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PubMed:19528665 JSONTXT 67 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-136 Sentence denotes A newly generated functional antibody identifies Tn antigen as a novel determinant in the cancer cell-lymphatic endothelium interaction.
T1 0-136 Sentence denotes A newly generated functional antibody identifies Tn antigen as a novel determinant in the cancer cell-lymphatic endothelium interaction.
T1 0-136 Sentence denotes A newly generated functional antibody identifies Tn antigen as a novel determinant in the cancer cell-lymphatic endothelium interaction.
TextSentencer_T2 137-253 Sentence denotes Malignant transformation of epithelial cells is frequently associated with the alteration of glycosylation pathways.
T2 137-253 Sentence denotes Malignant transformation of epithelial cells is frequently associated with the alteration of glycosylation pathways.
T2 137-253 Sentence denotes Malignant transformation of epithelial cells is frequently associated with the alteration of glycosylation pathways.
TextSentencer_T3 254-417 Sentence denotes Tn is a common tumor-associated carbohydrate antigen present in 90% of human carcinomas and its expression correlates with metastatic potential and poor prognosis.
T3 254-417 Sentence denotes Tn is a common tumor-associated carbohydrate antigen present in 90% of human carcinomas and its expression correlates with metastatic potential and poor prognosis.
T3 254-417 Sentence denotes Tn is a common tumor-associated carbohydrate antigen present in 90% of human carcinomas and its expression correlates with metastatic potential and poor prognosis.
TextSentencer_T4 418-572 Sentence denotes Despite its relevance, the functional role of Tn in tumor biology has not been firmly established probably for the lack of appropriate experimental tools.
T4 418-572 Sentence denotes Despite its relevance, the functional role of Tn in tumor biology has not been firmly established probably for the lack of appropriate experimental tools.
T4 418-572 Sentence denotes Despite its relevance, the functional role of Tn in tumor biology has not been firmly established probably for the lack of appropriate experimental tools.
TextSentencer_T5 573-814 Sentence denotes Our aims were to produce highly reactive monoclonal antibodies against Tn making use of synthetically produced Tn and to test their usefulness for in vivo imaging as well as to define their potential functional activity in tumor cell spread.
T5 573-814 Sentence denotes Our aims were to produce highly reactive monoclonal antibodies against Tn making use of synthetically produced Tn and to test their usefulness for in vivo imaging as well as to define their potential functional activity in tumor cell spread.
T5 573-814 Sentence denotes Our aims were to produce highly reactive monoclonal antibodies against Tn making use of synthetically produced Tn and to test their usefulness for in vivo imaging as well as to define their potential functional activity in tumor cell spread.
TextSentencer_T6 815-936 Sentence denotes We immunized mice with Tn clustered on cationized BSA and screened the positive hybridomas with Tn-biotinylated alginate.
T6 815-936 Sentence denotes We immunized mice with Tn clustered on cationized BSA and screened the positive hybridomas with Tn-biotinylated alginate.
T6 815-936 Sentence denotes We immunized mice with Tn clustered on cationized BSA and screened the positive hybridomas with Tn-biotinylated alginate.
TextSentencer_T7 937-1222 Sentence denotes Enzyme-linked immuno sorbent assay and immunofluorescence assays revealed that the most reactive anti-Tn IgM mAb (2154F12A4) selectively recognized Tn on the MCF7 breast cancer cell line since its binding to the cell membrane was completely abolished by preincubation with purified Tn.
T7 937-1222 Sentence denotes Enzyme-linked immuno sorbent assay and immunofluorescence assays revealed that the most reactive anti-Tn IgM mAb (2154F12A4) selectively recognized Tn on the MCF7 breast cancer cell line since its binding to the cell membrane was completely abolished by preincubation with purified Tn.
T7 937-1380 Sentence denotes Enzyme-linked immuno sorbent assay and immunofluorescence assays revealed that the most reactive anti-Tn IgM mAb (2154F12A4) selectively recognized Tn on the MCF7 breast cancer cell line since its binding to the cell membrane was completely abolished by preincubation with purified Tn. Importantly, QDot 800-conjugated mAb injected in MCF7-tumor bearing mice specifically bound to primary tumor lesions as well as to metastases in lymph nodes.
TextSentencer_T8 1223-1380 Sentence denotes Importantly, QDot 800-conjugated mAb injected in MCF7-tumor bearing mice specifically bound to primary tumor lesions as well as to metastases in lymph nodes.
T8 1223-1380 Sentence denotes Importantly, QDot 800-conjugated mAb injected in MCF7-tumor bearing mice specifically bound to primary tumor lesions as well as to metastases in lymph nodes.
TextSentencer_T9 1381-1626 Sentence denotes In addition, this mAb was able to inhibit cancer cell adhesion to lymphatic endothelium suggesting a novel involvement of Tn in the lymphatic dissemination of cancer cells and hypothesizing future applications in inhibiting lymphatic metastases.
T8 1381-1626 Sentence denotes In addition, this mAb was able to inhibit cancer cell adhesion to lymphatic endothelium suggesting a novel involvement of Tn in the lymphatic dissemination of cancer cells and hypothesizing future applications in inhibiting lymphatic metastases.
T9 1381-1626 Sentence denotes In addition, this mAb was able to inhibit cancer cell adhesion to lymphatic endothelium suggesting a novel involvement of Tn in the lymphatic dissemination of cancer cells and hypothesizing future applications in inhibiting lymphatic metastases.