| Id |
Subject |
Object |
Predicate |
Lexical cue |
| TextSentencer_T1 |
0-94 |
Sentence |
denotes |
Roles of complex gangliosides in the development of experimental autoimmune encephalomyelitis. |
| T1 |
0-94 |
Sentence |
denotes |
Roles of complex gangliosides in the development of experimental autoimmune encephalomyelitis. |
| T1 |
0-94 |
Sentence |
denotes |
Roles of complex gangliosides in the development of experimental autoimmune encephalomyelitis. |
| TextSentencer_T2 |
95-374 |
Sentence |
denotes |
We induced experimental autoimmune encephalomyelitis (EAE) in GM2/GD2 synthase knockout mice (GM2/GD2-/-), which cannot synthesize complex gangliosides, such as GM1, GD1a, GD1b, GT1b, and GQ1b, to investigate the roles of complex gangliosides in the pathogenesis of this disease. |
| T2 |
95-374 |
Sentence |
denotes |
We induced experimental autoimmune encephalomyelitis (EAE) in GM2/GD2 synthase knockout mice (GM2/GD2-/-), which cannot synthesize complex gangliosides, such as GM1, GD1a, GD1b, GT1b, and GQ1b, to investigate the roles of complex gangliosides in the pathogenesis of this disease. |
| T2 |
95-374 |
Sentence |
denotes |
We induced experimental autoimmune encephalomyelitis (EAE) in GM2/GD2 synthase knockout mice (GM2/GD2-/-), which cannot synthesize complex gangliosides, such as GM1, GD1a, GD1b, GT1b, and GQ1b, to investigate the roles of complex gangliosides in the pathogenesis of this disease. |
| TextSentencer_T3 |
375-441 |
Sentence |
denotes |
We used myelin-oligodendrocyte glycoprotein (MOG) as an immunogen. |
| T3 |
375-441 |
Sentence |
denotes |
We used myelin-oligodendrocyte glycoprotein (MOG) as an immunogen. |
| T3 |
375-441 |
Sentence |
denotes |
We used myelin-oligodendrocyte glycoprotein (MOG) as an immunogen. |
| TextSentencer_T4 |
442-619 |
Sentence |
denotes |
In active immunization EAE, the severity of clinical score was not different but the disease onset was significantly delayed in GM2/GD2-/- compared with those in wild-type mice. |
| T4 |
442-619 |
Sentence |
denotes |
In active immunization EAE, the severity of clinical score was not different but the disease onset was significantly delayed in GM2/GD2-/- compared with those in wild-type mice. |
| T4 |
442-619 |
Sentence |
denotes |
In active immunization EAE, the severity of clinical score was not different but the disease onset was significantly delayed in GM2/GD2-/- compared with those in wild-type mice. |
| TextSentencer_T5 |
620-778 |
Sentence |
denotes |
When we transferred MOG-reactive T cells from GM2/GD2-/- or wild-type mice to wild-type mice, no significant differences were observed between the two groups. |
| T5 |
620-778 |
Sentence |
denotes |
When we transferred MOG-reactive T cells from GM2/GD2-/- or wild-type mice to wild-type mice, no significant differences were observed between the two groups. |
| T5 |
620-778 |
Sentence |
denotes |
When we transferred MOG-reactive T cells from GM2/GD2-/- or wild-type mice to wild-type mice, no significant differences were observed between the two groups. |
| TextSentencer_T6 |
779-937 |
Sentence |
denotes |
In contrast, when we transferred MOG-reactive T cells from wild-type mice to GM2/GD2-/- or to wild-type mice, the onset of EAE in GM2/GD2-/- mice was delayed. |
| T6 |
779-937 |
Sentence |
denotes |
In contrast, when we transferred MOG-reactive T cells from wild-type mice to GM2/GD2-/- or to wild-type mice, the onset of EAE in GM2/GD2-/- mice was delayed. |
| T6 |
779-937 |
Sentence |
denotes |
In contrast, when we transferred MOG-reactive T cells from wild-type mice to GM2/GD2-/- or to wild-type mice, the onset of EAE in GM2/GD2-/- mice was delayed. |
| TextSentencer_T7 |
938-1163 |
Sentence |
denotes |
The recall response of MOG-specific T cells, the function of antigen presenting cells, or the expression of several adhesion molecules in the endothelium were not significantly different between GM2/GD2-/- and wild-type mice. |
| T7 |
938-1163 |
Sentence |
denotes |
The recall response of MOG-specific T cells, the function of antigen presenting cells, or the expression of several adhesion molecules in the endothelium were not significantly different between GM2/GD2-/- and wild-type mice. |
| T7 |
938-1163 |
Sentence |
denotes |
The recall response of MOG-specific T cells, the function of antigen presenting cells, or the expression of several adhesion molecules in the endothelium were not significantly different between GM2/GD2-/- and wild-type mice. |
| TextSentencer_T8 |
1164-1429 |
Sentence |
denotes |
On the other hand, quantitative analysis of cellular infiltration in the central nervous system (CNS) on day 9 of active immunization EAE showed that the CD4+ cell number in the CNS isolated from GM2/GD2-/- mice was significantly less than that from wild-type mice. |
| T8 |
1164-1429 |
Sentence |
denotes |
On the other hand, quantitative analysis of cellular infiltration in the central nervous system (CNS) on day 9 of active immunization EAE showed that the CD4+ cell number in the CNS isolated from GM2/GD2-/- mice was significantly less than that from wild-type mice. |
| T8 |
1164-1429 |
Sentence |
denotes |
On the other hand, quantitative analysis of cellular infiltration in the central nervous system (CNS) on day 9 of active immunization EAE showed that the CD4+ cell number in the CNS isolated from GM2/GD2-/- mice was significantly less than that from wild-type mice. |
| TextSentencer_T9 |
1430-1565 |
Sentence |
denotes |
It indicated that the delayed onset of EAE in GM2/GD2-/- mice was due to the delay of the migration of pathogenic T cells into the CNS. |
| T9 |
1430-1565 |
Sentence |
denotes |
It indicated that the delayed onset of EAE in GM2/GD2-/- mice was due to the delay of the migration of pathogenic T cells into the CNS. |
| T9 |
1430-1565 |
Sentence |
denotes |
It indicated that the delayed onset of EAE in GM2/GD2-/- mice was due to the delay of the migration of pathogenic T cells into the CNS. |
| TextSentencer_T10 |
1566-1691 |
Sentence |
denotes |
Thus, the complex gangliosides may be involved in the T cell-endothelial cell interaction in the pathogenetic process of EAE. |
| T10 |
1566-1691 |
Sentence |
denotes |
Thus, the complex gangliosides may be involved in the T cell-endothelial cell interaction in the pathogenetic process of EAE. |
| T10 |
1566-1691 |
Sentence |
denotes |
Thus, the complex gangliosides may be involved in the T cell-endothelial cell interaction in the pathogenetic process of EAE. |