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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-95 Sentence denotes Transcriptional regulation of the fucosyltransferase VI gene in hepatocellular carcinoma cells.
T1 0-95 Sentence denotes Transcriptional regulation of the fucosyltransferase VI gene in hepatocellular carcinoma cells.
TextSentencer_T2 96-228 Sentence denotes The alpha1,3-fucosyltransferase VI (FUT VI) protein is a key enzyme for synthesis of sialyl Lewis X and Lewis X in epithelial cells.
T2 96-228 Sentence denotes The alpha1,3-fucosyltransferase VI (FUT VI) protein is a key enzyme for synthesis of sialyl Lewis X and Lewis X in epithelial cells.
TextSentencer_T3 229-323 Sentence denotes Despite its importance, how FUT VI expression is regulated has not previously been elucidated.
T3 229-323 Sentence denotes Despite its importance, how FUT VI expression is regulated has not previously been elucidated.
TextSentencer_T4 324-436 Sentence denotes In this work, we examined transcriptional regulation of the FUT VI gene in hepatocellular carcinoma HepG2 cells.
T4 324-436 Sentence denotes In this work, we examined transcriptional regulation of the FUT VI gene in hepatocellular carcinoma HepG2 cells.
TextSentencer_T5 437-665 Sentence denotes 5'-Rapid amplification of cDNA ends analysis revealed transcription start sites of FUT VI in HepG2 cells at +65 and +278 nucleotides (nt) downstream of the position registered in the Data Base of Human Transcription Start Sites.
T5 437-665 Sentence denotes 5'-Rapid amplification of cDNA ends analysis revealed transcription start sites of FUT VI in HepG2 cells at +65 and +278 nucleotides (nt) downstream of the position registered in the Data Base of Human Transcription Start Sites.
TextSentencer_T6 666-762 Sentence denotes We determined promoter regions for FUT VI in HepG2 cells using a luciferase reporter gene assay.
T6 666-762 Sentence denotes We determined promoter regions for FUT VI in HepG2 cells using a luciferase reporter gene assay.
TextSentencer_T7 763-924 Sentence denotes The promoter activities of constructs located 5'-upstream of the transcription start site decreased when the -186 to -156 and -56 to -19 nt regions were deleted.
T7 763-924 Sentence denotes The promoter activities of constructs located 5'-upstream of the transcription start site decreased when the -186 to -156 and -56 to -19 nt regions were deleted.
TextSentencer_T8 925-1142 Sentence denotes Site-directed mutagenesis of these regions revealed that two hepatocyte nuclear factor-4 alpha (HNF-4 alpha) and one octamer binding transcription factor-1 (Oct-1) binding sites are essential for FUT VI transcription.
T8 925-1142 Sentence denotes Site-directed mutagenesis of these regions revealed that two hepatocyte nuclear factor-4 alpha (HNF-4 alpha) and one octamer binding transcription factor-1 (Oct-1) binding sites are essential for FUT VI transcription.
TextSentencer_T9 1143-1290 Sentence denotes Furthermore, transient over-expression of HNF-4 alpha but not Oct-1 enhanced both FUT VI promoter activities and FUT VI mRNA levels in HuH-7 cells.
T9 1143-1290 Sentence denotes Furthermore, transient over-expression of HNF-4 alpha but not Oct-1 enhanced both FUT VI promoter activities and FUT VI mRNA levels in HuH-7 cells.
TextSentencer_T10 1291-1456 Sentence denotes These results suggest that two defined regions in the 5'-flanking region of the FUT VI transcription start site are critical for FUT VI transcription in HepG2 cells.
T10 1291-1456 Sentence denotes These results suggest that two defined regions in the 5'-flanking region of the FUT VI transcription start site are critical for FUT VI transcription in HepG2 cells.