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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-121 Sentence denotes Sialyl cholesterol is translocated into cell nuclei and it promotes neurite outgrowth in a mouse neuroblastoma cell line.
T1 0-121 Sentence denotes Sialyl cholesterol is translocated into cell nuclei and it promotes neurite outgrowth in a mouse neuroblastoma cell line.
T1 0-121 Sentence denotes Sialyl cholesterol is translocated into cell nuclei and it promotes neurite outgrowth in a mouse neuroblastoma cell line.
TextSentencer_T2 122-347 Sentence denotes To determine the mechanisms of the neuritogenesis induced by synthetic sialyl cholesterol (SC) in a mouse neuroblastoma cell line, Neuro2a, the biochemical fate of SC and ganglioside GM1 (IV3NeuAc-GgOse4Cer) was investigated.
T2 122-347 Sentence denotes To determine the mechanisms of the neuritogenesis induced by synthetic sialyl cholesterol (SC) in a mouse neuroblastoma cell line, Neuro2a, the biochemical fate of SC and ganglioside GM1 (IV3NeuAc-GgOse4Cer) was investigated.
T2 122-347 Sentence denotes To determine the mechanisms of the neuritogenesis induced by synthetic sialyl cholesterol (SC) in a mouse neuroblastoma cell line, Neuro2a, the biochemical fate of SC and ganglioside GM1 (IV3NeuAc-GgOse4Cer) was investigated.
TextSentencer_T3 348-438 Sentence denotes The kinetics of incorporation of SC and GM1 into cells for the two compounds were similar.
T3 348-438 Sentence denotes The kinetics of incorporation of SC and GM1 into cells for the two compounds were similar.
T3 348-438 Sentence denotes The kinetics of incorporation of SC and GM1 into cells for the two compounds were similar.
TextSentencer_T4 439-612 Sentence denotes SC was not degraded nor modified for at least 24 h after the incorporation, indicating that SC itself and not its metabolites were responsible for the neuritogenic activity.
T4 439-612 Sentence denotes SC was not degraded nor modified for at least 24 h after the incorporation, indicating that SC itself and not its metabolites were responsible for the neuritogenic activity.
T4 439-612 Sentence denotes SC was not degraded nor modified for at least 24 h after the incorporation, indicating that SC itself and not its metabolites were responsible for the neuritogenic activity.
TextSentencer_T5 613-800 Sentence denotes Cell fractionation experiments showed that approximately 40% of the incorporated SC was localized in the nucleus, 25% in the plasma membrane fractions, and 11-14% in the granule fraction.
T5 613-800 Sentence denotes Cell fractionation experiments showed that approximately 40% of the incorporated SC was localized in the nucleus, 25% in the plasma membrane fractions, and 11-14% in the granule fraction.
T5 613-800 Sentence denotes Cell fractionation experiments showed that approximately 40% of the incorporated SC was localized in the nucleus, 25% in the plasma membrane fractions, and 11-14% in the granule fraction.
TextSentencer_T6 801-850 Sentence denotes This distribution was different from that of GM1.
T6 801-850 Sentence denotes This distribution was different from that of GM1.
T6 801-850 Sentence denotes This distribution was different from that of GM1.
TextSentencer_T7 851-988 Sentence denotes The nuclear SC was found to affect de novo RNA synthesis, indicating its biological effect may be mediated at the level of transcription.
T7 851-988 Sentence denotes The nuclear SC was found to affect de novo RNA synthesis, indicating its biological effect may be mediated at the level of transcription.
T7 851-988 Sentence denotes The nuclear SC was found to affect de novo RNA synthesis, indicating its biological effect may be mediated at the level of transcription.
TextSentencer_T8 989-1115 Sentence denotes SC also increased the rates of both Ca2+ influx and efflux, although the intracellular level of total Ca2+ remained unchanged.
T8 989-1115 Sentence denotes SC also increased the rates of both Ca2+ influx and efflux, although the intracellular level of total Ca2+ remained unchanged.
T8 989-1115 Sentence denotes SC also increased the rates of both Ca2+ influx and efflux, although the intracellular level of total Ca2+ remained unchanged.
TextSentencer_T9 1116-1299 Sentence denotes Levels of inositol 1,4,5-triphosphate (IP3) also remained unchanged and the SC dependent neuritogenesis was not inhibited by an excess amount of W-7, an inhibitor of Ca2+/CaM kinases.
T9 1116-1299 Sentence denotes Levels of inositol 1,4,5-triphosphate (IP3) also remained unchanged and the SC dependent neuritogenesis was not inhibited by an excess amount of W-7, an inhibitor of Ca2+/CaM kinases.
T9 1116-1299 Sentence denotes Levels of inositol 1,4,5-triphosphate (IP3) also remained unchanged and the SC dependent neuritogenesis was not inhibited by an excess amount of W-7, an inhibitor of Ca2+/CaM kinases.
TextSentencer_T10 1300-1441 Sentence denotes These results again accord with the suggestion that SC and GM1 do not utilize Ca2+, IP3 or Ca2+/CaM as a second messenger for neuritogenesis.
T10 1300-1441 Sentence denotes These results again accord with the suggestion that SC and GM1 do not utilize Ca2+, IP3 or Ca2+/CaM as a second messenger for neuritogenesis.
T10 1300-1441 Sentence denotes These results again accord with the suggestion that SC and GM1 do not utilize Ca2+, IP3 or Ca2+/CaM as a second messenger for neuritogenesis.
TextSentencer_T11 1442-1540 Sentence denotes Rather it appears very likely that the nuclear localized SC may play a key role in neuritogenesis.
T11 1442-1540 Sentence denotes Rather it appears very likely that the nuclear localized SC may play a key role in neuritogenesis.
T11 1442-1540 Sentence denotes Rather it appears very likely that the nuclear localized SC may play a key role in neuritogenesis.