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PubMed:1985913 JSONTXT 40 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-88 Sentence denotes Transcriptional activation and nuclear targeting signals of the human androgen receptor.
T1 0-88 Sentence denotes Transcriptional activation and nuclear targeting signals of the human androgen receptor.
T2 89-235 Sentence denotes The androgen receptor (AR) is a signal-transducing protein required for sexual differentiation, development, and expression of the male phenotype.
T2 89-235 Sentence denotes The androgen receptor (AR) is a signal-transducing protein required for sexual differentiation, development, and expression of the male phenotype.
T3 236-475 Sentence denotes A series of human AR deletion mutants were created either by site-directed mutagenesis using restriction enzyme digestion, the polymerase chain reaction, or, for a series of unidirectional NH2-terminal deletions, exonuclease III digestion.
T3 236-475 Sentence denotes A series of human AR deletion mutants were created either by site-directed mutagenesis using restriction enzyme digestion, the polymerase chain reaction, or, for a series of unidirectional NH2-terminal deletions, exonuclease III digestion.
T4 476-663 Sentence denotes Receptor mutants were expressed in monkey kidney COS cells as truncated AR proteins between 20 and 107 kDa as revealed on immunoblots, where wild type AR was a doublet of 114 and 108 kDa.
T4 476-663 Sentence denotes Receptor mutants were expressed in monkey kidney COS cells as truncated AR proteins between 20 and 107 kDa as revealed on immunoblots, where wild type AR was a doublet of 114 and 108 kDa.
T5 664-816 Sentence denotes Subcellular localization by immunocytochemical staining demonstrated androgen-dependent nuclear uptake of AR from a perinuclear region of the cytoplasm.
T5 664-816 Sentence denotes Subcellular localization by immunocytochemical staining demonstrated androgen-dependent nuclear uptake of AR from a perinuclear region of the cytoplasm.
T6 817-1016 Sentence denotes A nuclear targeting signal similar in sequence and position to the glucocorticoid receptor and homologous to the SV40 large T antigen was required for androgen-induced nuclear uptake of wild type AR.
T6 817-1016 Sentence denotes A nuclear targeting signal similar in sequence and position to the glucocorticoid receptor and homologous to the SV40 large T antigen was required for androgen-induced nuclear uptake of wild type AR.
T7 1017-1150 Sentence denotes AR mutants lacking the NH2-terminal and/or steroid binding domains were constitutively nuclear with reduced transcriptional activity.
T7 1017-1150 Sentence denotes AR mutants lacking the NH2-terminal and/or steroid binding domains were constitutively nuclear with reduced transcriptional activity.
T8 1151-1363 Sentence denotes Transcriptional activation by wild type AR was androgen-dependent in cotransfection studies of CV1 cells using the chloramphenicol acetyltransferase reporter gene linked to the mouse mammary tumor virus promoter.
T8 1151-1363 Sentence denotes Transcriptional activation by wild type AR was androgen-dependent in cotransfection studies of CV1 cells using the chloramphenicol acetyltransferase reporter gene linked to the mouse mammary tumor virus promoter.
T9 1364-1599 Sentence denotes Deletion mutagenesis revealed within the NH2-terminal region a domain required for full transcriptional activity and within the steroid binding domain, an inhibitory function, deletion of which yielded a constitutively active receptor.
T9 1364-1599 Sentence denotes Deletion mutagenesis revealed within the NH2-terminal region a domain required for full transcriptional activity and within the steroid binding domain, an inhibitory function, deletion of which yielded a constitutively active receptor.
T10 1600-1764 Sentence denotes Inhibition of wild type AR by coexpression with an inactive NH2-terminal fragment suggested competition for nuclear factors required for transcriptional regulation.
T10 1600-1764 Sentence denotes Inhibition of wild type AR by coexpression with an inactive NH2-terminal fragment suggested competition for nuclear factors required for transcriptional regulation.
T11 1765-1882 Sentence denotes These studies demonstrate a concerted interplay among the domains of the AR protein in regulating gene transcription.
T11 1765-1882 Sentence denotes These studies demonstrate a concerted interplay among the domains of the AR protein in regulating gene transcription.