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PubMed:17573341 JSONTXT 21 Projects

Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
T1 0-134 Sentence denotes Genome-scale reconstruction of metabolic network in Bacillus subtilis based on high-throughput phenotyping and gene essentiality data.
T1 0-134 Sentence denotes Genome-scale reconstruction of metabolic network in Bacillus subtilis based on high-throughput phenotyping and gene essentiality data.
T2 135-380 Sentence denotes In this report, a genome-scale reconstruction of Bacillus subtilis metabolism and its iterative development based on the combination of genomic, biochemical, and physiological information and high-throughput phenotyping experiments is presented.
T2 135-380 Sentence denotes In this report, a genome-scale reconstruction of Bacillus subtilis metabolism and its iterative development based on the combination of genomic, biochemical, and physiological information and high-throughput phenotyping experiments is presented.
T3 381-492 Sentence denotes The initial reconstruction was converted into an in silico model and expanded in a four-step iterative fashion.
T3 381-492 Sentence denotes The initial reconstruction was converted into an in silico model and expanded in a four-step iterative fashion.
T4 493-634 Sentence denotes First, network gap analysis was used to identify 48 missing reactions that are needed for growth but were not found in the genome annotation.
T4 493-634 Sentence denotes First, network gap analysis was used to identify 48 missing reactions that are needed for growth but were not found in the genome annotation.
T5 635-857 Sentence denotes Second, the computed growth rates under aerobic conditions were compared with high-throughput phenotypic screen data, and the initial in silico model could predict the outcomes qualitatively in 140 of 271 cases considered.
T5 635-857 Sentence denotes Second, the computed growth rates under aerobic conditions were compared with high-throughput phenotypic screen data, and the initial in silico model could predict the outcomes qualitatively in 140 of 271 cases considered.
T6 858-1022 Sentence denotes Detailed analysis of the incorrect predictions resulted in the addition of 75 reactions to the initial reconstruction, and 200 of 271 cases were correctly computed.
T6 858-1022 Sentence denotes Detailed analysis of the incorrect predictions resulted in the addition of 75 reactions to the initial reconstruction, and 200 of 271 cases were correctly computed.
T7 1023-1188 Sentence denotes Third, in silico computations of the growth phenotypes of knock-out strains were found to be consistent with experimental observations in 720 of 766 cases evaluated.
T7 1023-1188 Sentence denotes Third, in silico computations of the growth phenotypes of knock-out strains were found to be consistent with experimental observations in 720 of 766 cases evaluated.
T8 1189-1459 Sentence denotes Fourth, the integrated analysis of the large-scale substrate utilization and gene essentiality data with the genome-scale metabolic model revealed the requirement of 80 specific enzymes (transport, 53; intracellular reactions, 27) that were not in the genome annotation.
T8 1189-1459 Sentence denotes Fourth, the integrated analysis of the large-scale substrate utilization and gene essentiality data with the genome-scale metabolic model revealed the requirement of 80 specific enzymes (transport, 53; intracellular reactions, 27) that were not in the genome annotation.
T9 1460-1591 Sentence denotes Subsequent sequence analysis resulted in the identification of genes that could be putatively assigned to 13 intracellular enzymes.
T9 1460-1591 Sentence denotes Subsequent sequence analysis resulted in the identification of genes that could be putatively assigned to 13 intracellular enzymes.
T10 1592-1717 Sentence denotes The final reconstruction accounted for 844 open reading frames and consisted of 1020 metabolic reactions and 988 metabolites.
T10 1592-1717 Sentence denotes The final reconstruction accounted for 844 open reading frames and consisted of 1020 metabolic reactions and 988 metabolites.
T11 1718-1848 Sentence denotes Hence, the in silico model can be used to obtain experimentally verifiable hypothesis on the metabolic functions of various genes.
T11 1718-1848 Sentence denotes Hence, the in silico model can be used to obtain experimentally verifiable hypothesis on the metabolic functions of various genes.