| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-119 |
Sentence |
denotes |
Design and efficient synthesis of novel GM2 analogues with respect to the elucidation of the function of GM2 activator. |
| T1 |
0-119 |
Sentence |
denotes |
Design and efficient synthesis of novel GM2 analogues with respect to the elucidation of the function of GM2 activator. |
| TextSentencer_T2 |
120-448 |
Sentence |
denotes |
To elucidate the mechanism underlying the hydrolysis of the GalNAcbeta1-->4Gal linkage in ganglioside GM2 [GalNAcbeta1-->4(NeuAcalpha2-->3)Galbeta1-->4Glcbeta1-->1' Cer] by beta-hexosaminidase A (Hex A) with GM2 activator protein, we designed and synthesized two kinds of GM2 linkage analogues-6'-NeuAc-GM2 and alpha-GalNAc-GM2. |
| T2 |
120-448 |
Sentence |
denotes |
To elucidate the mechanism underlying the hydrolysis of the GalNAcbeta1-->4Gal linkage in ganglioside GM2 [GalNAcbeta1-->4(NeuAcalpha2-->3)Galbeta1-->4Glcbeta1-->1' Cer] by beta-hexosaminidase A (Hex A) with GM2 activator protein, we designed and synthesized two kinds of GM2 linkage analogues-6'-NeuAc-GM2 and alpha-GalNAc-GM2. |
| TextSentencer_T3 |
449-540 |
Sentence |
denotes |
In this paper, the efficient and systematic synthesis of these GM2 analogues was described. |
| T3 |
449-540 |
Sentence |
denotes |
In this paper, the efficient and systematic synthesis of these GM2 analogues was described. |
| TextSentencer_T4 |
541-879 |
Sentence |
denotes |
The highlight of our synthesis process is that the key intermediates, newly developed sialyllactose derivatives, were efficiently prepared in sufficient quantities; these derivatives directly served as highly reactive glycosyl acceptors and coupled with GalNTroc donors to furnish the assembly of GM2 tetrasaccharides in large quantities. |
| T4 |
541-879 |
Sentence |
denotes |
The highlight of our synthesis process is that the key intermediates, newly developed sialyllactose derivatives, were efficiently prepared in sufficient quantities; these derivatives directly served as highly reactive glycosyl acceptors and coupled with GalNTroc donors to furnish the assembly of GM2 tetrasaccharides in large quantities. |
