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PubMed:20053627 JSONTXT 65 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-71 Sentence denotes Heparan sulfate mediates amyloid-beta internalization and cytotoxicity.
T1 0-71 Sentence denotes Heparan sulfate mediates amyloid-beta internalization and cytotoxicity.
T1 0-71 Sentence denotes Heparan sulfate mediates amyloid-beta internalization and cytotoxicity.
TextSentencer_T2 72-284 Sentence denotes Heparan sulfate (HS) has been found associated with amyloid deposits, including the toxic amyloid-beta (Abeta) peptide aggregates in cerebral vasculature and neuronal tissues in patients with Alzheimer's disease.
T2 72-284 Sentence denotes Heparan sulfate (HS) has been found associated with amyloid deposits, including the toxic amyloid-beta (Abeta) peptide aggregates in cerebral vasculature and neuronal tissues in patients with Alzheimer's disease.
T2 72-284 Sentence denotes Heparan sulfate (HS) has been found associated with amyloid deposits, including the toxic amyloid-beta (Abeta) peptide aggregates in cerebral vasculature and neuronal tissues in patients with Alzheimer's disease.
TextSentencer_T3 285-379 Sentence denotes However, the pathophysiological significance of the HS-Abeta interaction has remained unclear.
T3 285-379 Sentence denotes However, the pathophysiological significance of the HS-Abeta interaction has remained unclear.
T3 285-379 Sentence denotes However, the pathophysiological significance of the HS-Abeta interaction has remained unclear.
TextSentencer_T4 380-492 Sentence denotes In the present study, we applied cell models to gain insight into the roles of HS in relation to Abeta toxicity.
T4 380-492 Sentence denotes In the present study, we applied cell models to gain insight into the roles of HS in relation to Abeta toxicity.
T4 380-492 Sentence denotes In the present study, we applied cell models to gain insight into the roles of HS in relation to Abeta toxicity.
TextSentencer_T5 493-668 Sentence denotes Wild-type Chinese hamster ovary (CHO-WT) cells showed loss of viability following exposure to Abeta40, whereas the HS-deficient cell line, pgsD-677, was essentially resistant.
T5 493-668 Sentence denotes Wild-type Chinese hamster ovary (CHO-WT) cells showed loss of viability following exposure to Abeta40, whereas the HS-deficient cell line, pgsD-677, was essentially resistant.
T5 493-668 Sentence denotes Wild-type Chinese hamster ovary (CHO-WT) cells showed loss of viability following exposure to Abeta40, whereas the HS-deficient cell line, pgsD-677, was essentially resistant.
TextSentencer_T6 669-760 Sentence denotes Immunocytochemical analysis showed Abeta internalization by CHO-WT, but not pgsD-677 cells.
T6 669-760 Sentence denotes Immunocytochemical analysis showed Abeta internalization by CHO-WT, but not pgsD-677 cells.
T6 669-760 Sentence denotes Immunocytochemical analysis showed Abeta internalization by CHO-WT, but not pgsD-677 cells.
TextSentencer_T7 761-856 Sentence denotes Abeta40 toxicity was also attenuated in human embryonic kidney cells overexpressing heparanase.
T7 761-856 Sentence denotes Abeta40 toxicity was also attenuated in human embryonic kidney cells overexpressing heparanase.
T7 761-856 Sentence denotes Abeta40 toxicity was also attenuated in human embryonic kidney cells overexpressing heparanase.
TextSentencer_T8 857-1008 Sentence denotes Finally, addition of heparin to human umbilical vein endothelial cells prevented internalization of added Abeta40 and protected against Abeta toxicity.
T8 857-1008 Sentence denotes Finally, addition of heparin to human umbilical vein endothelial cells prevented internalization of added Abeta40 and protected against Abeta toxicity.
T8 857-1008 Sentence denotes Finally, addition of heparin to human umbilical vein endothelial cells prevented internalization of added Abeta40 and protected against Abeta toxicity.
TextSentencer_T9 1009-1113 Sentence denotes Taken together, these findings suggest that cell-surface HS mediates Abeta internalization and toxicity.
T9 1009-1113 Sentence denotes Taken together, these findings suggest that cell-surface HS mediates Abeta internalization and toxicity.
T9 1009-1113 Sentence denotes Taken together, these findings suggest that cell-surface HS mediates Abeta internalization and toxicity.