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PubMed:19234785 JSONTXT 43 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-78 Sentence denotes Novel mannosidase inhibitors probe glycoprotein degradation pathways in cells.
T1 0-78 Sentence denotes Novel mannosidase inhibitors probe glycoprotein degradation pathways in cells.
TextSentencer_T2 79-206 Sentence denotes Multiple isoforms of mammalian alpha-mannosidases are active in the pathways of N-linked glycoprotein synthesis and catabolism.
T2 79-206 Sentence denotes Multiple isoforms of mammalian alpha-mannosidases are active in the pathways of N-linked glycoprotein synthesis and catabolism.
TextSentencer_T3 207-343 Sentence denotes They differ in specificity, function and location within the cell and can be selectively inhibited by imino sugar monosaccharide mimics.
T3 207-343 Sentence denotes They differ in specificity, function and location within the cell and can be selectively inhibited by imino sugar monosaccharide mimics.
TextSentencer_T4 344-508 Sentence denotes Previously, a series of structurally related novel 7-membered iminocyclitols were synthesised and found to be inhibitors of alpha-mannosidase using in vitro assays.
T4 344-508 Sentence denotes Previously, a series of structurally related novel 7-membered iminocyclitols were synthesised and found to be inhibitors of alpha-mannosidase using in vitro assays.
TextSentencer_T5 509-769 Sentence denotes The present study aimed to delineate alpha-mannosidases hydrolytic pathways in azepane inhibitor treated cells by the analysis of free oligosaccharides (FOS) as markers of endoplasmic reticulum (ER), Golgi, lysosomal and cytosolic alpha-mannosidase activities.
T5 509-769 Sentence denotes The present study aimed to delineate alpha-mannosidases hydrolytic pathways in azepane inhibitor treated cells by the analysis of free oligosaccharides (FOS) as markers of endoplasmic reticulum (ER), Golgi, lysosomal and cytosolic alpha-mannosidase activities.
TextSentencer_T6 770-863 Sentence denotes Two compounds were identified as potent and selective cytosolic alpha-mannosidase inhibitors.
T6 770-863 Sentence denotes Two compounds were identified as potent and selective cytosolic alpha-mannosidase inhibitors.
TextSentencer_T7 864-1006 Sentence denotes Two related compounds were shown to be potent inhibitors of lysosomal alpha-mannosidase with different potencies towards alpha1,6 mannosidase.
T7 864-1006 Sentence denotes Two related compounds were shown to be potent inhibitors of lysosomal alpha-mannosidase with different potencies towards alpha1,6 mannosidase.
TextSentencer_T8 1007-1147 Sentence denotes The specificities of these novel 7-membered imino sugars are related to differences in their structure and D: -mannose-like stereochemistry.
T8 1007-1147 Sentence denotes The specificities of these novel 7-membered imino sugars are related to differences in their structure and D: -mannose-like stereochemistry.
TextSentencer_T9 1148-1312 Sentence denotes Specific ER-mannosidase inhibition by kifunensine also reveals significant non-proteasomal degradation following FOS analysis and appears to be cell line dependent.
T9 1148-1312 Sentence denotes Specific ER-mannosidase inhibition by kifunensine also reveals significant non-proteasomal degradation following FOS analysis and appears to be cell line dependent.
TextSentencer_T10 1313-1434 Sentence denotes The availability of more selective inhibitors allows the pathways of N-linked oligosaccharide metabolism to be dissected.
T10 1313-1434 Sentence denotes The availability of more selective inhibitors allows the pathways of N-linked oligosaccharide metabolism to be dissected.