| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-84 |
Sentence |
denotes |
Influence of insulin resistance on adiponectin receptor expression in breast cancer. |
| T1 |
0-84 |
Sentence |
denotes |
Influence of insulin resistance on adiponectin receptor expression in breast cancer. |
| TextSentencer_T2 |
85-95 |
Sentence |
denotes |
OBJECTIVE: |
| T2 |
85-95 |
Sentence |
denotes |
OBJECTIVE: |
| TextSentencer_T3 |
96-176 |
Sentence |
denotes |
Adipositas and insulin resistance are modifiable risk factors for breast cancer. |
| T3 |
96-176 |
Sentence |
denotes |
Adipositas and insulin resistance are modifiable risk factors for breast cancer. |
| TextSentencer_T4 |
177-244 |
Sentence |
denotes |
Adiponectin seems to be an important linkage of these associations. |
| T4 |
177-244 |
Sentence |
denotes |
Adiponectin seems to be an important linkage of these associations. |
| TextSentencer_T5 |
245-451 |
Sentence |
denotes |
In this study, we investigated the relationship between intratumoral adiponectin receptor expression and insulin resistance as well as intratumoral insulin/IGF receptor expression in breast cancer specimen. |
| T5 |
245-451 |
Sentence |
denotes |
In this study, we investigated the relationship between intratumoral adiponectin receptor expression and insulin resistance as well as intratumoral insulin/IGF receptor expression in breast cancer specimen. |
| TextSentencer_T6 |
452-460 |
Sentence |
denotes |
METHODS: |
| T6 |
452-460 |
Sentence |
denotes |
METHODS: |
| TextSentencer_T7 |
461-539 |
Sentence |
denotes |
Breast cancer tissue and fasting serum were collected from 26 female patients. |
| T7 |
461-539 |
Sentence |
denotes |
Breast cancer tissue and fasting serum were collected from 26 female patients. |
| TextSentencer_T8 |
540-724 |
Sentence |
denotes |
After microdissection of frozen samples, RNA was isolated and expression of insulin receptor, IGFR1, IGFR2, AdipoR1 and AdipoR2 was measured on mRNA level by means of real time RT-PCR. |
| T8 |
540-724 |
Sentence |
denotes |
After microdissection of frozen samples, RNA was isolated and expression of insulin receptor, IGFR1, IGFR2, AdipoR1 and AdipoR2 was measured on mRNA level by means of real time RT-PCR. |
| TextSentencer_T9 |
725-800 |
Sentence |
denotes |
Fasting insulin, glucose and c-peptide serum levels were analysed by ELISA. |
| T9 |
725-800 |
Sentence |
denotes |
Fasting insulin, glucose and c-peptide serum levels were analysed by ELISA. |
| TextSentencer_T10 |
801-856 |
Sentence |
denotes |
Insulin resistance was calculated using the HOMA model. |
| T10 |
801-856 |
Sentence |
denotes |
Insulin resistance was calculated using the HOMA model. |
| TextSentencer_T11 |
857-865 |
Sentence |
denotes |
RESULTS: |
| T11 |
857-865 |
Sentence |
denotes |
RESULTS: |
| TextSentencer_T12 |
866-962 |
Sentence |
denotes |
We were able to confirm AdipoR1 and AdipoR2 expression, respectively, in breast cancer specimen. |
| T12 |
866-962 |
Sentence |
denotes |
We were able to confirm AdipoR1 and AdipoR2 expression, respectively, in breast cancer specimen. |
| TextSentencer_T13 |
963-1120 |
Sentence |
denotes |
Actually, neither insulin serum level nor whole-body insulin resistance showed any effect on insulin/IGF or adiponectin receptor expression in breast cancer. |
| T13 |
963-1120 |
Sentence |
denotes |
Actually, neither insulin serum level nor whole-body insulin resistance showed any effect on insulin/IGF or adiponectin receptor expression in breast cancer. |
| TextSentencer_T14 |
1121-1251 |
Sentence |
denotes |
A strong positive correlation between insulin as well as IGF1 receptor and AdipoR1, but not AdipoR2, expression could be observed. |
| T14 |
1121-1251 |
Sentence |
denotes |
A strong positive correlation between insulin as well as IGF1 receptor and AdipoR1, but not AdipoR2, expression could be observed. |
| TextSentencer_T15 |
1252-1370 |
Sentence |
denotes |
Interestingly, AdipoR2 expression significantly correlated with vascular and lymphovascular invasion of breast cancer. |
| T15 |
1252-1370 |
Sentence |
denotes |
Interestingly, AdipoR2 expression significantly correlated with vascular and lymphovascular invasion of breast cancer. |
| TextSentencer_T16 |
1371-1382 |
Sentence |
denotes |
CONCLUSION: |
| T16 |
1371-1382 |
Sentence |
denotes |
CONCLUSION: |
| TextSentencer_T17 |
1383-1505 |
Sentence |
denotes |
We propose a close relationship between the intratumoral insulin signalling system and AdipoR1 but not AdipoR2 expression. |
| T17 |
1383-1505 |
Sentence |
denotes |
We propose a close relationship between the intratumoral insulin signalling system and AdipoR1 but not AdipoR2 expression. |
| TextSentencer_T18 |
1506-1662 |
Sentence |
denotes |
As AdipoR2 but not AdipoR1 expression seems to correlate with invasiveness, we assume different functions of the two adiponectin receptors in breast cancer. |
| T18 |
1506-1662 |
Sentence |
denotes |
As AdipoR2 but not AdipoR1 expression seems to correlate with invasiveness, we assume different functions of the two adiponectin receptors in breast cancer. |