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PubMed:17623665 JSONTXT 41 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-115 Sentence denotes A strategic protein in cytochrome c maturation: three-dimensional structure of CcmH and binding to apocytochrome c.
T1 0-115 Sentence denotes A strategic protein in cytochrome c maturation: three-dimensional structure of CcmH and binding to apocytochrome c.
TextSentencer_T2 116-299 Sentence denotes CcmH (cytochromes c maturation protein H) is an essential component of the assembly line necessary for the maturation of c-type cytochromes in the periplasm of Gram-negative bacteria.
T2 116-299 Sentence denotes CcmH (cytochromes c maturation protein H) is an essential component of the assembly line necessary for the maturation of c-type cytochromes in the periplasm of Gram-negative bacteria.
TextSentencer_T3 300-495 Sentence denotes The protein is a membrane-anchored thiol-oxidoreductase that has been hypothesized to be involved in the recognition and reduction of apocytochrome c, a prerequisite for covalent heme attachment.
T3 300-495 Sentence denotes The protein is a membrane-anchored thiol-oxidoreductase that has been hypothesized to be involved in the recognition and reduction of apocytochrome c, a prerequisite for covalent heme attachment.
TextSentencer_T4 496-648 Sentence denotes Here, we present the 1.7A crystal structure of the soluble periplasmic domain of CcmH from the opportunistic pathogen Pseudomonas aeruginosa (Pa-CcmH*).
T4 496-648 Sentence denotes Here, we present the 1.7A crystal structure of the soluble periplasmic domain of CcmH from the opportunistic pathogen Pseudomonas aeruginosa (Pa-CcmH*).
TextSentencer_T5 649-783 Sentence denotes The protein contains a three-helix bundle, i.e. a fold that is different from that of all other thiol-oxidoreductases reported so far.
T5 649-783 Sentence denotes The protein contains a three-helix bundle, i.e. a fold that is different from that of all other thiol-oxidoreductases reported so far.
TextSentencer_T6 784-966 Sentence denotes The catalytic Cys residues of the conserved LRCXXC motif (Cys(25) and Cys(28)), located in a long loop connecting the first two helices, form a disulfide bond in the oxidized enzyme.
T6 784-966 Sentence denotes The catalytic Cys residues of the conserved LRCXXC motif (Cys(25) and Cys(28)), located in a long loop connecting the first two helices, form a disulfide bond in the oxidized enzyme.
TextSentencer_T7 967-1153 Sentence denotes We have determined the pK(a) values of these 2 Cys residues of Pa-CcmH* (both >8) and propose a possible mechanistic role for a conserved Ser(36) and a water molecule in the active site.
T7 967-1153 Sentence denotes We have determined the pK(a) values of these 2 Cys residues of Pa-CcmH* (both >8) and propose a possible mechanistic role for a conserved Ser(36) and a water molecule in the active site.
TextSentencer_T8 1154-1465 Sentence denotes The interaction between Pa-CcmH* and Pa-apocyt c(551) (where cyt c(551) represents cytochrome c(551)) was characterized in vitro following the binding kinetics by stopped-flow using a Trp-containing fluorescent variant of Pa-CcmH* and a dansylated peptide, mimicking the apocytochrome c(551) heme binding motif.
T8 1154-1465 Sentence denotes The interaction between Pa-CcmH* and Pa-apocyt c(551) (where cyt c(551) represents cytochrome c(551)) was characterized in vitro following the binding kinetics by stopped-flow using a Trp-containing fluorescent variant of Pa-CcmH* and a dansylated peptide, mimicking the apocytochrome c(551) heme binding motif.
TextSentencer_T9 1466-1676 Sentence denotes The kinetic results show that the protein has a moderate affinity to its apocyt substrate, consistent with the role of Pa-CcmH as an intermediate component of the assembly line for c-type cytochrome biogenesis.
T9 1466-1676 Sentence denotes The kinetic results show that the protein has a moderate affinity to its apocyt substrate, consistent with the role of Pa-CcmH as an intermediate component of the assembly line for c-type cytochrome biogenesis.