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PubMed:19109131 JSONTXT 10 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-124 Sentence denotes Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo.
T1 0-124 Sentence denotes Cutting edge: autoimmune disease risk variant of STAT4 confers increased sensitivity to IFN-alpha in lupus patients in vivo.
TextSentencer_T2 125-224 Sentence denotes Increased IFN-alpha signaling is a primary pathogenic factor in systemic lupus erythematosus (SLE).
T2 125-224 Sentence denotes Increased IFN-alpha signaling is a primary pathogenic factor in systemic lupus erythematosus (SLE).
TextSentencer_T3 225-392 Sentence denotes STAT4 is a transcription factor that is activated by IFN-alpha signaling, and genetic variation of STAT4 has been associated with risk of SLE and rheumatoid arthritis.
T3 225-392 Sentence denotes STAT4 is a transcription factor that is activated by IFN-alpha signaling, and genetic variation of STAT4 has been associated with risk of SLE and rheumatoid arthritis.
TextSentencer_T4 393-511 Sentence denotes We measured serum IFN-alpha activity and simultaneous IFN-alpha-induced gene expression in PBMC in a large SLE cohort.
T4 393-511 Sentence denotes We measured serum IFN-alpha activity and simultaneous IFN-alpha-induced gene expression in PBMC in a large SLE cohort.
TextSentencer_T5 512-709 Sentence denotes The risk variant of STAT4 (T allele; rs7574865) was simultaneously associated with both lower serum IFN-alpha activity and greater IFN-alpha-induced gene expression in PBMC in SLE patients in vivo.
T5 512-709 Sentence denotes The risk variant of STAT4 (T allele; rs7574865) was simultaneously associated with both lower serum IFN-alpha activity and greater IFN-alpha-induced gene expression in PBMC in SLE patients in vivo.
TextSentencer_T6 710-835 Sentence denotes Regression analyses confirmed that the risk allele of STAT4 was associated with increased sensitivity to IFN-alpha signaling.
T6 710-835 Sentence denotes Regression analyses confirmed that the risk allele of STAT4 was associated with increased sensitivity to IFN-alpha signaling.
TextSentencer_T7 836-1022 Sentence denotes The IFN regulatory factor 5 SLE risk genotype was associated with higher serum IFN-alpha activity; however, STAT4 showed dominant influence on the sensitivity of PBMC to serum IFN-alpha.
T7 836-1022 Sentence denotes The IFN regulatory factor 5 SLE risk genotype was associated with higher serum IFN-alpha activity; however, STAT4 showed dominant influence on the sensitivity of PBMC to serum IFN-alpha.
TextSentencer_T8 1023-1124 Sentence denotes These data provide biologic relevance for the risk variant of STAT4 in the IFN-alpha pathway in vivo.
T8 1023-1124 Sentence denotes These data provide biologic relevance for the risk variant of STAT4 in the IFN-alpha pathway in vivo.