Id |
Subject |
Object |
Predicate |
Lexical cue |
TextSentencer_T1 |
0-54 |
Sentence |
denotes |
KSHV downregulation of galectin-3 in Kaposi's sarcoma. |
T1 |
0-54 |
Sentence |
denotes |
KSHV downregulation of galectin-3 in Kaposi's sarcoma. |
T1 |
0-54 |
Sentence |
denotes |
KSHV downregulation of galectin-3 in Kaposi's sarcoma. |
TextSentencer_T2 |
55-161 |
Sentence |
denotes |
Galectins are a family of proteins that share an affinity for beta-galactoside containing glycoconjugates. |
T2 |
55-161 |
Sentence |
denotes |
Galectins are a family of proteins that share an affinity for beta-galactoside containing glycoconjugates. |
T2 |
55-161 |
Sentence |
denotes |
Galectins are a family of proteins that share an affinity for beta-galactoside containing glycoconjugates. |
TextSentencer_T3 |
162-283 |
Sentence |
denotes |
In prostate, ovarian and breast cancer, downregulation of galectin-3 is associated with malignancy and tumor progression. |
T3 |
162-283 |
Sentence |
denotes |
In prostate, ovarian and breast cancer, downregulation of galectin-3 is associated with malignancy and tumor progression. |
T3 |
162-283 |
Sentence |
denotes |
In prostate, ovarian and breast cancer, downregulation of galectin-3 is associated with malignancy and tumor progression. |
TextSentencer_T4 |
284-531 |
Sentence |
denotes |
Kaposi's sarcoma (KS) is characterized as an angioproliferative tumor of vascular endothelial cells and produces rare B cell lymphoproliferative diseases in the form of primary effusion lymphomas and some forms of multicentric Castleman's disease. |
T4 |
284-531 |
Sentence |
denotes |
Kaposi's sarcoma (KS) is characterized as an angioproliferative tumor of vascular endothelial cells and produces rare B cell lymphoproliferative diseases in the form of primary effusion lymphomas and some forms of multicentric Castleman's disease. |
T4 |
284-531 |
Sentence |
denotes |
Kaposi's sarcoma (KS) is characterized as an angioproliferative tumor of vascular endothelial cells and produces rare B cell lymphoproliferative diseases in the form of primary effusion lymphomas and some forms of multicentric Castleman's disease. |
TextSentencer_T5 |
532-610 |
Sentence |
denotes |
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent of KS. |
T5 |
532-610 |
Sentence |
denotes |
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent of KS. |
T5 |
532-610 |
Sentence |
denotes |
Kaposi's sarcoma-associated herpesvirus (KSHV) is the etiological agent of KS. |
TextSentencer_T6 |
611-830 |
Sentence |
denotes |
We found reduced levels of galectin-3 expression in a significant fraction of latency-associated nuclear antigen (LANA)-positive spindle cell regions in human archival KS tissue and as measured in KS tissue microarrays. |
T6 |
611-830 |
Sentence |
denotes |
We found reduced levels of galectin-3 expression in a significant fraction of latency-associated nuclear antigen (LANA)-positive spindle cell regions in human archival KS tissue and as measured in KS tissue microarrays. |
T6 |
611-830 |
Sentence |
denotes |
We found reduced levels of galectin-3 expression in a significant fraction of latency-associated nuclear antigen (LANA)-positive spindle cell regions in human archival KS tissue and as measured in KS tissue microarrays. |
TextSentencer_T7 |
831-1023 |
Sentence |
denotes |
Here we demonstrate that galectin-3 protein expression is downregulated 10-fold in 10-day KSHV-infected dermal microvascular endothelial cells (DMVEC) accompanied by downregulation of message. |
T7 |
831-1023 |
Sentence |
denotes |
Here we demonstrate that galectin-3 protein expression is downregulated 10-fold in 10-day KSHV-infected dermal microvascular endothelial cells (DMVEC) accompanied by downregulation of message. |
T7 |
831-1023 |
Sentence |
denotes |
Here we demonstrate that galectin-3 protein expression is downregulated 10-fold in 10-day KSHV-infected dermal microvascular endothelial cells (DMVEC) accompanied by downregulation of message. |
TextSentencer_T8 |
1024-1152 |
Sentence |
denotes |
There is loss of galectin-3 staining in KSHV-infected DMVEC by dual labeled immunohistochemistry in LANA-positive spindle cells. |
T8 |
1024-1152 |
Sentence |
denotes |
There is loss of galectin-3 staining in KSHV-infected DMVEC by dual labeled immunohistochemistry in LANA-positive spindle cells. |
T8 |
1024-1152 |
Sentence |
denotes |
There is loss of galectin-3 staining in KSHV-infected DMVEC by dual labeled immunohistochemistry in LANA-positive spindle cells. |
TextSentencer_T9 |
1153-1247 |
Sentence |
denotes |
We observed a consistent downregulation of galectin-3 by time-course transcriptional analysis. |
T9 |
1153-1247 |
Sentence |
denotes |
We observed a consistent downregulation of galectin-3 by time-course transcriptional analysis. |
T9 |
1153-1247 |
Sentence |
denotes |
We observed a consistent downregulation of galectin-3 by time-course transcriptional analysis. |
TextSentencer_T10 |
1248-1336 |
Sentence |
denotes |
Of the galectins assayed, only galectin-1 was also downregulated in KSHV-infected DMVEC. |
T10 |
1248-1336 |
Sentence |
denotes |
Of the galectins assayed, only galectin-1 was also downregulated in KSHV-infected DMVEC. |
T10 |
1248-1336 |
Sentence |
denotes |
Of the galectins assayed, only galectin-1 was also downregulated in KSHV-infected DMVEC. |
TextSentencer_T11 |
1337-1418 |
Sentence |
denotes |
We examined 86 KS tumors; 19 were LANA positive (22%) and 67 LANA negative (78%). |
T11 |
1337-1418 |
Sentence |
denotes |
We examined 86 KS tumors; 19 were LANA positive (22%) and 67 LANA negative (78%). |
T11 |
1337-1418 |
Sentence |
denotes |
We examined 86 KS tumors; 19 were LANA positive (22%) and 67 LANA negative (78%). |
TextSentencer_T12 |
1419-1558 |
Sentence |
denotes |
All 86 tumors were found to be galectin-3 positive; 11 of 19 showed reduced expression of galectin-3 in LANA-positive spindle cell regions. |
T12 |
1419-1558 |
Sentence |
denotes |
All 86 tumors were found to be galectin-3 positive; 11 of 19 showed reduced expression of galectin-3 in LANA-positive spindle cell regions. |
T12 |
1419-1558 |
Sentence |
denotes |
All 86 tumors were found to be galectin-3 positive; 11 of 19 showed reduced expression of galectin-3 in LANA-positive spindle cell regions. |
TextSentencer_T13 |
1559-1657 |
Sentence |
denotes |
Our data suggest that KSHV vFLIP and LANA are the viral genes targeting galectin-3 downregulation. |
T13 |
1559-1657 |
Sentence |
denotes |
Our data suggest that KSHV vFLIP and LANA are the viral genes targeting galectin-3 downregulation. |
T13 |
1559-1657 |
Sentence |
denotes |
Our data suggest that KSHV vFLIP and LANA are the viral genes targeting galectin-3 downregulation. |
TextSentencer_T14 |
1658-1804 |
Sentence |
denotes |
The contribution of host factors to the pathogenesis of KS is essential for early detection and development of innovative therapies for treatment. |
T14 |
1658-1804 |
Sentence |
denotes |
The contribution of host factors to the pathogenesis of KS is essential for early detection and development of innovative therapies for treatment. |
T14 |
1658-1804 |
Sentence |
denotes |
The contribution of host factors to the pathogenesis of KS is essential for early detection and development of innovative therapies for treatment. |