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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-49 Sentence denotes Clonal origin of metastatic testicular teratomas.
T1 0-49 Sentence denotes Clonal origin of metastatic testicular teratomas.
TextSentencer_T2 50-58 Sentence denotes PURPOSE:
T2 50-58 Sentence denotes PURPOSE:
TextSentencer_T3 59-200 Sentence denotes Testicular teratomas in adult patients are histologically diverse tumors that frequently coexist with other germ cell tumor (GCT) components.
T3 59-200 Sentence denotes Testicular teratomas in adult patients are histologically diverse tumors that frequently coexist with other germ cell tumor (GCT) components.
TextSentencer_T4 201-348 Sentence denotes These mixed GCTs often metastasize to retroperitoneal lymph nodes where multiple GCT elements are frequently present in the same metastatic lesion.
T4 201-348 Sentence denotes These mixed GCTs often metastasize to retroperitoneal lymph nodes where multiple GCT elements are frequently present in the same metastatic lesion.
TextSentencer_T5 349-525 Sentence denotes Neither the genetic relationships among the different components in metastatic lesions nor the relationships between primary and metastatic GCT components have been elucidated.
T5 349-525 Sentence denotes Neither the genetic relationships among the different components in metastatic lesions nor the relationships between primary and metastatic GCT components have been elucidated.
TextSentencer_T6 526-546 Sentence denotes EXPERIMENTAL DESIGN:
T6 526-546 Sentence denotes EXPERIMENTAL DESIGN:
TextSentencer_T7 547-677 Sentence denotes We examined metastases from 31 patients who underwent primary retroperitoneal lymph node dissection for metastatic testicular GCT.
T7 547-677 Sentence denotes We examined metastases from 31 patients who underwent primary retroperitoneal lymph node dissection for metastatic testicular GCT.
TextSentencer_T8 678-760 Sentence denotes All patients had metastatic mature teratoma with one or more other GCT components.
T8 678-760 Sentence denotes All patients had metastatic mature teratoma with one or more other GCT components.
TextSentencer_T9 761-868 Sentence denotes This study included a total of 72 metastatic GCT components and 16 primary GCT components from 31 patients.
T9 761-868 Sentence denotes This study included a total of 72 metastatic GCT components and 16 primary GCT components from 31 patients.
TextSentencer_T10 869-1015 Sentence denotes Genomic DNA samples from each component were prepared from formalin-fixed, paraffin-embedded tissue sections using laser-assisted microdissection.
T10 869-1015 Sentence denotes Genomic DNA samples from each component were prepared from formalin-fixed, paraffin-embedded tissue sections using laser-assisted microdissection.
TextSentencer_T11 1016-1254 Sentence denotes Loss of heterozygosity (LOH) assays for seven microsatellite polymorphic markers on chromosomes 1p36 (D1S1646), 9p21 (D9S171 and IFNA), 9q21 (D9S303), 13q22-q31 (D13S317), 18q22 (D18S543), and 18q21 (D18S60) were done to assess clonality.
T11 1016-1254 Sentence denotes Loss of heterozygosity (LOH) assays for seven microsatellite polymorphic markers on chromosomes 1p36 (D1S1646), 9p21 (D9S171 and IFNA), 9q21 (D9S303), 13q22-q31 (D13S317), 18q22 (D18S543), and 18q21 (D18S60) were done to assess clonality.
TextSentencer_T12 1255-1263 Sentence denotes RESULTS:
T12 1255-1263 Sentence denotes RESULTS:
TextSentencer_T13 1264-1363 Sentence denotes Twenty-nine of 31 (94%) cases showed allelic loss in one or more components of the metastatic GCTs.
T13 1264-1363 Sentence denotes Twenty-nine of 31 (94%) cases showed allelic loss in one or more components of the metastatic GCTs.
TextSentencer_T14 1364-1488 Sentence denotes Twenty-nine of 31 mature teratomas showed allelic loss in at least one of seven microsatellite polymorphic markers analyzed.
T14 1364-1488 Sentence denotes Twenty-nine of 31 mature teratomas showed allelic loss in at least one of seven microsatellite polymorphic markers analyzed.
TextSentencer_T15 1489-1771 Sentence denotes The frequency of allelic loss in informative cases of metastatic mature teratoma was 27% (8 of 30) with D1S1646, 34% (10 of 29) with D9S171, 37% (10 of 27) with IFNA, 27% (8 of 30) with D9S303, 46% (13 of 28) with D13S317, 26% (7 of 27) with D18S543, and 36% (10 of 28) with D18S60.
T15 1489-1771 Sentence denotes The frequency of allelic loss in informative cases of metastatic mature teratoma was 27% (8 of 30) with D1S1646, 34% (10 of 29) with D9S171, 37% (10 of 27) with IFNA, 27% (8 of 30) with D9S303, 46% (13 of 28) with D13S317, 26% (7 of 27) with D18S543, and 36% (10 of 28) with D18S60.
TextSentencer_T16 1772-1969 Sentence denotes Completely concordant allelic loss patterns between the mature teratoma and all of the other metastatic GCT components were seen in 26 of 29 cases in which the mature teratoma component showed LOH.
T16 1772-1969 Sentence denotes Completely concordant allelic loss patterns between the mature teratoma and all of the other metastatic GCT components were seen in 26 of 29 cases in which the mature teratoma component showed LOH.
TextSentencer_T17 1970-2048 Sentence denotes Nearly identical allelic loss patterns were seen in the three remaining cases.
T17 1970-2048 Sentence denotes Nearly identical allelic loss patterns were seen in the three remaining cases.
TextSentencer_T18 2049-2184 Sentence denotes In six cases analyzed, LOH patterns of each metastatic component were compared with each GCT component of the primary testicular tumor.
T18 2049-2184 Sentence denotes In six cases analyzed, LOH patterns of each metastatic component were compared with each GCT component of the primary testicular tumor.
TextSentencer_T19 2185-2285 Sentence denotes In all six cases, each primary and metastatic component showed an identical pattern of allelic loss.
T19 2185-2285 Sentence denotes In all six cases, each primary and metastatic component showed an identical pattern of allelic loss.
TextSentencer_T20 2286-2297 Sentence denotes CONCLUSION:
T20 2286-2297 Sentence denotes CONCLUSION:
TextSentencer_T21 2298-2468 Sentence denotes Our data support the common clonal origin of metastatic mature teratomas with other components of metastatic testicular GCTs and with each component of the primary tumor.
T21 2298-2468 Sentence denotes Our data support the common clonal origin of metastatic mature teratomas with other components of metastatic testicular GCTs and with each component of the primary tumor.