromatic leukodystrophy, which is itself caused by a genetic defect in arylsulfatase A.
T5 372-561 Sentence denotes A genetic defect in the sulfatide activator results in a metabolic disorder similar to classical metachromatic leukodystrophy, which is itself caused by a genetic defect in arylsulfatase A.
TextSentencer_T6 562-838 Sentence denotes In a patient with sulfatide activator deficiency, a nucleotide transversion G722----C (counted from A of the initiation codon ATG) was found in the mRNA of the sulfatide activator precursor, resulting in the substitution of serine for Cys241 in the mature sulfatide activator.
T6 562-838 Sentence denotes In a patient with sulfatide activator deficiency, a nucleotide transversion G722----C (counted from A of the initiation codon ATG) was found in the mRNA of the sulfatide activator precursor, resulting in the substitution of serine for Cys241 in the mature sulfatide activator.
TextSentencer_T7 839-995 Sentence denotes The remainder of the coding sequence was completely normal except for a polymorphism C to T in position 1389, which does not change the amino acid sequence.
T7 839-995 Sentence denotes The remainder of the coding sequence was completely normal except for a polymorphism C to T in position 1389, which does not change the amino acid sequence.
TextSentencer_T8 996-1074 Sentence denotes The patient produces at least three different forms of mRNA for the precursor.
T8 996-1074 Sentence denotes The patient produces at least three different forms of mRNA for the precursor.
TextSentencer_T9 1075-1196 Sentence denotes Two of them include a stretch of an additional 9 and 6 bases, respectively, within the sulfatide activator coding region.
T9 1075-1196 Sentence denotes Two of them include a stretch of an additional 9 and 6 bases, respectively, within the sulfatide activator coding region.
TextSentencer_T10 1197-1275 Sentence denotes In normal individuals this stretch of additional bases has also been observed.
T10 1197-1275 Sentence denotes In normal individuals this stretch of additional bases has also been observed.
TextSentencer_T11 1276-1451 Sentence denotes This could be explained by the presence of a small 9-base pair exon which can be introduced, or not, by alternative splicing as a stretch of 9 or 6 bases into the mature mRNA.
T11 1276-1451 Sentence denotes This could be explained by the presence of a small 9-base pair exon which can be introduced, or not, by alternative splicing as a stretch of 9 or 6 bases into the mature mRNA.
TextSentencer_T12 1452-1569 Sentence denotes The shortest form of the mRNA yields an active sulfatide activator (Fürst, W., Schubert, J., Machleidt, W., Meier, H.
T12 1452-1569 Sentence denotes The shortest form of the mRNA yields an active sulfatide activator (Fürst, W., Schubert, J., Machleidt, W., Meier, H.
TextSentencer_T13 1570-1602 Sentence denotes E., and Sandhoff, K. (1990) Eur.
T13 1570-1602 Sentence denotes E., and Sandhoff, K. (1990) Eur.
TextSentencer_T14 1603-1605 Sentence denotes J.
T14 1603-1605 Sentence denotes J.
TextSentencer_T15 1606-1614 Sentence denotes Biochem.
T15 1606-1614 Sentence denotes Biochem.
TextSentencer_T16 1615-1629 Sentence denotes 192, 709-714).
T16 1615-1629 Sentence denotes 192, 709-714).