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Annnotations TAB TSV DIC JSON TextAE Lectin_function IAV-Glycan

Id Subject Object Predicate Lexical cue
TextSentencer_T1 0-84 Sentence denotes Label-free protein quantification using LC-coupled ion trap or FT mass spectrometry:
T1 0-84 Sentence denotes Label-free protein quantification using LC-coupled ion trap or FT mass spectrometry:
TextSentencer_T2 85-152 Sentence denotes Reproducibility, linearity, and application with complex proteomes.
T2 85-152 Sentence denotes Reproducibility, linearity, and application with complex proteomes.
TextSentencer_T3 153-294 Sentence denotes A critical step in protein biomarker discovery is the ability to contrast proteomes, a process referred generally as quantitative proteomics.
T3 153-294 Sentence denotes A critical step in protein biomarker discovery is the ability to contrast proteomes, a process referred generally as quantitative proteomics.
TextSentencer_T4 295-594 Sentence denotes While stable-isotope labeling (e.g., ICAT, 18O- or 15N-labeling, or AQUA) remains the core technology used in mass spectrometry-based proteomic quantification, increasing efforts have been directed to the label-free approach that relies on direct comparison of peptide peak areas between LC-MS runs.
T4 295-594 Sentence denotes While stable-isotope labeling (e.g., ICAT, 18O- or 15N-labeling, or AQUA) remains the core technology used in mass spectrometry-based proteomic quantification, increasing efforts have been directed to the label-free approach that relies on direct comparison of peptide peak areas between LC-MS runs.
TextSentencer_T5 595-696 Sentence denotes This latter approach is attractive to investigators for its simplicity as well as cost effectiveness.
T5 595-696 Sentence denotes This latter approach is attractive to investigators for its simplicity as well as cost effectiveness.
TextSentencer_T6 697-827 Sentence denotes In the present study, the reproducibility and linearity of using a label-free approach to highly complex proteomes were evaluated.
T6 697-827 Sentence denotes In the present study, the reproducibility and linearity of using a label-free approach to highly complex proteomes were evaluated.
TextSentencer_T7 828-980 Sentence denotes Various amounts of proteins from different proteomes were subjected to repeated LC-MS analyses using an ion trap or Fourier transform mass spectrometer.
T7 828-980 Sentence denotes Various amounts of proteins from different proteomes were subjected to repeated LC-MS analyses using an ion trap or Fourier transform mass spectrometer.
TextSentencer_T8 981-1179 Sentence denotes Highly reproducible data were obtained between replicated runs, as evidenced by nearly ideal Pearson's correlation coefficients (for ion's peak areas or retention time) and average peak area ratios.
T8 981-1179 Sentence denotes Highly reproducible data were obtained between replicated runs, as evidenced by nearly ideal Pearson's correlation coefficients (for ion's peak areas or retention time) and average peak area ratios.
TextSentencer_T9 1180-1328 Sentence denotes In general, more than 50% and nearly 90% of the peptide ion ratios deviated less than 10% and 20%, respectively, from the average in duplicate runs.
T9 1180-1328 Sentence denotes In general, more than 50% and nearly 90% of the peptide ion ratios deviated less than 10% and 20%, respectively, from the average in duplicate runs.
TextSentencer_T10 1329-1498 Sentence denotes In addition, the multiplicity ratios of the amounts of proteins used correlated nicely with the observed averaged ratios of peak areas calculated from detected peptides.
T10 1329-1498 Sentence denotes In addition, the multiplicity ratios of the amounts of proteins used correlated nicely with the observed averaged ratios of peak areas calculated from detected peptides.
TextSentencer_T11 1499-1617 Sentence denotes Furthermore, the removal of abundant proteins from the samples led to an improvement in reproducibility and linearity.
T11 1499-1617 Sentence denotes Furthermore, the removal of abundant proteins from the samples led to an improvement in reproducibility and linearity.
TextSentencer_T12 1618-1768 Sentence denotes A computer program has been written to automate the processing of data sets from experiments with groups of multiple samples for statistical analysis.
T12 1618-1768 Sentence denotes A computer program has been written to automate the processing of data sets from experiments with groups of multiple samples for statistical analysis.
TextSentencer_T13 1769-1956 Sentence denotes Algorithms for outlier-resistant mean estimation and for adjusting statistical significance threshold in multiplicity of testing were incorporated to minimize the rate of false positives.
T13 1769-1956 Sentence denotes Algorithms for outlier-resistant mean estimation and for adjusting statistical significance threshold in multiplicity of testing were incorporated to minimize the rate of false positives.
TextSentencer_T14 1957-2104 Sentence denotes The program was applied to quantify changes in proteomes of parental and p53-deficient HCT-116 human cells and found to yield reproducible results.
T14 1957-2104 Sentence denotes The program was applied to quantify changes in proteomes of parental and p53-deficient HCT-116 human cells and found to yield reproducible results.
TextSentencer_T15 2105-2254 Sentence denotes Overall, this study demonstrates an alternative approach that allows global quantification of differentially expressed proteins in complex proteomes.
T15 2105-2254 Sentence denotes Overall, this study demonstrates an alternative approach that allows global quantification of differentially expressed proteins in complex proteomes.
TextSentencer_T16 2255-2404 Sentence denotes The utility of this method to biomarker discovery is likely to synergize with future improvements in the detecting sensitivity of mass spectrometers.
T16 2255-2404 Sentence denotes The utility of this method to biomarker discovery is likely to synergize with future improvements in the detecting sensitivity of mass spectrometers.