PubMed:19805545 / 672-1064 3 Projects
Annnotations
Id | Subject | Object | Predicate | Lexical cue |
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T6 | 0-392 | Sentence | denotes | However, active site-disabled ERK mutants (ERK1-K71R, ERK2-K52R, and ERK2-D147A), which competitively inhibit activation of endogenous ERK1/2, could not block Raf/MEK-induced growth arrest as well as changes in the cell cycle regulators, although they effectively blocked phosphorylation of the ERK1/2 catalytic activity readouts, p90(RSK) and ELK1, as well as the cell type-specific changes. |