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PubMed:16691501 JSONTXT 59 Projects

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Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-90 Sentence denotes Apoptosis of human breast carcinoma cells in the presence of cis-platin and L-/D-PPMP: IV.
T1 0-90 Sentence denotes Apoptosis of human breast carcinoma cells in the presence of cis-platin and L-/D-PPMP: IV.
TextSentencer_T2 91-142 Sentence denotes Modulation of replication complexes and glycolipid:
T2 91-142 Sentence denotes Modulation of replication complexes and glycolipid:
TextSentencer_T3 143-164 Sentence denotes Glycosyltransferases.
T3 143-164 Sentence denotes Glycosyltransferases.
TextSentencer_T4 165-391 Sentence denotes Apoptosis of human breast carcinoma cells (SKBR-3, MCF-7, and MDA-468) has been observed after treatment of these cells with anti-cancer drug cis-platin and glycosphingolipid biosynthesis inhibitor L- and D-PPMP, respectively.
T4 165-391 Sentence denotes Apoptosis of human breast carcinoma cells (SKBR-3, MCF-7, and MDA-468) has been observed after treatment of these cells with anti-cancer drug cis-platin and glycosphingolipid biosynthesis inhibitor L- and D-PPMP, respectively.
TextSentencer_T5 392-662 Sentence denotes These drugs initiated apoptosis in a dose-dependent manner as measured by phenotypic morphological changes, by binding of a fluorescent phophatidyl serine-specific dye (PSS-380) onto the outer leaflet of the cell membranes, and by activation of caspases, -3, -8, and -9.
T5 392-662 Sentence denotes These drugs initiated apoptosis in a dose-dependent manner as measured by phenotypic morphological changes, by binding of a fluorescent phophatidyl serine-specific dye (PSS-380) onto the outer leaflet of the cell membranes, and by activation of caspases, -3, -8, and -9.
TextSentencer_T6 663-794 Sentence denotes It was observed that in two hours very little apoptotic process had started but predominant biochemical changes occurred after 6 h.
T6 663-794 Sentence denotes It was observed that in two hours very little apoptotic process had started but predominant biochemical changes occurred after 6 h.
TextSentencer_T7 795-852 Sentence denotes DNA degradation started after 24 hours of drug treatment.
T7 795-852 Sentence denotes DNA degradation started after 24 hours of drug treatment.
TextSentencer_T8 853-965 Sentence denotes However, very little is known about the stability of the ';Replication Complexes'' during the apoptotic process.
T8 853-965 Sentence denotes However, very little is known about the stability of the ';Replication Complexes'' during the apoptotic process.
TextSentencer_T9 966-1100 Sentence denotes DNA helicases are motor proteins that catalyze the melting of genomic DNA during its replication, repair, and recombination processes.
T9 966-1100 Sentence denotes DNA helicases are motor proteins that catalyze the melting of genomic DNA during its replication, repair, and recombination processes.
TextSentencer_T10 1101-1275 Sentence denotes Previously, DNA helicase-III was characterized as a component of the replication complexes isolated from embryonic chicken brains as well as breast and colon carcinoma cells.
T10 1101-1275 Sentence denotes Previously, DNA helicase-III was characterized as a component of the replication complexes isolated from embryonic chicken brains as well as breast and colon carcinoma cells.
TextSentencer_T11 1276-1524 Sentence denotes Helicase activities were measured by a novel method (ROME assay), and DNA polymerase-alpha activities were determined by regular chain extension of the nicked ACT-DNA, by determining values obtained from +/- aphidicolin-treated incubation mixtures.
T11 1276-1524 Sentence denotes Helicase activities were measured by a novel method (ROME assay), and DNA polymerase-alpha activities were determined by regular chain extension of the nicked ACT-DNA, by determining values obtained from +/- aphidicolin-treated incubation mixtures.
TextSentencer_T12 1525-1662 Sentence denotes In all three breast carcinoma cell lines, a common trend was observed: a decrease of activities of DNA polymerase-alpha and Helicase III.
T12 1525-1662 Sentence denotes In all three breast carcinoma cell lines, a common trend was observed: a decrease of activities of DNA polymerase-alpha and Helicase III.
TextSentencer_T13 1663-1928 Sentence denotes A sharp decrease of activities of the glycolipid sialyltransferases: SAT-2 (CMP-NeuAc; GD3 alpha2-8 sialyltransferase) and SAT-4 (CMP-NeuAc: GM1a alpha2-3 sialyltransferase) was observed in the apoptotic carcinoma cells treated with L-PPMP compared with cis-platin.
T13 1663-1928 Sentence denotes A sharp decrease of activities of the glycolipid sialyltransferases: SAT-2 (CMP-NeuAc; GD3 alpha2-8 sialyltransferase) and SAT-4 (CMP-NeuAc: GM1a alpha2-3 sialyltransferase) was observed in the apoptotic carcinoma cells treated with L-PPMP compared with cis-platin.