| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-74 |
Sentence |
denotes |
The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine. |
| T1 |
0-74 |
Sentence |
denotes |
The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine. |
| T1 |
0-74 |
Sentence |
denotes |
The novel proapoptotic activity of nonnatural enantiomer of Lentiginosine. |
| TextSentencer_T2 |
75-291 |
Sentence |
denotes |
D-(-)-Lentiginosine [(-)-4], the nonnatural enantiomer of the iminosugar indolizidine alkaloid L-(+)-lentiginosine, acts as apoptosis inducer on tumor cells of different origin, in contrast to its natural enantiomer. |
| T2 |
75-291 |
Sentence |
denotes |
D-(-)-Lentiginosine [(-)-4], the nonnatural enantiomer of the iminosugar indolizidine alkaloid L-(+)-lentiginosine, acts as apoptosis inducer on tumor cells of different origin, in contrast to its natural enantiomer. |
| T2 |
75-291 |
Sentence |
denotes |
D-(-)-Lentiginosine [(-)-4], the nonnatural enantiomer of the iminosugar indolizidine alkaloid L-(+)-lentiginosine, acts as apoptosis inducer on tumor cells of different origin, in contrast to its natural enantiomer. |
| TextSentencer_T3 |
292-482 |
Sentence |
denotes |
Although D-(-)-4 exhibited a proapoptotic activity towards tumor cells at level lower than the chemotherapeutic agent, SN38, it was less proapoptotic towards normal cells and less cytotoxic. |
| T3 |
292-482 |
Sentence |
denotes |
Although D-(-)-4 exhibited a proapoptotic activity towards tumor cells at level lower than the chemotherapeutic agent, SN38, it was less proapoptotic towards normal cells and less cytotoxic. |
| T3 |
292-482 |
Sentence |
denotes |
Although D-(-)-4 exhibited a proapoptotic activity towards tumor cells at level lower than the chemotherapeutic agent, SN38, it was less proapoptotic towards normal cells and less cytotoxic. |
| TextSentencer_T4 |
483-702 |
Sentence |
denotes |
Apoptosis induced by D-(-)-4 was caspase-dependent, as shown by the increased expression and activity of caspase-3 and -8 in treated cells, and by inhibition following treatment with the pan caspase inhibitor, ZVAD-FMK. |
| T4 |
483-702 |
Sentence |
denotes |
Apoptosis induced by D-(-)-4 was caspase-dependent, as shown by the increased expression and activity of caspase-3 and -8 in treated cells, and by inhibition following treatment with the pan caspase inhibitor, ZVAD-FMK. |
| T4 |
483-702 |
Sentence |
denotes |
Apoptosis induced by D-(-)-4 was caspase-dependent, as shown by the increased expression and activity of caspase-3 and -8 in treated cells, and by inhibition following treatment with the pan caspase inhibitor, ZVAD-FMK. |
| TextSentencer_T5 |
703-978 |
Sentence |
denotes |
This study highlighted how a natural iminosugar alkaloid and its synthetic enantiomer, which were simply known for their inhibition against a fungal glucoamylase, could behave in a complete different way when tested towards cell growth and death of cells of different origin. |
| T5 |
703-978 |
Sentence |
denotes |
This study highlighted how a natural iminosugar alkaloid and its synthetic enantiomer, which were simply known for their inhibition against a fungal glucoamylase, could behave in a complete different way when tested towards cell growth and death of cells of different origin. |
| T5 |
703-978 |
Sentence |
denotes |
This study highlighted how a natural iminosugar alkaloid and its synthetic enantiomer, which were simply known for their inhibition against a fungal glucoamylase, could behave in a complete different way when tested towards cell growth and death of cells of different origin. |