> top > projects > sentences > docs > PubMed:18184719 > annotations
sentences Home  

PubMed:18184719 JSONTXT 82 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-158 Sentence denotes Embryonic stem cells deficient in I beta1,6-N-acetylglucosaminyltransferase exhibit reduced expression of embryoglycan and the loss of a Lewis X antigen, 4C9.
T1 0-158 Sentence denotes Embryonic stem cells deficient in I beta1,6-N-acetylglucosaminyltransferase exhibit reduced expression of embryoglycan and the loss of a Lewis X antigen, 4C9.
TextSentencer_T2 159-395 Sentence denotes Embryoglycan is a class of branched high-molecular-weight poly-N-acetyllactosamines characteristically expressed in early embryonic cells and has been shown to be involved in the intercellular adhesion of early embryonic cells in vitro.
T2 159-395 Sentence denotes Embryoglycan is a class of branched high-molecular-weight poly-N-acetyllactosamines characteristically expressed in early embryonic cells and has been shown to be involved in the intercellular adhesion of early embryonic cells in vitro.
TextSentencer_T3 396-517 Sentence denotes Branching of poly-N-acetyllactosamine chains is performed by beta1,6-N-acetylglucosaminylation of the galactosyl residue.
T3 396-517 Sentence denotes Branching of poly-N-acetyllactosamine chains is performed by beta1,6-N-acetylglucosaminylation of the galactosyl residue.
TextSentencer_T4 518-740 Sentence denotes We previously knocked out the gene encoding I beta1, 6-N-acetylglucosaminyltransferase (IGnT), and the resultant deficient mice were born without any abnormality, although the mice exhibited various deficits in later life.
T4 518-740 Sentence denotes We previously knocked out the gene encoding I beta1, 6-N-acetylglucosaminyltransferase (IGnT), and the resultant deficient mice were born without any abnormality, although the mice exhibited various deficits in later life.
TextSentencer_T5 741-837 Sentence denotes In the present investigation, we produced embryonic stem (ES) cells from IGnT-deficient embryos.
T5 741-837 Sentence denotes In the present investigation, we produced embryonic stem (ES) cells from IGnT-deficient embryos.
TextSentencer_T6 838-915 Sentence denotes The mutant ES cells exhibited a reduced capability in embryoglycan synthesis.
T6 838-915 Sentence denotes The mutant ES cells exhibited a reduced capability in embryoglycan synthesis.
TextSentencer_T7 916-1022 Sentence denotes Thus, IGnT is a major enzyme involved in the branching of poly-N-acetyllactosamine chains in embryoglycan.
T7 916-1022 Sentence denotes Thus, IGnT is a major enzyme involved in the branching of poly-N-acetyllactosamine chains in embryoglycan.
TextSentencer_T8 1023-1251 Sentence denotes Since ES cells are equivalent to multipotential cells of the embryonic ectoderm in early postimplantation embryos, this result indicates that an abundance of embryoglycan in these cells is not essential for normal embryogenesis.
T8 1023-1251 Sentence denotes Since ES cells are equivalent to multipotential cells of the embryonic ectoderm in early postimplantation embryos, this result indicates that an abundance of embryoglycan in these cells is not essential for normal embryogenesis.
TextSentencer_T9 1252-1444 Sentence denotes The IGnT-deficient ES cells continued to express SSEA-1, but lacked the expression of 4C9 antigen, although the epitope of 4C9 antigen was confirmed to be Lewis X by a transfection experiment.
T9 1252-1444 Sentence denotes The IGnT-deficient ES cells continued to express SSEA-1, but lacked the expression of 4C9 antigen, although the epitope of 4C9 antigen was confirmed to be Lewis X by a transfection experiment.
TextSentencer_T10 1445-1649 Sentence denotes The result establishes the distinct nature of 4C9 antigenicity, which requires either Lewis X epitope on I-branch or clustering of Lewis X epitope, best accomplished by poly-N-acetyllactosamine branching.
T10 1445-1649 Sentence denotes The result establishes the distinct nature of 4C9 antigenicity, which requires either Lewis X epitope on I-branch or clustering of Lewis X epitope, best accomplished by poly-N-acetyllactosamine branching.
TextSentencer_T11 1650-1716 Sentence denotes Alpha6-integrin was newly identified as a carrier of embryoglycan.
T11 1650-1716 Sentence denotes Alpha6-integrin was newly identified as a carrier of embryoglycan.
TextSentencer_T12 1717-1974 Sentence denotes The IGnT-deficient ES cells adhered to dishes coated with laminin, which is a ligand for alpha6-integrin, significantly less than wild-type ES cells, raising the possibility that embryoglycan in ES cells enhances alpha6-integrin-dependent adhesion in vitro.
T12 1717-1974 Sentence denotes The IGnT-deficient ES cells adhered to dishes coated with laminin, which is a ligand for alpha6-integrin, significantly less than wild-type ES cells, raising the possibility that embryoglycan in ES cells enhances alpha6-integrin-dependent adhesion in vitro.